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The map label for this gene is spaP [H]

Identifier: 34498079

GI number: 34498079

Start: 2831526

End: 2832188

Strand: Reverse

Name: spaP [H]

Synonym: CV_2624

Alternate gene names: 34498079

Gene position: 2832188-2831526 (Counterclockwise)

Preceding gene: 34498080

Following gene: 34498078

Centisome position: 59.61

GC content: 61.54

Gene sequence:

>663_bases
ATGTCGAATGATATCTCGCTGATCGCGCTGCTGGCGTTTTCCACGCTGCTGCCTTTCCTGATCGCGTCCGGAACCTGTTT
CGTCAAGTTCTCCATCGTGTTCGTCATGGTGCGCAACGCGCTGGGTCTGCAGCAAGTGCCGTCCAACATGACGCTCAACG
GCATCGCGCTGATGCTGTCGATGTTCGTGATGCTGCCGGTTGCGCAGCAGGCCTACGGCTACTACCAGGAAGAGCGCGTC
AGCTTCACCAGCGTGGAGGCGGTCAACAACTTCGTCGAAAACGGGCTGGATGGTTACCGCGGCTATCTGCAGAAGTATTC
CGACCCTGAGCTGACCCGCTTCTTCGAGAAGGCGCAGAGCCAGCGCAGCGAGCGCGACGGCGGCGAGGCGGCGGCGCCGG
ACGACAAGCCGTCCATCTTCGCGCTGCTGCCGGCCTACGCCCTCAGCGAGATCAAGAGCGCCTTCAAGATCGGCTTCTAC
CTCTACCTGCCCTTCGTGGTGGTGGACCTGGTGATCTCCAGCGTGCTGCTGGCGCTGGGCATGATGATGATGAGTCCGGT
GACGATATCGGTGCCGATCAAGCTGGTGCTGTTCGTGGCGCTGGACGGCTGGACGCTGCTGTCCAAGGGGCTGGTGCTGC
AGTACCTGGATTTGGCGACGTAG

Upstream 100 bases:

>100_bases
GAGCTGCGCGCCAACGGCGCGCTGCTGGGCCGAGGCGAGCTGGTGCAGCTGGACGGGCGGCTGGGCGTGGAAGTGGCGCA
ATGGCTGGGCGGGTCGGGCG

Downstream 100 bases:

>100_bases
AGGGAGTCCGCTGCGCGGACGGGGATTCGGGGCGCGTCGGATACGTGTTTGGTTTCATGCCCACGTGTTCAAGGCTTTTG
CTGATTGAGAGGTTTGTATG

Product: surface presentation of antigens protein SpaP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSNDISLIALLAFSTLLPFLIASGTCFVKFSIVFVMVRNALGLQQVPSNMTLNGIALMLSMFVMLPVAQQAYGYYQEERV
SFTSVEAVNNFVENGLDGYRGYLQKYSDPELTRFFEKAQSQRSERDGGEAAAPDDKPSIFALLPAYALSEIKSAFKIGFY
LYLPFVVVDLVISSVLLALGMMMMSPVTISVPIKLVLFVALDGWTLLSKGLVLQYLDLAT

Sequences:

>Translated_220_residues
MSNDISLIALLAFSTLLPFLIASGTCFVKFSIVFVMVRNALGLQQVPSNMTLNGIALMLSMFVMLPVAQQAYGYYQEERV
SFTSVEAVNNFVENGLDGYRGYLQKYSDPELTRFFEKAQSQRSERDGGEAAAPDDKPSIFALLPAYALSEIKSAFKIGFY
LYLPFVVVDLVISSVLLALGMMMMSPVTISVPIKLVLFVALDGWTLLSKGLVLQYLDLAT
>Mature_219_residues
SNDISLIALLAFSTLLPFLIASGTCFVKFSIVFVMVRNALGLQQVPSNMTLNGIALMLSMFVMLPVAQQAYGYYQEERVS
FTSVEAVNNFVENGLDGYRGYLQKYSDPELTRFFEKAQSQRSERDGGEAAAPDDKPSIFALLPAYALSEIKSAFKIGFYL
YLPFVVVDLVISSVLLALGMMMMSPVTISVPIKLVLFVALDGWTLLSKGLVLQYLDLAT

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: COG4790

COG function: function code U; Type III secretory pathway, component EscR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliP/mopC/spaP family [H]

Homologues:

Organism=Escherichia coli, GI1788259, Length=202, Percent_Identity=40.0990099009901, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005838
- InterPro:   IPR005773 [H]

Pfam domain/function: PF00813 FliP [H]

EC number: NA

Molecular weight: Translated: 24246; Mature: 24115

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS01060 FLIP_1 ; PS01061 FLIP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDISLIALLAFSTLLPFLIASGTCFVKFSIVFVMVRNALGLQQVPSNMTLNGIALMLS
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHH
MFVMLPVAQQAYGYYQEERVSFTSVEAVNNFVENGLDGYRGYLQKYSDPELTRFFEKAQS
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHH
QRSERDGGEAAAPDDKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVISSVLLALG
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMMMSPVTISVPIKLVLFVALDGWTLLSKGLVLQYLDLAT
HHHHCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNDISLIALLAFSTLLPFLIASGTCFVKFSIVFVMVRNALGLQQVPSNMTLNGIALMLS
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHH
MFVMLPVAQQAYGYYQEERVSFTSVEAVNNFVENGLDGYRGYLQKYSDPELTRFFEKAQS
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHH
QRSERDGGEAAAPDDKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVISSVLLALG
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMMMSPVTISVPIKLVLFVALDGWTLLSKGLVLQYLDLAT
HHHHCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7638176; 11677608; 12644504 [H]