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The map label for this gene is escC [H]

Identifier: 34498052

GI number: 34498052

Start: 2804918

End: 2806405

Strand: Reverse

Name: escC [H]

Synonym: CV_2597

Alternate gene names: 34498052

Gene position: 2806405-2804918 (Counterclockwise)

Preceding gene: 34498053

Following gene: 34498051

Centisome position: 59.07

GC content: 58.8

Gene sequence:

>1488_bases
ATGAGAGCATCGAAATGGCTTGGCCCTGGCTTGGTCGCATTGACTTGCGCACAGGCGTTCGCAGCTATCCCATGGCAGAG
TAGCGCGCCATTTTTCCTGTCCACTCGCGGCAGCAAGCTGGCGGATGTGCTGCGCGATCTGGGCGCCAATTACAGCGTCC
CGGTGGTGGTAAGCAAGCAGGTCGACGAGCCCTTTATCGGCGCGATCCGCAGCATGCCGCCGGAGCAGGCGCTGGATCAG
CTGGCGCGCCTGCATAAGCTGGCATGGTATTACGACGGGCAAGCCATCTACGTTTACAAAGCGCAAGAAGTGAGCAGCCA
GCTGATCACCCCCGCCTATCTGCAGGTGAGCACTTTGATCAGCCAATTGCAGGGCAGCGGCATTCTGGACCGGCGCTATT
GCCGGGTGCGCGCGGTGCCGGCGTCCAACGCGATGGAGGTGCATGGCGTGCCGATTTGCCTCAACCGGGTGGAACAGCTG
GCCAAGCGCATTGATGAGCAGAAGCTCAATCACGAACAAAACCAGGAAATCATCCAGCTGTTCCCGTTGAAATACGCTAC
CGCGGCGGATGGCAGCTACAGCTATCGCGGCCAACAGGTGGCGGTGCCGGGGGTGGTGAGCGTGCTGAAGGACATGGCGC
AGGGCCGCACGCTGCCATTGAAGGAAAACCAAGGCCAGCAGCCGCCGACCGACCGCAGCTTGCCGATGTTCTCGGCGGAT
CCGCGCCAGAACGCGGTCATTGTGCGTGATCGCAAAATCAATATGCCGCTATATGCCAGTTTGATTGAGCAGTTTGACCG
CAAACCGGCGTTGATTGAGGTGTCGGTGATGATCATCGATGTCAATTCCCAAGATTTGAGCGCATTGGGCATCGATTGGT
CGGCATCGGCCAGCATCGGCGGCAACGGCATCAGTTTCAACAGTGCTGGTCAGCAAGGCTCGGACAATTTCTCCACCGTG
ATTTCCAACACCGGTGGCTTCATGGTCAAGCTCAATGCGCTGCAACAGAAGGCCAAGGCGCAGATCCTGTCCCGTCCTTC
TGTTGTGACGCTGGATAACACCCAGGCGGTGCTGGACCGCAACATCACGTTCTACACCAAGCTGTTGGCGGAAAAAGTCG
CCAAATTGGAATCCATCTCCACCGGCTCTCTGCTACGGGTCACACCGCGGCTGGTTGATGAAGGCGGCCAGCGCAACGTG
ATGTTGACGCTGGTGATTCAGGATGGCCGCCAGGCCGGCACGGTCAGCCAGCATGAGCCGCTGCCGCAGACGCTGAATGC
TGAAGTGTCCACCCAGACACTGCTGAAAGCCGGTCAAAGCTTGTTGTTGGGCGGGTTTGTCCAGGACGAGCATAGCGAGG
GCGAGAGCAAGATTCCGTTGCTGGGCGATATCCCGCTGATAGGCAAATTGTTCCGCTCTACCCAGAAAAATAGCCGCAGC
ACCGTTCGCCTATTCCTGATCAAGGCCGAACCCGCGGTTCAGTCCTAA

Upstream 100 bases:

>100_bases
AGTGGGAAGCCACATTGAATCAGCAACTGGCCGTGGTGGCCTGGCTGGTCAAGCATGCTTCTTCGGTTTCATCCATTGGC
TCGGCAGCTGGGAGGCGGGT

Downstream 100 bases:

>100_bases
GGCGCAGTGAAAATGGAATATTTGTTCAAGCTGAAGTGGCTGAACGGCCCGCTGGCGGGGCGGGAGTTGGAATTGCCTGC
CGGTGAGCTCCGCTTGGGCG

Product: type III secretion system EscC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MRASKWLGPGLVALTCAQAFAAIPWQSSAPFFLSTRGSKLADVLRDLGANYSVPVVVSKQVDEPFIGAIRSMPPEQALDQ
LARLHKLAWYYDGQAIYVYKAQEVSSQLITPAYLQVSTLISQLQGSGILDRRYCRVRAVPASNAMEVHGVPICLNRVEQL
AKRIDEQKLNHEQNQEIIQLFPLKYATAADGSYSYRGQQVAVPGVVSVLKDMAQGRTLPLKENQGQQPPTDRSLPMFSAD
PRQNAVIVRDRKINMPLYASLIEQFDRKPALIEVSVMIIDVNSQDLSALGIDWSASASIGGNGISFNSAGQQGSDNFSTV
ISNTGGFMVKLNALQQKAKAQILSRPSVVTLDNTQAVLDRNITFYTKLLAEKVAKLESISTGSLLRVTPRLVDEGGQRNV
MLTLVIQDGRQAGTVSQHEPLPQTLNAEVSTQTLLKAGQSLLLGGFVQDEHSEGESKIPLLGDIPLIGKLFRSTQKNSRS
TVRLFLIKAEPAVQS

Sequences:

>Translated_495_residues
MRASKWLGPGLVALTCAQAFAAIPWQSSAPFFLSTRGSKLADVLRDLGANYSVPVVVSKQVDEPFIGAIRSMPPEQALDQ
LARLHKLAWYYDGQAIYVYKAQEVSSQLITPAYLQVSTLISQLQGSGILDRRYCRVRAVPASNAMEVHGVPICLNRVEQL
AKRIDEQKLNHEQNQEIIQLFPLKYATAADGSYSYRGQQVAVPGVVSVLKDMAQGRTLPLKENQGQQPPTDRSLPMFSAD
PRQNAVIVRDRKINMPLYASLIEQFDRKPALIEVSVMIIDVNSQDLSALGIDWSASASIGGNGISFNSAGQQGSDNFSTV
ISNTGGFMVKLNALQQKAKAQILSRPSVVTLDNTQAVLDRNITFYTKLLAEKVAKLESISTGSLLRVTPRLVDEGGQRNV
MLTLVIQDGRQAGTVSQHEPLPQTLNAEVSTQTLLKAGQSLLLGGFVQDEHSEGESKIPLLGDIPLIGKLFRSTQKNSRS
TVRLFLIKAEPAVQS
>Mature_495_residues
MRASKWLGPGLVALTCAQAFAAIPWQSSAPFFLSTRGSKLADVLRDLGANYSVPVVVSKQVDEPFIGAIRSMPPEQALDQ
LARLHKLAWYYDGQAIYVYKAQEVSSQLITPAYLQVSTLISQLQGSGILDRRYCRVRAVPASNAMEVHGVPICLNRVEQL
AKRIDEQKLNHEQNQEIIQLFPLKYATAADGSYSYRGQQVAVPGVVSVLKDMAQGRTLPLKENQGQQPPTDRSLPMFSAD
PRQNAVIVRDRKINMPLYASLIEQFDRKPALIEVSVMIIDVNSQDLSALGIDWSASASIGGNGISFNSAGQQGSDNFSTV
ISNTGGFMVKLNALQQKAKAQILSRPSVVTLDNTQAVLDRNITFYTKLLAEKVAKLESISTGSLLRVTPRLVDEGGQRNV
MLTLVIQDGRQAGTVSQHEPLPQTLNAEVSTQTLLKAGQSLLLGGFVQDEHSEGESKIPLLGDIPLIGKLFRSTQKNSRS
TVRLFLIKAEPAVQS

Specific function: Very likely required for the export process of the yop proteins [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI87082242, Length=419, Percent_Identity=26.9689737470167, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789793, Length=264, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 54036; Mature: 54036

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASKWLGPGLVALTCAQAFAAIPWQSSAPFFLSTRGSKLADVLRDLGANYSVPVVVSKQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECC
VDEPFIGAIRSMPPEQALDQLARLHKLAWYYDGQAIYVYKAQEVSSQLITPAYLQVSTLI
CCCHHHHHHHCCCHHHHHHHHHHHHHHHEEECCEEEEEEEHHHHHHHCCCHHHHHHHHHH
SQLQGSGILDRRYCRVRAVPASNAMEVHGVPICLNRVEQLAKRIDEQKLNHEQNQEIIQL
HHHCCCCCCCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
FPLKYATAADGSYSYRGQQVAVPGVVSVLKDMAQGRTLPLKENQGQQPPTDRSLPMFSAD
CCCCEEECCCCCCCCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
PRQNAVIVRDRKINMPLYASLIEQFDRKPALIEVSVMIIDVNSQDLSALGIDWSASASIG
CCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEECCCCCCCCCCC
GNGISFNSAGQQGSDNFSTVISNTGGFMVKLNALQQKAKAQILSRPSVVTLDNTQAVLDR
CCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCEEEECCCHHHHHC
NITFYTKLLAEKVAKLESISTGSLLRVTPRLVDEGGQRNVMLTLVIQDGRQAGTVSQHEP
CHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCC
LPQTLNAEVSTQTLLKAGQSLLLGGFVQDEHSEGESKIPLLGDIPLIGKLFRSTQKNSRS
CCHHCCCCHHHHHHHHCCCHHEECCEECCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCC
TVRLFLIKAEPAVQS
EEEEEEEECCCCCCC
>Mature Secondary Structure
MRASKWLGPGLVALTCAQAFAAIPWQSSAPFFLSTRGSKLADVLRDLGANYSVPVVVSKQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECC
VDEPFIGAIRSMPPEQALDQLARLHKLAWYYDGQAIYVYKAQEVSSQLITPAYLQVSTLI
CCCHHHHHHHCCCHHHHHHHHHHHHHHHEEECCEEEEEEEHHHHHHHCCCHHHHHHHHHH
SQLQGSGILDRRYCRVRAVPASNAMEVHGVPICLNRVEQLAKRIDEQKLNHEQNQEIIQL
HHHCCCCCCCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
FPLKYATAADGSYSYRGQQVAVPGVVSVLKDMAQGRTLPLKENQGQQPPTDRSLPMFSAD
CCCCEEECCCCCCCCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
PRQNAVIVRDRKINMPLYASLIEQFDRKPALIEVSVMIIDVNSQDLSALGIDWSASASIG
CCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEECCCCCCCCCCC
GNGISFNSAGQQGSDNFSTVISNTGGFMVKLNALQQKAKAQILSRPSVVTLDNTQAVLDR
CCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCEEEECCCHHHHHC
NITFYTKLLAEKVAKLESISTGSLLRVTPRLVDEGGQRNVMLTLVIQDGRQAGTVSQHEP
CHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCC
LPQTLNAEVSTQTLLKAGQSLLLGGFVQDEHSEGESKIPLLGDIPLIGKLFRSTQKNSRS
CCHHCCCCHHHHHHHHCCCHHEECCEECCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCC
TVRLFLIKAEPAVQS
EEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1860816 [H]