Click here to switch to the map view.

The map label for this gene is ppx [H]

Identifier: 33863594

GI number: 33863594

Start: 1411449

End: 1413149

Strand: Reverse

Name: ppx [H]

Synonym: PMT1327

Alternate gene names: 33863594

Gene position: 1413149-1411449 (Counterclockwise)

Preceding gene: 33863597

Following gene: 33863588

Centisome position: 58.62

GC content: 54.09

Gene sequence:

>1701_bases
ATGGCAAAGTGGTCTCGTTCCAGGCTCCTGTACTTCATGCCAGGTGTCGAGCCATTGCCTTTCGGTGTGGTTGATGTCGA
GCAGGAGGAGGCCAGGTACGTCAGTGCTGGTCAGCTCCGTTCTGAGCGAGAGCTCCGCAACGTTGCCGCGATTGATATTG
GAACCAATTCCACCCATCTCTTGGTGGCGTCGGTTGATCCTTCTCTGCATACCTTCAGCGTTGATCTTGCAGAGAAATCA
ACCACCAGGCTTGGTGAGCGAGACCCTGACTCTGGAGAGCTCACGGGTCCTGCTATGGAGCGGGTATTTGAGACACTCAA
ACGTTTTAAGGAGCTAGCCGCCAGCCATCAGGTGGAGCAGGTGGTTGCGTCGGCGACTAGCGCAGTACGTGAAGCTTCAA
ATGGGCGGGATTTTTTGCAACGGATTCAGGATCAGCTTGGCCTTGAGGTGGATCTGTTGAGCGGTGCTGAGGAAGCACGA
CTGATCTATTTGGGTGTTTTGTCTGGCATGCCTTTTGGGGAGTGTCCCCATCTTTTGCTCGATATCGGTGGCGGTTCCAC
AGAACTCATCCTCGCGGATGGTCGCGATGCTCGGGCTCTGACAAGCACGCGGGTTGGTGCGGTTCGGCTACAGAGGGATT
TTGTCAAGCATGAACCAATCCCCCCTCAACGGCGTTCCTTTTTGCAGACATTTATTCAGGGTTCTTTAGAGCCAGCTGTT
GATAAGGTCTGCCGTCGCATCAAGCCTGGGGAGAGCCCTGTGATGGTTGCCACCAGTGGAACCGCCATGGCCATCGGTGC
TTTGTTGGCTAGCGAAGACGATCGCCCTCCGTTGAGATTGCATGGCTATCGAATCACACGGCAGCAGCTTGATGGCCTGG
TTGAGAAGCTGATAGCGATGACGCCTGAGCAGCGTCGCATCCAGACGCCGATTAATGATCGCCGTGCCGAAATCATCGTT
CCGGGTGCGCTGATTCTTCAAACTGCCATGCAGATGCTCTCTGCTGATGAGCTGGTGCTGAGTGAAAGGGCTCTGAGGGA
GGGGTTGATCGTTGATTGGATGCTGCGACATGGCCTACTGGAGGATCGCTTTAGTTTTCAGAGCAGTATTCGTCAGCGCA
CCGTGATTCATCAGGTGCAGCGTTTTGCAGTGAATCACCGCCGTGCAGAGCGTGTAGCCAGCCATGCACTCAGCCTTTAC
GACCACACACATGGTGTTCTTCATCAAGATGATGGAGGTGGTCGGGATCTGCTTTGGGCATCGGCCATGTTGCATGCCTG
TGGTCAGCACATCAATCTCAGTGCTTATCACAAGCATTCCTGGTATCTCATTCGTCATGGCGAGTTGCTCGGCTATTCGG
AAGCGGAGCATTTGATGGTTGCGGCTATTGCGCGCTATCACCGCCGCAGTCTTCCCAAGAAGCGTCATCTGGAATGGCAG
GCTTTAGCCACCCGGGAGCATCGTCGCCTCGTTGCCGAGATGGCTTTGTTGCTGCGATTAGCAGCAGCCATTGATCGCCG
TCCTGAGCCAGTGGTGGCTGCAATAAGAGTGAAGTCCGCTGATGATGATCAGATTGTCTTTGAACTAGTGCCGGAAGGAT
TGAATCAGAATCTCAGCCTTGAACAATGGAGCTTGAAGAGCTGTGCTTCGGTTGTGAAAGAAGCAAGCGGCGTAACCATG
AAAGTTGTCGTTAAGGAGTGA

Upstream 100 bases:

>100_bases
AGCTCTAGCCATTGCCTTAAGCCATTGGAGAAGGATCTGCTGGTCACGGGTTTCTGGGTTTGAAGAACCCTAGGGAGGGA
CCTCCAGACATCGTTGGCTG

Downstream 100 bases:

>100_bases
ACTTAGTTCAGTATTAGGTTGTTGTTGGATAATTGATGCCAGCGGATCTTTCTAATTGCACCCAGAGCAGTAGGCGGTTT
TCGATTATGAGTTATATGAA

Product: exopolyphosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MAKWSRSRLLYFMPGVEPLPFGVVDVEQEEARYVSAGQLRSERELRNVAAIDIGTNSTHLLVASVDPSLHTFSVDLAEKS
TTRLGERDPDSGELTGPAMERVFETLKRFKELAASHQVEQVVASATSAVREASNGRDFLQRIQDQLGLEVDLLSGAEEAR
LIYLGVLSGMPFGECPHLLLDIGGGSTELILADGRDARALTSTRVGAVRLQRDFVKHEPIPPQRRSFLQTFIQGSLEPAV
DKVCRRIKPGESPVMVATSGTAMAIGALLASEDDRPPLRLHGYRITRQQLDGLVEKLIAMTPEQRRIQTPINDRRAEIIV
PGALILQTAMQMLSADELVLSERALREGLIVDWMLRHGLLEDRFSFQSSIRQRTVIHQVQRFAVNHRRAERVASHALSLY
DHTHGVLHQDDGGGRDLLWASAMLHACGQHINLSAYHKHSWYLIRHGELLGYSEAEHLMVAAIARYHRRSLPKKRHLEWQ
ALATREHRRLVAEMALLLRLAAAIDRRPEPVVAAIRVKSADDDQIVFELVPEGLNQNLSLEQWSLKSCASVVKEASGVTM
KVVVKE

Sequences:

>Translated_566_residues
MAKWSRSRLLYFMPGVEPLPFGVVDVEQEEARYVSAGQLRSERELRNVAAIDIGTNSTHLLVASVDPSLHTFSVDLAEKS
TTRLGERDPDSGELTGPAMERVFETLKRFKELAASHQVEQVVASATSAVREASNGRDFLQRIQDQLGLEVDLLSGAEEAR
LIYLGVLSGMPFGECPHLLLDIGGGSTELILADGRDARALTSTRVGAVRLQRDFVKHEPIPPQRRSFLQTFIQGSLEPAV
DKVCRRIKPGESPVMVATSGTAMAIGALLASEDDRPPLRLHGYRITRQQLDGLVEKLIAMTPEQRRIQTPINDRRAEIIV
PGALILQTAMQMLSADELVLSERALREGLIVDWMLRHGLLEDRFSFQSSIRQRTVIHQVQRFAVNHRRAERVASHALSLY
DHTHGVLHQDDGGGRDLLWASAMLHACGQHINLSAYHKHSWYLIRHGELLGYSEAEHLMVAAIARYHRRSLPKKRHLEWQ
ALATREHRRLVAEMALLLRLAAAIDRRPEPVVAAIRVKSADDDQIVFELVPEGLNQNLSLEQWSLKSCASVVKEASGVTM
KVVVKE
>Mature_565_residues
AKWSRSRLLYFMPGVEPLPFGVVDVEQEEARYVSAGQLRSERELRNVAAIDIGTNSTHLLVASVDPSLHTFSVDLAEKST
TRLGERDPDSGELTGPAMERVFETLKRFKELAASHQVEQVVASATSAVREASNGRDFLQRIQDQLGLEVDLLSGAEEARL
IYLGVLSGMPFGECPHLLLDIGGGSTELILADGRDARALTSTRVGAVRLQRDFVKHEPIPPQRRSFLQTFIQGSLEPAVD
KVCRRIKPGESPVMVATSGTAMAIGALLASEDDRPPLRLHGYRITRQQLDGLVEKLIAMTPEQRRIQTPINDRRAEIIVP
GALILQTAMQMLSADELVLSERALREGLIVDWMLRHGLLEDRFSFQSSIRQRTVIHQVQRFAVNHRRAERVASHALSLYD
HTHGVLHQDDGGGRDLLWASAMLHACGQHINLSAYHKHSWYLIRHGELLGYSEAEHLMVAAIARYHRRSLPKKRHLEWQA
LATREHRRLVAEMALLLRLAAAIDRRPEPVVAAIRVKSADDDQIVFELVPEGLNQNLSLEQWSLKSCASVVKEASGVTMK
VVVKE

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=441, Percent_Identity=27.891156462585, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI48994966, Length=427, Percent_Identity=28.5714285714286, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 63178; Mature: 63047

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKWSRSRLLYFMPGVEPLPFGVVDVEQEEARYVSAGQLRSERELRNVAAIDIGTNSTHL
CCCCCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCEE
LVASVDPSLHTFSVDLAEKSTTRLGERDPDSGELTGPAMERVFETLKRFKELAASHQVEQ
EEEECCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVASATSAVREASNGRDFLQRIQDQLGLEVDLLSGAEEARLIYLGVLSGMPFGECPHLLL
HHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEE
DIGGGSTELILADGRDARALTSTRVGAVRLQRDFVKHEPIPPQRRSFLQTFIQGSLEPAV
ECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHH
DKVCRRIKPGESPVMVATSGTAMAIGALLASEDDRPPLRLHGYRITRQQLDGLVEKLIAM
HHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCEEEECEEECHHHHHHHHHHHHHC
TPEQRRIQTPINDRRAEIIVPGALILQTAMQMLSADELVLSERALREGLIVDWMLRHGLL
CCCHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHH
EDRFSFQSSIRQRTVIHQVQRFAVNHRRAERVASHALSLYDHTHGVLHQDDGGGRDLLWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHH
SAMLHACGQHINLSAYHKHSWYLIRHGELLGYSEAEHLMVAAIARYHRRSLPKKRHLEWQ
HHHHHHCCCCCCEEEEECCCEEEEECCCEECCCHHHHHHHHHHHHHHHHCCCHHHCCCHH
ALATREHRRLVAEMALLLRLAAAIDRRPEPVVAAIRVKSADDDQIVFELVPEGLNQNLSL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHCCHHHCCCCCCC
EQWSLKSCASVVKEASGVTMKVVVKE
HHHHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure 
AKWSRSRLLYFMPGVEPLPFGVVDVEQEEARYVSAGQLRSERELRNVAAIDIGTNSTHL
CCCCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCEE
LVASVDPSLHTFSVDLAEKSTTRLGERDPDSGELTGPAMERVFETLKRFKELAASHQVEQ
EEEECCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVASATSAVREASNGRDFLQRIQDQLGLEVDLLSGAEEARLIYLGVLSGMPFGECPHLLL
HHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEE
DIGGGSTELILADGRDARALTSTRVGAVRLQRDFVKHEPIPPQRRSFLQTFIQGSLEPAV
ECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHH
DKVCRRIKPGESPVMVATSGTAMAIGALLASEDDRPPLRLHGYRITRQQLDGLVEKLIAM
HHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCEEEECEEECHHHHHHHHHHHHHC
TPEQRRIQTPINDRRAEIIVPGALILQTAMQMLSADELVLSERALREGLIVDWMLRHGLL
CCCHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHH
EDRFSFQSSIRQRTVIHQVQRFAVNHRRAERVASHALSLYDHTHGVLHQDDGGGRDLLWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHH
SAMLHACGQHINLSAYHKHSWYLIRHGELLGYSEAEHLMVAAIARYHRRSLPKKRHLEWQ
HHHHHHCCCCCCEEEEECCCEEEEECCCEECCCHHHHHHHHHHHHHHHHCCCHHHCCCHH
ALATREHRRLVAEMALLLRLAAAIDRRPEPVVAAIRVKSADDDQIVFELVPEGLNQNLSL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHCCHHHCCCCCCC
EQWSLKSCASVVKEASGVTMKVVVKE
HHHHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]