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The map label for this gene is spaR [H]

Identifier: 34498077

GI number: 34498077

Start: 2830397

End: 2831164

Strand: Reverse

Name: spaR [H]

Synonym: CV_2622

Alternate gene names: 34498077

Gene position: 2831164-2830397 (Counterclockwise)

Preceding gene: 34498078

Following gene: 34498076

Centisome position: 59.59

GC content: 68.36

Gene sequence:

>768_bases
GTGCAGTTCAGCTTTTTCTTCGAGGTGCACGGCTGGGTGGCCGCGGCCGCCATCGGCTTCGCCCGCGTGGCGCCGGTGTT
CTTCATCCTGCCCTTCCTCAACGGCAACACGCTGACCGGCATGGTGCGCACCTCGGTGGCGATGCTGGTGGCGCTGGGCC
TGTGGCCGCACCCGCCGCTGGCCATGCACGCGATGCAGGCCTGGCCGTTGCTGGCGCTGCTGATGCGGGAGGCGACGGTC
GGCCTGTTGCTGGGCTGCCTGCTGGCCTGGCCGTTCTGGGCGTTCCACGCGATGGGCAGCATTATAGACAACCAGCGCGG
CGCCACGCTCAGCAGCAGCATCGATCCGGCCAACGGGGTGGATACCTCGGAAATGGCCAATCTGCTCAACCTGTTCGCCG
CCGCTGTCTACCTGCAGGGCGGCGGCATGGAGCTGATGCTGGACGTGATGCGCCAGAGCTATCAGCTGCTGGATCCGCTG
GGCGACGGCCTGCCGCCGCTGGCGCCGGTGCTGTCCCTGCTCAACCAGGTGATCGCCAAATCCATCGTGCTGGCCAGCCC
GGTGATGGCGACGCTGTTGTTGTCCGAGGCGGTGCTGGGCCTGTTGTCGCGCTTTGCGCCGCAGATGAACGCGTTCGCGG
TGTCGCTGACGGTGAAAAGCGCGGCGGCGCTGCTGATCATGCTGCTCTATTTCGCGCCGGTGCTGCCCGACGCGGTGGCC
GGCCTGGCCCTGCGCCCCGGCGCGCTGGGCACCTGGTTGGTGCGCTGA

Upstream 100 bases:

>100_bases
CGTCAGCGTGTGCCTGTTCCTGCTGTCCGGCTGGTACGGCGAGACCTTGCTCGCCTTCGGCCGCGAAGTGATGCGGCTGG
CGCTGGCCAAGGGATAGCGC

Downstream 100 bases:

>100_bases
CATGTCGTCCAACAAGACCGAGAAACCCACGCGCAAGAAGCTGCAGGACGCGGCCAAAAAGGGCCAGTCCTTCAAGAGCC
GCGACCTGGTGGTGGCCTGC

Product: surface presentation of antigens secretory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MQFSFFFEVHGWVAAAAIGFARVAPVFFILPFLNGNTLTGMVRTSVAMLVALGLWPHPPLAMHAMQAWPLLALLMREATV
GLLLGCLLAWPFWAFHAMGSIIDNQRGATLSSSIDPANGVDTSEMANLLNLFAAAVYLQGGGMELMLDVMRQSYQLLDPL
GDGLPPLAPVLSLLNQVIAKSIVLASPVMATLLLSEAVLGLLSRFAPQMNAFAVSLTVKSAAALLIMLLYFAPVLPDAVA
GLALRPGALGTWLVR

Sequences:

>Translated_255_residues
MQFSFFFEVHGWVAAAAIGFARVAPVFFILPFLNGNTLTGMVRTSVAMLVALGLWPHPPLAMHAMQAWPLLALLMREATV
GLLLGCLLAWPFWAFHAMGSIIDNQRGATLSSSIDPANGVDTSEMANLLNLFAAAVYLQGGGMELMLDVMRQSYQLLDPL
GDGLPPLAPVLSLLNQVIAKSIVLASPVMATLLLSEAVLGLLSRFAPQMNAFAVSLTVKSAAALLIMLLYFAPVLPDAVA
GLALRPGALGTWLVR
>Mature_255_residues
MQFSFFFEVHGWVAAAAIGFARVAPVFFILPFLNGNTLTGMVRTSVAMLVALGLWPHPPLAMHAMQAWPLLALLMREATV
GLLLGCLLAWPFWAFHAMGSIIDNQRGATLSSSIDPANGVDTSEMANLLNLFAAAVYLQGGGMELMLDVMRQSYQLLDPL
GDGLPPLAPVLSLLNQVIAKSIVLASPVMATLLLSEAVLGLLSRFAPQMNAFAVSLTVKSAAALLIMLLYFAPVLPDAVA
GLALRPGALGTWLVR

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: COG4791

COG function: function code U; Type III secretory pathway, component EscT

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002010
- InterPro:   IPR006304 [H]

Pfam domain/function: PF01311 Bac_export_1 [H]

EC number: NA

Molecular weight: Translated: 27140; Mature: 27140

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSFFFEVHGWVAAAAIGFARVAPVFFILPFLNGNTLTGMVRTSVAMLVALGLWPHPPL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHH
AMHAMQAWPLLALLMREATVGLLLGCLLAWPFWAFHAMGSIIDNQRGATLSSSIDPANGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DTSEMANLLNLFAAAVYLQGGGMELMLDVMRQSYQLLDPLGDGLPPLAPVLSLLNQVIAK
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SIVLASPVMATLLLSEAVLGLLSRFAPQMNAFAVSLTVKSAAALLIMLLYFAPVLPDAVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GLALRPGALGTWLVR
HHHCCCCCCHHHCCC
>Mature Secondary Structure
MQFSFFFEVHGWVAAAAIGFARVAPVFFILPFLNGNTLTGMVRTSVAMLVALGLWPHPPL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHH
AMHAMQAWPLLALLMREATVGLLLGCLLAWPFWAFHAMGSIIDNQRGATLSSSIDPANGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DTSEMANLLNLFAAAVYLQGGGMELMLDVMRQSYQLLDPLGDGLPPLAPVLSLLNQVIAK
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SIVLASPVMATLLLSEAVLGLLSRFAPQMNAFAVSLTVKSAAALLIMLLYFAPVLPDAVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GLALRPGALGTWLVR
HHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8404849; 11677609 [H]