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The map label for this gene is cobC [H]

Identifier: 339905976

GI number: 339905976

Start: 3194682

End: 3195770

Strand: Direct

Name: cobC [H]

Synonym: NA

Alternate gene names: 339905976

Gene position: 3194682-3195770 (Clockwise)

Preceding gene: 238028353

Following gene: 238028355

Centisome position: 81.78

GC content: 76.68

Gene sequence:

>1089_bases
ATGACCGACTCCGTCTTCACGCCGCCCGCGATCACGCACGGCGGCAATCCGCACGACGCGGCGCGCCGCTACGGCATTCC
GGCCGCGCAATGGCTCGATCTCTCGACCGGCATCAACCCGCTCGGCTATCCGGTGCCGCCGGTGCCGGCCGACGCGTGGC
GCCGGCTGCCCGGCGACGATGCCCCGCTCGCCGCGCTGGCCGCCAGCCATTACGGCGCGCCCGACCCCGCGCACGTGCTG
CCGGTGGCCGGCAGCCAGGCGGCGATCCGCGCGCTGCCGGGGCTGCTCGCCCACGGCACGGCCGGCGTGGCGCCGCTCGC
CTACAGCGAATACGCGCCGGCCTTCGCGCGGCACGGCCATGCCATCGCGCCCATCGACGTCGGCGCGACGCGGCTGCCCG
CCGCACTGCGCCACGTGATCGTCGGCAACCCCAACAATCCGACCGCCGAGCGGGTCGATCGCGCGCGGCTGCTGGACTGG
CATGCGCAACTCTCCGCGCGCGGCGGCACGCTGATCGTCGACAGGGCGTTCGCCGACGCAGACGAGTCGAACACGACGCT
CACCGCCAAGATCGACCGCCCGGGCCTCGTCGTGCTGCGCTCGGTCGGCAAGTTCTTCGGGCTGGCGGGCGTGCGCGCCG
GCTTCGTGCTGGCCGCGCCGGCCCTGCTCGCGCGGCTGCGCGCCGAACTCGGCGCGTGGACCGTCAGCGGCCCCGCGCGG
CATGCCGTGCACGCCGCGCTGGCCGATGCGCACTGGCAGCGCGCCACGCGCGCCCGGCTCGCCCGCGACGGCGCCCGGCT
CGCCGCACTGCTCGGCGCGCTGGGGATGAGGGTGCGCGCCACGCCGCTGTTCTGCTGGACCGACGACGCGCGCGCCGCTG
CGCTGCACGACTCGCTCGCGCGGCAGGGTATCTGGACCCGCTTCTTCGCGCATGCGCCGAGCGTGCGGATCGGCCTGCCC
GGCACGAACGCCGAATGGCAGCGGCTCGCGGACGCGCTCGCCGGCTTCGCGGCCGAATCGGCCGCATCGGCACACCCGGC
CGAGCGGCTCGACTCGTCCGCGCCGGCCGGCGGCCGGACGGCGCGCTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: putative threonine-phosphate decarboxylase

Products: NA

Alternate protein names: L-threonine-O-3-phosphate decarboxylase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:
NA

Sequences:

>Translated_362_residues
MTDSVFTPPAITHGGNPHDAARRYGIPAAQWLDLSTGINPLGYPVPPVPADAWRRLPGDDAPLAALAASHYGAPDPAHVL
PVAGSQAAIRALPGLLAHGTAGVAPLAYSEYAPAFARHGHAIAPIDVGATRLPAALRHVIVGNPNNPTAERVDRARLLDW
HAQLSARGGTLIVDRAFADADESNTTLTAKIDRPGLVVLRSVGKFFGLAGVRAGFVLAAPALLARLRAELGAWTVSGPAR
HAVHAALADAHWQRATRARLARDGARLAALLGALGMRVRATPLFCWTDDARAAALHDSLARQGIWTRFFAHAPSVRIGLP
GTNAEWQRLADALAGFAAESAASAHPAERLDSSAPAGGRTAR
>Mature_361_residues
TDSVFTPPAITHGGNPHDAARRYGIPAAQWLDLSTGINPLGYPVPPVPADAWRRLPGDDAPLAALAASHYGAPDPAHVLP
VAGSQAAIRALPGLLAHGTAGVAPLAYSEYAPAFARHGHAIAPIDVGATRLPAALRHVIVGNPNNPTAERVDRARLLDWH
AQLSARGGTLIVDRAFADADESNTTLTAKIDRPGLVVLRSVGKFFGLAGVRAGFVLAAPALLARLRAELGAWTVSGPARH
AVHAALADAHWQRATRARLARDGARLAALLGALGMRVRATPLFCWTDDARAAALHDSLARQGIWTRFFAHAPSVRIGLPG
TNAEWQRLADALAGFAAESAASAHPAERLDSSAPAGGRTAR

Specific function: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005860
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =4.1.1.81 [H]

Molecular weight: Translated: 37768; Mature: 37637

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSVFTPPAITHGGNPHDAARRYGIPAAQWLDLSTGINPLGYPVPPVPADAWRRLPGDD
CCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHEEHHCCCCCCCCCCCCCCHHHHHCCCCCC
APLAALAASHYGAPDPAHVLPVAGSQAAIRALPGLLAHGTAGVAPLAYSEYAPAFARHGH
CCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHCCC
AIAPIDVGATRLPAALRHVIVGNPNNPTAERVDRARLLDWHAQLSARGGTLIVDRAFADA
EEEECCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
DESNTTLTAKIDRPGLVVLRSVGKFFGLAGVRAGFVLAAPALLARLRAELGAWTVSGPAR
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHH
HAVHAALADAHWQRATRARLARDGARLAALLGALGMRVRATPLFCWTDDARAAALHDSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEECCCCHHHHHHHHHH
RQGIWTRFFAHAPSVRIGLPGTNAEWQRLADALAGFAAESAASAHPAERLDSSAPAGGRT
HHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCC
AR
CC
>Mature Secondary Structure 
TDSVFTPPAITHGGNPHDAARRYGIPAAQWLDLSTGINPLGYPVPPVPADAWRRLPGDD
CCCCCCCCCCCCCCCHHHHHHHCCCCHHHHEEHHCCCCCCCCCCCCCCHHHHHCCCCCC
APLAALAASHYGAPDPAHVLPVAGSQAAIRALPGLLAHGTAGVAPLAYSEYAPAFARHGH
CCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHCCC
AIAPIDVGATRLPAALRHVIVGNPNNPTAERVDRARLLDWHAQLSARGGTLIVDRAFADA
EEEECCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
DESNTTLTAKIDRPGLVVLRSVGKFFGLAGVRAGFVLAAPALLARLRAELGAWTVSGPAR
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHH
HAVHAALADAHWQRATRARLARDGARLAALLGALGMRVRATPLFCWTDDARAAALHDSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEECCCCHHHHHHHHHH
RQGIWTRFFAHAPSVRIGLPGTNAEWQRLADALAGFAAESAASAHPAERLDSSAPAGGRT
HHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCC
AR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]