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The map label for this gene is appC [H]

Identifier: 34498141

GI number: 34498141

Start: 2907947

End: 2909002

Strand: Reverse

Name: appC [H]

Synonym: CV_2686

Alternate gene names: 34498141

Gene position: 2909002-2907947 (Counterclockwise)

Preceding gene: 34498142

Following gene: 34498140

Centisome position: 61.23

GC content: 64.11

Gene sequence:

>1056_bases
ATGACGACATTGCAGAATACCGCCGGCGCCGCGCCGGCCGCCGTCCCGTCCCGCAGCCTGTGGGCGCTGGGCTGGCAACG
CTTGAAGCGCGACCGCATCGGTTTCGCGTGCTTGTGGATTGTAACCGGCTTCATGCTGCTGGCCTTGTGCAGCTGGGTCG
GCCTGATCGGCCGCGGTTGGAATGCCGAGGTGGCAGTGTCCTACGCGCCGCCTACTTTCCTGTATCAGCAGGCGCATGAT
GCTGCCCAGACCTCTGGCGCGAAAAAAGCCGAGACGGTCACGGGAACCGGCCTGCGTCCTGAGGAAGACCCGATCTGGGC
GGAAACCCAGGCGGCGATGAAGAACCGCGACAAGTACGTGGTGCCGGAAGTGAAGAAGGCGGAGTCGCTGACGTTCGGCG
CGGACATCCGCGGCCGCGACATCCTGGACAAGGTGGTCAAGGGCACGTCCACTTCATTGTTCGTCGGCTTCTTCGGCGCC
TTGCTGTCGGTGGTGATCGGCGCGTCGCTGGGCGCTTGCGCCGGTTTCCTCGGCCGCAAGATCGATGATTTCCTGATGTG
GTTCTACAACGTATTCACCGCCATGCCGGACATGCTGCTGTTGCTGGCTTTCGCCGCGGTGGCCGGCCGCGGCCTGGGCA
CGGTGATCCTGGTGCTGTCGCTGACCAGCTGGCCCGGCACTTTCCGCCTGGTGCGCGCCGAATTCATCAAGCTGCGCTCG
CGCGAATTCGTGCAGGCGGCGGACGCCATCGGCGCCAGCAGCGCGCGCCGGATGTTCGTTCACATCCTGCCGAATGTCTC
CCACCTGCTCTTGGTGCAGTTTTCCTTGCTGATGGTGGGCCTGATCAAGTACGAGGTGATCCTGTCCTTCCTGGGCTTCG
GCGTGGATGTGCGCCAGGTCAGCTGGGGCTCGATGCTGTCCGAGGTGCCGGAAGAGCTGATGCAGGGCTACTGGTGGCAG
TTGGCGATGGTGGTGGTGTTCATGTCGCTGCTGGTCACGGCCTTCAGCATGCTGACCGATTCCCTGCGCGACGCGCTGGA
CCCCAAGGTAAAGTGA

Upstream 100 bases:

>100_bases
ATCACTATCGCCGCCGCGGCCATGGTGTTCAACCTGCTGGCGGATGTCCTGTACAAGTGGATCGATCCGCGCGTCCAGCT
GAAGTAAGGGGAGAGAGACG

Downstream 100 bases:

>100_bases
GGATCACACCATGAGCAATAACAAAACCCTGCTTTCGGTGCGCAACCTGCGGGTGCGTTTCCGCCAGGAGGACGGCGGCC
GCTTCGAGGCGCTGAAGGGC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTTLQNTAGAAPAAVPSRSLWALGWQRLKRDRIGFACLWIVTGFMLLALCSWVGLIGRGWNAEVAVSYAPPTFLYQQAHD
AAQTSGAKKAETVTGTGLRPEEDPIWAETQAAMKNRDKYVVPEVKKAESLTFGADIRGRDILDKVVKGTSTSLFVGFFGA
LLSVVIGASLGACAGFLGRKIDDFLMWFYNVFTAMPDMLLLLAFAAVAGRGLGTVILVLSLTSWPGTFRLVRAEFIKLRS
REFVQAADAIGASSARRMFVHILPNVSHLLLVQFSLLMVGLIKYEVILSFLGFGVDVRQVSWGSMLSEVPEELMQGYWWQ
LAMVVVFMSLLVTAFSMLTDSLRDALDPKVK

Sequences:

>Translated_351_residues
MTTLQNTAGAAPAAVPSRSLWALGWQRLKRDRIGFACLWIVTGFMLLALCSWVGLIGRGWNAEVAVSYAPPTFLYQQAHD
AAQTSGAKKAETVTGTGLRPEEDPIWAETQAAMKNRDKYVVPEVKKAESLTFGADIRGRDILDKVVKGTSTSLFVGFFGA
LLSVVIGASLGACAGFLGRKIDDFLMWFYNVFTAMPDMLLLLAFAAVAGRGLGTVILVLSLTSWPGTFRLVRAEFIKLRS
REFVQAADAIGASSARRMFVHILPNVSHLLLVQFSLLMVGLIKYEVILSFLGFGVDVRQVSWGSMLSEVPEELMQGYWWQ
LAMVVVFMSLLVTAFSMLTDSLRDALDPKVK
>Mature_350_residues
TTLQNTAGAAPAAVPSRSLWALGWQRLKRDRIGFACLWIVTGFMLLALCSWVGLIGRGWNAEVAVSYAPPTFLYQQAHDA
AQTSGAKKAETVTGTGLRPEEDPIWAETQAAMKNRDKYVVPEVKKAESLTFGADIRGRDILDKVVKGTSTSLFVGFFGAL
LSVVIGASLGACAGFLGRKIDDFLMWFYNVFTAMPDMLLLLAFAAVAGRGLGTVILVLSLTSWPGTFRLVRAEFIKLRSR
EFVQAADAIGASSARRMFVHILPNVSHLLLVQFSLLMVGLIKYEVILSFLGFGVDVRQVSWGSMLSEVPEELMQGYWWQL
AMVVVFMSLLVTAFSMLTDSLRDALDPKVK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=221, Percent_Identity=35.7466063348416, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789964, Length=248, Percent_Identity=35.0806451612903, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787760, Length=218, Percent_Identity=31.1926605504587, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787498, Length=242, Percent_Identity=33.4710743801653, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788505, Length=335, Percent_Identity=25.3731343283582, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789889, Length=223, Percent_Identity=32.2869955156951, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787549, Length=224, Percent_Identity=25, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38473; Mature: 38341

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLQNTAGAAPAAVPSRSLWALGWQRLKRDRIGFACLWIVTGFMLLALCSWVGLIGRGW
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NAEVAVSYAPPTFLYQQAHDAAQTSGAKKAETVTGTGLRPEEDPIWAETQAAMKNRDKYV
CCCEEEEECCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEE
VPEVKKAESLTFGADIRGRDILDKVVKGTSTSLFVGFFGALLSVVIGASLGACAGFLGRK
CCCHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IDDFLMWFYNVFTAMPDMLLLLAFAAVAGRGLGTVILVLSLTSWPGTFRLVRAEFIKLRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
REFVQAADAIGASSARRMFVHILPNVSHLLLVQFSLLMVGLIKYEVILSFLGFGVDVRQV
HHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
SWGSMLSEVPEELMQGYWWQLAMVVVFMSLLVTAFSMLTDSLRDALDPKVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTLQNTAGAAPAAVPSRSLWALGWQRLKRDRIGFACLWIVTGFMLLALCSWVGLIGRGW
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NAEVAVSYAPPTFLYQQAHDAAQTSGAKKAETVTGTGLRPEEDPIWAETQAAMKNRDKYV
CCCEEEEECCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEE
VPEVKKAESLTFGADIRGRDILDKVVKGTSTSLFVGFFGALLSVVIGASLGACAGFLGRK
CCCHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IDDFLMWFYNVFTAMPDMLLLLAFAAVAGRGLGTVILVLSLTSWPGTFRLVRAEFIKLRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
REFVQAADAIGASSARRMFVHILPNVSHLLLVQFSLLMVGLIKYEVILSFLGFGVDVRQV
HHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
SWGSMLSEVPEELMQGYWWQLAMVVVFMSLLVTAFSMLTDSLRDALDPKVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]