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The map label for this gene is prgK [H]

Identifier: 34497875

GI number: 34497875

Start: 2605166

End: 2605894

Strand: Reverse

Name: prgK [H]

Synonym: CV_2420

Alternate gene names: 34497875

Gene position: 2605894-2605166 (Counterclockwise)

Preceding gene: 34497876

Following gene: 34497874

Centisome position: 54.85

GC content: 64.61

Gene sequence:

>729_bases
ATGATGAAGGCTTGCCTGAAAGCGTTGCTGCTGGCCGCGGCGCTGAGCGGTTGCCAGCAAAAGGACCTGCTGAAAGGATT
GGATCAGCAGCAGGCCAACGAGGTGATCGCGGTGTTGCAGCGTCACAATATCGAAGCCGACAAGGCGGACCGTGGCAAAG
CCGGTTTCAGCATCGCCGTGGCGCCTGCGGATTTCGCCGCGGCGGTGGACTGGCTGCGCGCCTACGACCTGCCTTCCAGG
CCGAGGATGGAAGTGGCGCAGATGTTTCCCGCCGATTCGCTGGTCTCTTCGCCGCGGGCTGAGAAAGCTAGGCTCTATTC
CGCGATAGAGCAGCGGCTGGAGCAGTCGCTGCAAACCATGGACGGCATCCTGTCCGCCCGGGTCCACGTCAGCTACGACC
TGGACAGCGGCGAAGCCGGGCGCGCGTCCCAGCCCATGCATATCTCGGCGCTGGCGGTGTACGACCGCGATGTCGACGCC
GCAGCGATGATCAACAACATCAAGCGTTTCCTGAAGAACAGCTTCGCCGAAGTCGACTACGACAACATCTCGGTGGTGTT
GTCGCGCCGCGAAGAAGCGCAGCAGCAGCCTCCCGGCCCAGCGCCGAAAAGCAATGCCGCCTCCCTGTCCTGGCTGATCG
CCGGGATCGGGTTGGCGCTGCTGGCCGGCATCGCCGCCTGGTGGCGGATGAGGCGCGGCTCCCGAGCCGGAGAGCCTCGC
AATGGCTGA

Upstream 100 bases:

>100_bases
TCGCGTTGCAGCAGCGAACCGCCAATTACAACCTCGAGGTTTCGATGATCAGCACGCTGACCCGCAAAACCGTCGGCGCG
GTGGAAAGCTTGCTGCGCTC

Downstream 100 bases:

>100_bases
GCAGGCTGTCCAGCTGCGGGCCCTCCTGTTCGACCCCCTGTCCTACCTGCATCGGGACAGGCTGCGGCTGCCGCCCGCGC
TTGCCGGCGCGGAACAGCGG

Product: cell invasion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MMKACLKALLLAAALSGCQQKDLLKGLDQQQANEVIAVLQRHNIEADKADRGKAGFSIAVAPADFAAAVDWLRAYDLPSR
PRMEVAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTMDGILSARVHVSYDLDSGEAGRASQPMHISALAVYDRDVDA
AAMINNIKRFLKNSFAEVDYDNISVVLSRREEAQQQPPGPAPKSNAASLSWLIAGIGLALLAGIAAWWRMRRGSRAGEPR
NG

Sequences:

>Translated_242_residues
MMKACLKALLLAAALSGCQQKDLLKGLDQQQANEVIAVLQRHNIEADKADRGKAGFSIAVAPADFAAAVDWLRAYDLPSR
PRMEVAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTMDGILSARVHVSYDLDSGEAGRASQPMHISALAVYDRDVDA
AAMINNIKRFLKNSFAEVDYDNISVVLSRREEAQQQPPGPAPKSNAASLSWLIAGIGLALLAGIAAWWRMRRGSRAGEPR
NG
>Mature_242_residues
MMKACLKALLLAAALSGCQQKDLLKGLDQQQANEVIAVLQRHNIEADKADRGKAGFSIAVAPADFAAAVDWLRAYDLPSR
PRMEVAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTMDGILSARVHVSYDLDSGEAGRASQPMHISALAVYDRDVDA
AAMINNIKRFLKNSFAEVDYDNISVVLSRREEAQQQPPGPAPKSNAASLSWLIAGIGLALLAGIAAWWRMRRGSRAGEPR
NG

Specific function: Required for invasion of epithelial cells. Could be involved in protein secretion [H]

COG id: COG4669

COG function: function code U; Type III secretory pathway, lipoprotein EscJ

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yscJ lipoprotein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003282
- InterPro:   IPR006182 [H]

Pfam domain/function: PF01514 YscJ_FliF [H]

EC number: NA

Molecular weight: Translated: 26299; Mature: 26299

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKACLKALLLAAALSGCQQKDLLKGLDQQQANEVIAVLQRHNIEADKADRGKAGFSIAV
CHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
APADFAAAVDWLRAYDLPSRPRMEVAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTM
CCHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DGILSARVHVSYDLDSGEAGRASQPMHISALAVYDRDVDAAAMINNIKRFLKNSFAEVDY
HHHHHHHEEEEEECCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
DNISVVLSRREEAQQQPPGPAPKSNAASLSWLIAGIGLALLAGIAAWWRMRRGSRAGEPR
CHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NG
CC
>Mature Secondary Structure
MMKACLKALLLAAALSGCQQKDLLKGLDQQQANEVIAVLQRHNIEADKADRGKAGFSIAV
CHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
APADFAAAVDWLRAYDLPSRPRMEVAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTM
CCHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DGILSARVHVSYDLDSGEAGRASQPMHISALAVYDRDVDAAAMINNIKRFLKNSFAEVDY
HHHHHHHEEEEEECCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
DNISVVLSRREEAQQQPPGPAPKSNAASLSWLIAGIGLALLAGIAAWWRMRRGSRAGEPR
CHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]