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The map label for this gene is fadB [H]

Identifier: 34498175

GI number: 34498175

Start: 2946579

End: 2948954

Strand: Reverse

Name: fadB [H]

Synonym: CV_2720

Alternate gene names: 34498175

Gene position: 2948954-2946579 (Counterclockwise)

Preceding gene: 34498176

Following gene: 34498174

Centisome position: 62.07

GC content: 64.98

Gene sequence:

>2376_bases
ATGTCTCAAACCAAATTCAATGTACGCAAGGTTGCCGTGCTCGGTGCCGGCGTGATGGGGGCGCAGATCGCCGCCCACCT
GGTGAACGCCAAGGTACCGACCATTCTGTTCGACCTGCCGGCCAAGGAAGGCGACAAGAACGGCATCGCGCTGAAGGCTA
TTGACGGTCTCAAGAAGCTGAAACCCTCTCCGCTGGCCGGCAGCGACGTGGTCGCCCACATCCAGCCCGCCAACTACGAC
GACCACCTGCACCTGCTGAAAGACTGCGACCTGGTGATCGAAGCCATCGCCGAGCGCATGGACTGGAAAGTGGACCTGTA
CCACAAGGTGGCGCCGCACCTGGGCGAGCACACCATCTTCGCCACCAACACCTCCGGCCTGTCGATCAACAAGCTGGCCG
AAGGCTGCCCGGACGCGGTGCGTCCGCGCTTCTGCGGCGTGCACTTCTTCAACCCGCCGCGCTACATGCACCTGGTTGAA
ATCATCCCTTGCGTGACCTCCGACGCCCATATCCTGGACAACCTGGAACGCTTCCTGGTGTCCACGCTGGGCAAGGGCGT
GGTGCGCGCCAAGGACACCCCGAACTTCGTCGCCAACCGCATCGGCGTATTCTCGATGCTGGCCACCATCGCCAACGCCG
CCAAATACGGCATCCGCTTCGACGTGGTGGACGACCTGACCGGCCCGCGCCTGGGTCGTCCGAAGTCCGCCACCTTCCGC
ACCGCCGACGTGGTGGGCCTGGATACCTTCGCCCACGTGGTGAAGACCATGCAGGACACGCTGCCGCAAGACCCGTGGCA
TAGCCTGTTCGCCACCCCGGACTGGATGCAGCAACTGATCGCCAATGGCGCGCTGGGCGCCAAGACCAAGGCCGGCATCT
ACAAGAAAGACGGCAAGCGCATGCTGGTGCTGGATCCTGCCAAGGGCGAATATGTCGGCTCCGGCGAGAAGGGCGACGAT
GCGGTCAAGGACATCCTGAAGATCGCCAATCCGGCGGAGAAATTCCAGAAGCTGCGCGAGAGCGAGCATCCGCAAGCGCA
GTTCCTGTGGGCATGTTTCCGCGACGTGTTCCACTACATCTCCTTCCATCTGGCCGACATCGCCAACTGCGCCCGCGATG
TGGACTTCGCCATCCGCTGGGGCTTCGGCTGGTCTGCCGGCCCGTTCGAGACCTGGCAGGCTGCCGGCTGGCAGCAGGTA
GCCAAGTGGCTGCAGGAAGACATCGCCGCGGGCAAGAGCCTGGCCAAGGCCGAGCTGCCAGCCTGGGTGCTGGAAGGCGA
CCGCGCCGGCGTGCATTTCGCCGACGGCTCCTACAACGCCGGCGACAAGAAGCTGGTAGGCCGTTCCGCGCTGGATGTGT
ACCAGCGCCAGCTGGCGCCGGCCAAGGTGCTGGGCGAGAAGATCGAACAACTGGGCGAAACCGTGTTCGAGAACGAGGGC
GTGCGCGCCTTCACCACCGGCGACGAGGTGCTGGTGGTGTCGTTCAAGTCCAAGGCCCACGCCATCGGCCCGGCCGTGCT
GGACGGCCTGAACACCGCGTTGGACATCGCCGAGGACCGTTTCAAGGGCCTGGTGATCTGGCAGACCGAGGAGCCGTTCT
CCGTCGGCGCCGACCTGCAGGCGATGATGCCGGCCTTCATGATGGGCGACTGGGGCGCGATCGAGGCGACGCTGAGCCGC
TTCCAGGCGACCGCGCTGCGCCTGCGCTACAGCCAGATCCCGACCATCGCCGCGACCCAGGGCTATGTGTTCGGCGGCGG
CTGCGAGTTCGCCATGCACTGCGACAAGACCGTGGCCGCGCTGGAATCCTACGTCGGCCTGGTGGAAGTCGGCGTCGGCC
TGCTGCCGGGCGGCGGCGGCTGCAAGGAGTTCGCGCTGCGCGCCTCGCAAGAGTCCAAGGGCGACTTGCTGGCCGCGTTG
AAGGACTACTTCATGAGCATCGCCACCGCCAAGGTCGCCACCAGCGGCGTGGAAGCGCAGGAGCTGGGCTTCTTCAAGAA
GGGCGACGCCGTGGTGTTCAACGCCTACGAGCTCTTGTATGTCGCCAAGCAGCAGGCGCTGGCGCTGGCCGAATCCGGCT
ACCGTCCGCCACTGAAGGTGAAGGGCTTCCCGGTGGCGGGCCGCTCCGGCGCCGCGTCCATCAAGGGCCAACTGGTGAAC
ATGCTGGAAGGCAACTTCATCAGCCAGCACGACTTCTTCATCGCCTCGCAGATCGCCGACGTGATGACCGGCGGCGACGT
GGAAGCCGGCACCCTGGTCAACGAGCAATGGATTCTGGACCTGGAGCGCAAGGCCTTCATGACCCTGCTGAAGAACTCCA
AGACCCAGGACCGCATCGCCAACATGCTGACCACCGGCAAGCCGCTGCGCAACTAA

Upstream 100 bases:

>100_bases
CGGGCAATGGGCAAGGACGATTTCAACGCCCGTCCTTGAAGCAAGCAGGACAGGTTGAGAGGGGCCTGTCTCATGTGTGT
TTCAACAAAACGAGGAAACC

Downstream 100 bases:

>100_bases
GTACTTGGGGATGATTCTGCTGCGCGCGCCGATCTCGAATGCTGCGATGCTCGCCGTACCGCATGTACGGTTGCGCTTCT
CGCTTCGACCTCGGCCCGCT

Product: 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 791; Mature: 790

Protein sequence:

>791_residues
MSQTKFNVRKVAVLGAGVMGAQIAAHLVNAKVPTILFDLPAKEGDKNGIALKAIDGLKKLKPSPLAGSDVVAHIQPANYD
DHLHLLKDCDLVIEAIAERMDWKVDLYHKVAPHLGEHTIFATNTSGLSINKLAEGCPDAVRPRFCGVHFFNPPRYMHLVE
IIPCVTSDAHILDNLERFLVSTLGKGVVRAKDTPNFVANRIGVFSMLATIANAAKYGIRFDVVDDLTGPRLGRPKSATFR
TADVVGLDTFAHVVKTMQDTLPQDPWHSLFATPDWMQQLIANGALGAKTKAGIYKKDGKRMLVLDPAKGEYVGSGEKGDD
AVKDILKIANPAEKFQKLRESEHPQAQFLWACFRDVFHYISFHLADIANCARDVDFAIRWGFGWSAGPFETWQAAGWQQV
AKWLQEDIAAGKSLAKAELPAWVLEGDRAGVHFADGSYNAGDKKLVGRSALDVYQRQLAPAKVLGEKIEQLGETVFENEG
VRAFTTGDEVLVVSFKSKAHAIGPAVLDGLNTALDIAEDRFKGLVIWQTEEPFSVGADLQAMMPAFMMGDWGAIEATLSR
FQATALRLRYSQIPTIAATQGYVFGGGCEFAMHCDKTVAALESYVGLVEVGVGLLPGGGGCKEFALRASQESKGDLLAAL
KDYFMSIATAKVATSGVEAQELGFFKKGDAVVFNAYELLYVAKQQALALAESGYRPPLKVKGFPVAGRSGAASIKGQLVN
MLEGNFISQHDFFIASQIADVMTGGDVEAGTLVNEQWILDLERKAFMTLLKNSKTQDRIANMLTTGKPLRN

Sequences:

>Translated_791_residues
MSQTKFNVRKVAVLGAGVMGAQIAAHLVNAKVPTILFDLPAKEGDKNGIALKAIDGLKKLKPSPLAGSDVVAHIQPANYD
DHLHLLKDCDLVIEAIAERMDWKVDLYHKVAPHLGEHTIFATNTSGLSINKLAEGCPDAVRPRFCGVHFFNPPRYMHLVE
IIPCVTSDAHILDNLERFLVSTLGKGVVRAKDTPNFVANRIGVFSMLATIANAAKYGIRFDVVDDLTGPRLGRPKSATFR
TADVVGLDTFAHVVKTMQDTLPQDPWHSLFATPDWMQQLIANGALGAKTKAGIYKKDGKRMLVLDPAKGEYVGSGEKGDD
AVKDILKIANPAEKFQKLRESEHPQAQFLWACFRDVFHYISFHLADIANCARDVDFAIRWGFGWSAGPFETWQAAGWQQV
AKWLQEDIAAGKSLAKAELPAWVLEGDRAGVHFADGSYNAGDKKLVGRSALDVYQRQLAPAKVLGEKIEQLGETVFENEG
VRAFTTGDEVLVVSFKSKAHAIGPAVLDGLNTALDIAEDRFKGLVIWQTEEPFSVGADLQAMMPAFMMGDWGAIEATLSR
FQATALRLRYSQIPTIAATQGYVFGGGCEFAMHCDKTVAALESYVGLVEVGVGLLPGGGGCKEFALRASQESKGDLLAAL
KDYFMSIATAKVATSGVEAQELGFFKKGDAVVFNAYELLYVAKQQALALAESGYRPPLKVKGFPVAGRSGAASIKGQLVN
MLEGNFISQHDFFIASQIADVMTGGDVEAGTLVNEQWILDLERKAFMTLLKNSKTQDRIANMLTTGKPLRN
>Mature_790_residues
SQTKFNVRKVAVLGAGVMGAQIAAHLVNAKVPTILFDLPAKEGDKNGIALKAIDGLKKLKPSPLAGSDVVAHIQPANYDD
HLHLLKDCDLVIEAIAERMDWKVDLYHKVAPHLGEHTIFATNTSGLSINKLAEGCPDAVRPRFCGVHFFNPPRYMHLVEI
IPCVTSDAHILDNLERFLVSTLGKGVVRAKDTPNFVANRIGVFSMLATIANAAKYGIRFDVVDDLTGPRLGRPKSATFRT
ADVVGLDTFAHVVKTMQDTLPQDPWHSLFATPDWMQQLIANGALGAKTKAGIYKKDGKRMLVLDPAKGEYVGSGEKGDDA
VKDILKIANPAEKFQKLRESEHPQAQFLWACFRDVFHYISFHLADIANCARDVDFAIRWGFGWSAGPFETWQAAGWQQVA
KWLQEDIAAGKSLAKAELPAWVLEGDRAGVHFADGSYNAGDKKLVGRSALDVYQRQLAPAKVLGEKIEQLGETVFENEGV
RAFTTGDEVLVVSFKSKAHAIGPAVLDGLNTALDIAEDRFKGLVIWQTEEPFSVGADLQAMMPAFMMGDWGAIEATLSRF
QATALRLRYSQIPTIAATQGYVFGGGCEFAMHCDKTVAALESYVGLVEVGVGLLPGGGGCKEFALRASQESKGDLLAALK
DYFMSIATAKVATSGVEAQELGFFKKGDAVVFNAYELLYVAKQQALALAESGYRPPLKVKGFPVAGRSGAASIKGQLVNM
LEGNFISQHDFFIASQIADVMTGGDVEAGTLVNEQWILDLERKAFMTLLKNSKTQDRIANMLTTGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=300, Percent_Identity=33, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI296179427, Length=317, Percent_Identity=31.8611987381703, Blast_Score=116, Evalue=1e-25,
Organism=Homo sapiens, GI20127408, Length=294, Percent_Identity=28.2312925170068, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1787661, Length=459, Percent_Identity=23.9651416122004, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1790281, Length=344, Percent_Identity=29.0697674418605, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788682, Length=356, Percent_Identity=25.8426966292135, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17553560, Length=301, Percent_Identity=31.2292358803987, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17563036, Length=295, Percent_Identity=30.8474576271186, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17558304, Length=390, Percent_Identity=27.6923076923077, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17549919, Length=303, Percent_Identity=30.6930693069307, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17508951, Length=408, Percent_Identity=28.6764705882353, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17508953, Length=409, Percent_Identity=28.8508557457213, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25144276, Length=300, Percent_Identity=32.6666666666667, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71985923, Length=303, Percent_Identity=27.0627062706271, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19921000, Length=302, Percent_Identity=29.4701986754967, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24583077, Length=302, Percent_Identity=29.4701986754967, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583079, Length=302, Percent_Identity=29.4701986754967, Blast_Score=89, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 85930; Mature: 85798

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTKFNVRKVAVLGAGVMGAQIAAHLVNAKVPTILFDLPAKEGDKNGIALKAIDGLKKL
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHC
KPSPLAGSDVVAHIQPANYDDHLHLLKDCDLVIEAIAERMDWKVDLYHKVAPHLGEHTIF
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEE
ATNTSGLSINKLAEGCPDAVRPRFCGVHFFNPPRYMHLVEIIPCVTSDAHILDNLERFLV
EECCCCCCHHHHHHCCCHHCCCCCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
STLGKGVVRAKDTPNFVANRIGVFSMLATIANAAKYGIRFDVVDDLTGPRLGRPKSATFR
HHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCEE
TADVVGLDTFAHVVKTMQDTLPQDPWHSLFATPDWMQQLIANGALGAKTKAGIYKKDGKR
EHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCEECCCCE
MLVLDPAKGEYVGSGEKGDDAVKDILKIANPAEKFQKLRESEHPQAQFLWACFRDVFHYI
EEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SFHLADIANCARDVDFAIRWGFGWSAGPFETWQAAGWQQVAKWLQEDIAAGKSLAKAELP
HHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCHHHHHHHCC
AWVLEGDRAGVHFADGSYNAGDKKLVGRSALDVYQRQLAPAKVLGEKIEQLGETVFENEG
EEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
VRAFTTGDEVLVVSFKSKAHAIGPAVLDGLNTALDIAEDRFKGLVIWQTEEPFSVGADLQ
CEEEECCCEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHH
AMMPAFMMGDWGAIEATLSRFQATALRLRYSQIPTIAATQGYVFGGGCEFAMHCDKTVAA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEECCCCEEHHHHHHHHH
LESYVGLVEVGVGLLPGGGGCKEFALRASQESKGDLLAALKDYFMSIATAKVATSGVEAQ
HHHHHHHHHHCCEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELGFFKKGDAVVFNAYELLYVAKQQALALAESGYRPPLKVKGFPVAGRSGAASIKGQLVN
HCCCEECCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHH
MLEGNFISQHDFFIASQIADVMTGGDVEAGTLVNEQWILDLERKAFMTLLKNSKTQDRIA
HHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCHHHEEHHHHHHHHHHHCCCHHHHHH
NMLTTGKPLRN
HHHHCCCCCCC
>Mature Secondary Structure 
SQTKFNVRKVAVLGAGVMGAQIAAHLVNAKVPTILFDLPAKEGDKNGIALKAIDGLKKL
CCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHC
KPSPLAGSDVVAHIQPANYDDHLHLLKDCDLVIEAIAERMDWKVDLYHKVAPHLGEHTIF
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEE
ATNTSGLSINKLAEGCPDAVRPRFCGVHFFNPPRYMHLVEIIPCVTSDAHILDNLERFLV
EECCCCCCHHHHHHCCCHHCCCCCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
STLGKGVVRAKDTPNFVANRIGVFSMLATIANAAKYGIRFDVVDDLTGPRLGRPKSATFR
HHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCEE
TADVVGLDTFAHVVKTMQDTLPQDPWHSLFATPDWMQQLIANGALGAKTKAGIYKKDGKR
EHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCEECCCCE
MLVLDPAKGEYVGSGEKGDDAVKDILKIANPAEKFQKLRESEHPQAQFLWACFRDVFHYI
EEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SFHLADIANCARDVDFAIRWGFGWSAGPFETWQAAGWQQVAKWLQEDIAAGKSLAKAELP
HHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCHHHHHHHCC
AWVLEGDRAGVHFADGSYNAGDKKLVGRSALDVYQRQLAPAKVLGEKIEQLGETVFENEG
EEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
VRAFTTGDEVLVVSFKSKAHAIGPAVLDGLNTALDIAEDRFKGLVIWQTEEPFSVGADLQ
CEEEECCCEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHH
AMMPAFMMGDWGAIEATLSRFQATALRLRYSQIPTIAATQGYVFGGGCEFAMHCDKTVAA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEECCCCEEHHHHHHHHH
LESYVGLVEVGVGLLPGGGGCKEFALRASQESKGDLLAALKDYFMSIATAKVATSGVEAQ
HHHHHHHHHHCCEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELGFFKKGDAVVFNAYELLYVAKQQALALAESGYRPPLKVKGFPVAGRSGAASIKGQLVN
HCCCEECCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHH
MLEGNFISQHDFFIASQIADVMTGGDVEAGTLVNEQWILDLERKAFMTLLKNSKTQDRIA
HHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCHHHEEHHHHHHHHHHHCCCHHHHHH
NMLTTGKPLRN
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]