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The map label for this gene is lipH

Identifier: 34498168

GI number: 34498168

Start: 2936687

End: 2937598

Strand: Reverse

Name: lipH

Synonym: CV_2713

Alternate gene names: 34498168

Gene position: 2937598-2936687 (Counterclockwise)

Preceding gene: 34498169

Following gene: 34498166

Centisome position: 61.83

GC content: 70.5

Gene sequence:

>912_bases
ATGCGCGGCCTCGGCTTGACGCTGGCGGCGGCTTGCGCCGCCTGGCTGGCCTGGTGGGCCTGGCCGGACGGCGCCCACTC
CGAAGCCGCCGCTGCCCGGCAGGCCGCGCGCGGCGGTTTCGCCCCGTCGCTGATCGGCACCCGTCCGGACGGCGCCGCCG
CCGAAGCGGACGGCAAGCTGGTGGTCGACCAGCAGTTGCGCCAGCTGTTTGACTATTATCTGGCCACGCTGGGGGAGCGC
GACCTGGCCGTCATCCGGACGGAGCTGCAGGGGCAATTGAAGCGGTCGCTGAAAAATGGGCCGTTGGCTCAAGCCATGGG
TCTGTTCGACCGTTACGTCGGCTACAAGCGCTCGCTGGCCGGCAAGGCGGCCGCCGCCGCCACGGATCTGTCGCATCGGC
TGGAGCTGGTGCAGGCCGCTAGGCGGCAGTATTTCAGCCAGGCGGAACTGGACGGCTTGTTCGGCGACGAGGACCGCTAT
GACAACTTCACCGCCAGGCGGCTGGCGATCGAGGCCAATCCGGCCTTGAGCGTCGATGAAAAGCGGCGCAGGGTCGCGCA
ACTGGAGCAACAGCTGCCGCCCGGCTTGCGCGCCGCGCGCGAAGAGCCGGTCAAGCACCTGGCGCTGGCCGATGCCGAGG
CGCGGTTGCGGCAGGGCGGGGGCGGAGAGCAGCAACTGTACCAGCTGCGGGCCGGCATGGTCGGCCAGGCGGCGGCGGAC
AGGCTGGGCGAGCTGGATCGGGAGCAAGCCGCCTGGCAGAACAGGGTGGACGACTTCAAGCGGGAGCGGACGGCCATCCT
CGCCGATGGCGGGCTGAGCGCCCAGCAGCGGCAGCAGGCGCTCGCCCGGCTGCAGGCGCAGCGGTTTTCTCAACAGGAGT
CGCTGCGGCTGCCGGCTTATCTGTCCAACTGA

Upstream 100 bases:

>100_bases
GAGATCAACCAGAGCTTCGGCCTGGTCAGCCTGTTCGAGGTCAGTCCGGTTTCTCTGTATCGCCAGCAGGCCAACCGGCT
GAAGAACGCGGGGCTGTAAG

Downstream 100 bases:

>100_bases
GCCATGCCGAAATGAAACAGGCGCCATTGCGGCGCCTGTTTTTCATGGGGCGGCTTCGCGTCAGGATTGGGCGAAGAACA
GGCGGCTCAGCGCCTCGCCC

Product: lipase chaperone

Products: NA

Alternate protein names: Lipase activator protein; Lipase foldase; Lipase helper protein; Lipase modulator

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MRGLGLTLAAACAAWLAWWAWPDGAHSEAAAARQAARGGFAPSLIGTRPDGAAAEADGKLVVDQQLRQLFDYYLATLGER
DLAVIRTELQGQLKRSLKNGPLAQAMGLFDRYVGYKRSLAGKAAAAATDLSHRLELVQAARRQYFSQAELDGLFGDEDRY
DNFTARRLAIEANPALSVDEKRRRVAQLEQQLPPGLRAAREEPVKHLALADAEARLRQGGGGEQQLYQLRAGMVGQAAAD
RLGELDREQAAWQNRVDDFKRERTAILADGGLSAQQRQQALARLQAQRFSQQESLRLPAYLSN

Sequences:

>Translated_303_residues
MRGLGLTLAAACAAWLAWWAWPDGAHSEAAAARQAARGGFAPSLIGTRPDGAAAEADGKLVVDQQLRQLFDYYLATLGER
DLAVIRTELQGQLKRSLKNGPLAQAMGLFDRYVGYKRSLAGKAAAAATDLSHRLELVQAARRQYFSQAELDGLFGDEDRY
DNFTARRLAIEANPALSVDEKRRRVAQLEQQLPPGLRAAREEPVKHLALADAEARLRQGGGGEQQLYQLRAGMVGQAAAD
RLGELDREQAAWQNRVDDFKRERTAILADGGLSAQQRQQALARLQAQRFSQQESLRLPAYLSN
>Mature_303_residues
MRGLGLTLAAACAAWLAWWAWPDGAHSEAAAARQAARGGFAPSLIGTRPDGAAAEADGKLVVDQQLRQLFDYYLATLGER
DLAVIRTELQGQLKRSLKNGPLAQAMGLFDRYVGYKRSLAGKAAAAATDLSHRLELVQAARRQYFSQAELDGLFGDEDRY
DNFTARRLAIEANPALSVDEKRRRVAQLEQQLPPGLRAAREEPVKHLALADAEARLRQGGGGEQQLYQLRAGMVGQAAAD
RLGELDREQAAWQNRVDDFKRERTAILADGGLSAQQRQQALARLQAQRFSQQESLRLPAYLSN

Specific function: May be involved in the folding of the extracellular lipase during its passage through the periplasm

COG id: COG5380

COG function: function code O; Lipase chaperone

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase chaperone family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LIFO_CHRVO (Q7NUI5)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_902383.1
- ProteinModelPortal:   Q7NUI5
- SMR:   Q7NUI5
- GeneID:   2549877
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2713
- NMPDR:   fig|243365.1.peg.2713
- OMA:   LITRDIR
- ProtClustDB:   PRK01294
- BioCyc:   CVIO243365:CV_2713-MONOMER
- HAMAP:   MF_00790
- InterPro:   IPR004961

Pfam domain/function: PF03280 Lipase_chap

EC number: NA

Molecular weight: Translated: 33276; Mature: 33276

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xef77f88)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLGLTLAAACAAWLAWWAWPDGAHSEAAAARQAARGGFAPSLIGTRPDGAAAEADGKL
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE
VVDQQLRQLFDYYLATLGERDLAVIRTELQGQLKRSLKNGPLAQAMGLFDRYVGYKRSLA
EHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GKAAAAATDLSHRLELVQAARRQYFSQAELDGLFGDEDRYDNFTARRLAIEANPALSVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEEEECCCCCCHHH
KRRRVAQLEQQLPPGLRAAREEPVKHLALADAEARLRQGGGGEQQLYQLRAGMVGQAAAD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RLGELDREQAAWQNRVDDFKRERTAILADGGLSAQQRQQALARLQAQRFSQQESLRLPAY
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
LSN
CCH
>Mature Secondary Structure
MRGLGLTLAAACAAWLAWWAWPDGAHSEAAAARQAARGGFAPSLIGTRPDGAAAEADGKL
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE
VVDQQLRQLFDYYLATLGERDLAVIRTELQGQLKRSLKNGPLAQAMGLFDRYVGYKRSLA
EHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GKAAAAATDLSHRLELVQAARRQYFSQAELDGLFGDEDRYDNFTARRLAIEANPALSVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEEEECCCCCCHHH
KRRRVAQLEQQLPPGLRAAREEPVKHLALADAEARLRQGGGGEQQLYQLRAGMVGQAAAD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RLGELDREQAAWQNRVDDFKRERTAILADGGLSAQQRQQALARLQAQRFSQQESLRLPAY
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
LSN
CCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782