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The map label for this gene is ttuB [H]

Identifier: 339717981

GI number: 339717981

Start: 2458238

End: 2459530

Strand: Reverse

Name: ttuB [H]

Synonym: NA

Alternate gene names: 339717981

Gene position: 2459530-2458238 (Counterclockwise)

Preceding gene: 238025305

Following gene: 238025303

Centisome position: 86.99

GC content: 68.06

Gene sequence:

>1293_bases
ATGTCGGCCGTATCGCCCGCCCTGCGGGTCTCGGAGGAGGCCGCCTATCGCAAGGTCGCATGGCGGCTCATGCCCTTGCT
GCTGTTCTGCTATCTGGTGTCGTACCTCGACCGCGTCAACGTCGGCTTCGCGAAGCTGCAGATGGCCGGCGATCTAGGCC
TGTCGGACGCGGCCTACGGGCTCGGCGCCGGCATCTTCTTCCTCGGCTATTTCCTCTTCGAGGTGCCGAGCAACCTGATC
CTGCACCGCGTCGGCGCGCGCGTGTGGATCGCGCGGATCATGGTGACCTGGGGTGCGGTGTCGGCGCTGACGATGTTCGT
CACGACGCCGGCGGCCTTCTACGCGATGCGCTTGCTGCTCGGCGCCGCGGAGGCCGGCTTCTTTCCGGGCGTGATCCTCT
ACCTGACCTACTGGTATCCGGCCCGGCGGCGCGGGCGGATCACGACGCTGTTCATGACGGCCGTCGCGCTGTCGGGTGTC
GTTGGCGGCCCGATCTCCGGCTACATCCTGAAGGCGTTCGACGGCATCCACGGCTGGCACGGCTGGCAGTGGCTGTATCT
GCTCGAAGGGCTGCCGTCGATCGTCGCGGGCCTGCTCGTGTATGCGCGGCTCGACGATCGCATCGCGCATGCGAAGTGGC
TCAGCGAAGACGAGCGCGCGCTGCTCGAACGCCACGTGAATGCCGAGGAAGCGGTCAAGTCGCAGCTGTCGCTCGGCGCG
GTGTTCGTGAATCCGCGGGTGTGGCTGATGTGCGCGATCTACTTTTCGTTCGTGATCGGCCTGTACGGCGTCGGATTCTG
GCTGCCGACGCTCATTCATGCGACGGGCGTGGCCGATCCACTGCGGATCGGTCTGCTGTCGACGGTGCCGTATGCGCTGG
CAGTGGTCGCGATGACGGCTGTCGCGCGCAGCTCCGACCGGCATCGCGAACGCCGCTGGCATCTCGCGCTGCCCGGCGCG
ATGGGCACCATCGGCCTGGTGCTGGCGGTCGGCTGGGCGCATCAGACCGGGCTGGCCGTCGCGGCGCTGGCGCTCGCGAC
GGCGGGCATCCTGACCGCGATTCCGCTGTTCTGGAGCCTGCCGACCGCGTTCCTGGGCGGCACCGCGGCCGCGGCCGGGA
TCGCGGTGATCAATTCGATCGGCAATCTCGCCGGCTTCCTCGGCCCGTACCTGATGGGACTGCTCGCGCAATGGACCGCG
TCGAACGATGCCGGTCTCTACCTGATGGCAGGCTGCATGACGCTGGGCGGCCTGCTCGCGCTGTCGCTGCCGAAGACGCT
GGTCAACCGCTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:
NA

Sequences:

>Translated_430_residues
MSAVSPALRVSEEAAYRKVAWRLMPLLLFCYLVSYLDRVNVGFAKLQMAGDLGLSDAAYGLGAGIFFLGYFLFEVPSNLI
LHRVGARVWIARIMVTWGAVSALTMFVTTPAAFYAMRLLLGAAEAGFFPGVILYLTYWYPARRRGRITTLFMTAVALSGV
VGGPISGYILKAFDGIHGWHGWQWLYLLEGLPSIVAGLLVYARLDDRIAHAKWLSEDERALLERHVNAEEAVKSQLSLGA
VFVNPRVWLMCAIYFSFVIGLYGVGFWLPTLIHATGVADPLRIGLLSTVPYALAVVAMTAVARSSDRHRERRWHLALPGA
MGTIGLVLAVGWAHQTGLAVAALALATAGILTAIPLFWSLPTAFLGGTAAAAGIAVINSIGNLAGFLGPYLMGLLAQWTA
SNDAGLYLMAGCMTLGGLLALSLPKTLVNR
>Mature_429_residues
SAVSPALRVSEEAAYRKVAWRLMPLLLFCYLVSYLDRVNVGFAKLQMAGDLGLSDAAYGLGAGIFFLGYFLFEVPSNLIL
HRVGARVWIARIMVTWGAVSALTMFVTTPAAFYAMRLLLGAAEAGFFPGVILYLTYWYPARRRGRITTLFMTAVALSGVV
GGPISGYILKAFDGIHGWHGWQWLYLLEGLPSIVAGLLVYARLDDRIAHAKWLSEDERALLERHVNAEEAVKSQLSLGAV
FVNPRVWLMCAIYFSFVIGLYGVGFWLPTLIHATGVADPLRIGLLSTVPYALAVVAMTAVARSSDRHRERRWHLALPGAM
GTIGLVLAVGWAHQTGLAVAALALATAGILTAIPLFWSLPTAFLGGTAAAAGIAVINSIGNLAGFLGPYLMGLLAQWTAS
NDAGLYLMAGCMTLGGLLALSLPKTLVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=419, Percent_Identity=37.708830548926, Blast_Score=257, Evalue=8e-70,
Organism=Escherichia coli, GI2367379, Length=435, Percent_Identity=24.1379310344828, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789515, Length=446, Percent_Identity=22.1973094170404, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789152, Length=176, Percent_Identity=28.4090909090909, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=326, Percent_Identity=23.6196319018405, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322025, Length=204, Percent_Identity=26.9607843137255, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321502, Length=346, Percent_Identity=20.8092485549133, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319876, Length=218, Percent_Identity=25.2293577981651, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=250, Percent_Identity=23.6, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324410, Length=151, Percent_Identity=24.5033112582781, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323032, Length=225, Percent_Identity=26.2222222222222, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584153, Length=364, Percent_Identity=22.5274725274725, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46276; Mature: 46145

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCC
>Mature Secondary Structure 
SAVSPALRVSEEAAYRKVAWRLMPLLLFCYLVSYLDRVNVGFAKLQMAGDLGLSDAAYG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHH
LGAGIFFLGYFLFEVPSNLILHRVGARVWIARIMVTWGAVSALTMFVTTPAAFYAMRLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAEAGFFPGVILYLTYWYPARRRGRITTLFMTAVALSGVVGGPISGYILKAFDGIHGWH
HHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
GWQWLYLLEGLPSIVAGLLVYARLDDRIAHAKWLSEDERALLERHVNAEEAVKSQLSLGA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCE
VFVNPRVWLMCAIYFSFVIGLYGVGFWLPTLIHATGVADPLRIGLLSTVPYALAVVAMTA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VARSSDRHRERRWHLALPGAMGTIGLVLAVGWAHQTGLAVAALALATAGILTAIPLFWSL
HHHCCHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PTAFLGGTAAAAGIAVINSIGNLAGFLGPYLMGLLAQWTASNDAGLYLMAGCMTLGGLLA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LSLPKTLVNR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]