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The map label for this gene is 33863519

Identifier: 33863519

GI number: 33863519

Start: 1339306

End: 1340697

Strand: Reverse

Name: 33863519

Synonym: PMT1251

Alternate gene names: NA

Gene position: 1340697-1339306 (Counterclockwise)

Preceding gene: 33863522

Following gene: 33863518

Centisome position: 55.61

GC content: 55.24

Gene sequence:

>1392_bases
TTGAGCTTTGATCCCCTGTTCAGCCTGATCAGGCGATACACCCGTGAGCCGCTTTGGAAAGTCGGACTGGCTTTCGTATC
ACTGATGTTTGCGGTTTTGATTTGGTTTGTGGGGTTGCAAGACAGCTTCAGCAGGCCGTCAGTGACCCCAACCATCTCCA
TGCAGCAACAGGAGATGGCTTTGCTTGCTGATCAGGCCGTCCCTGCAGCCATTAGGCCTCTGCTTGTGGGTGAGGATCCA
ACATTGGCTTTGCAAGAAGCTCTCGGTGAGATCCCTCTCAGTCAGATGAATGACCGCCAGAGGCTGTTGCTCGCCGGACT
CCAATCTTCAGAGGCAGAACGTCGTGAGCTCCTGGCTGCTTCAGTGCAGTCACCGTTACTGATCCCTCTAGAGCAGGCGC
TACTGGCTAGTAAGCAAGAAGGGGGCTTGTCACTTGCTGATCGTGAGGCGCTTGGCTCATTAAGCGGGGACCCTTTGCTT
CAGCAGGTTGGTTGCTTTGCTCTTGGCGGGGATCGCGATGACTGCGTGAATCCCCGTGTCGCATCGAGCATGGCTTTGCG
GCTGGTCTTGAGCGTGGTGTTACCGGCGGCGGCTCTACTTGCCGGTACTGCGCTTTTGTTGCGTCATCTTTGGATGTTGT
TGCGCAAGTCTGTTGCTCCCTGGCCACCGCTTCAGGCCTTACCACTTTCCTTAACGGACATGGTGCTCCTGATTGCCTGT
GGATTTGTGGTCTTGGGTGAGGTGATTGCTCCCGCTTTCGTGGCTCCGCTGAGTGCCTTGATGACGAGGGGGATGGACAG
CCCCTTGAGCAAAGCGTTGACAGTGGTGATTGGCTACGGCGCTTTGGCACTACCGCCATTGTTGATTCTGCGTCAGCAGC
TGCGCAGTCTGCAGGCAACTGATCGGCCCGTTGATGGATGGTTGCAGTGGCGTCTGCAGCCTTGGGGTTCAGCGTTGCTG
AAGGCAGGTCGAGGCTGGTTGATGGTGATGCCGTTGGTTCTCTTGACTGGATGGCTGATGGGATTGCTGTTGGGGGATCA
AGGGGGAAGTAACCCCTTATTGGAACTGGTACTGCGCAGCAAGGATCCATTGGCCTTGATGTTGCTAGCCACCACCGCTG
TGATTCTGGCGCCTCTCTTTGAGGAGTTGGTTTTTCGTGGTGCGCTTCTGCCTGTATTGGCGAAATCTTTTGGCCCGCTA
TGGGGTGTGGTAACTAGCGCGTTGGTGTTTGGTGTGGCTCACCTGAGTGTTGGTGAATTACCACCGCTGTTTGTGTTGGG
CTTGGGACTCGGTCTATTAAGGCTTAGTTCAGGGCGTCTTTTGCCTTGCGTGCTGATGCATGCCCTCTGGAATGGGGTTA
CTTTCATCAATCTTTTGCTGCTTGGCGGATAA

Upstream 100 bases:

>100_bases
TATGGGATGGTTGTCGGAGATGCCCTTGAGGGAGTGTTGAACAGCTGTCAGCGCGCTGTGCTGCGGCCAGCGAGAATCAG
TTTCAATTGATGCCTGGTCG

Downstream 100 bases:

>100_bases
CTGAACTCTTCAATCAGCCTTGATTGTTAGCGACTTAGCCTTGCGGAGGCCTATTGAGGGTGGTTCACTGATTTATTAGA
GTGGCTTATTAGGTGGTTGC

Product: membrane-associated protease

Products: NA

Alternate protein names: Membrane-Associated Protease; Metal-Dependent Membrane Protease; Membrane Associated Protease; CAAX Amino Terminal Protease Family; Caax Amino Terminal Protease Family Protein; Membrane Associated Protease-Like; CAAX Amino Protease; CAAX Amino Terminal Protease Family Protein

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSFDPLFSLIRRYTREPLWKVGLAFVSLMFAVLIWFVGLQDSFSRPSVTPTISMQQQEMALLADQAVPAAIRPLLVGEDP
TLALQEALGEIPLSQMNDRQRLLLAGLQSSEAERRELLAASVQSPLLIPLEQALLASKQEGGLSLADREALGSLSGDPLL
QQVGCFALGGDRDDCVNPRVASSMALRLVLSVVLPAAALLAGTALLLRHLWMLLRKSVAPWPPLQALPLSLTDMVLLIAC
GFVVLGEVIAPAFVAPLSALMTRGMDSPLSKALTVVIGYGALALPPLLILRQQLRSLQATDRPVDGWLQWRLQPWGSALL
KAGRGWLMVMPLVLLTGWLMGLLLGDQGGSNPLLELVLRSKDPLALMLLATTAVILAPLFEELVFRGALLPVLAKSFGPL
WGVVTSALVFGVAHLSVGELPPLFVLGLGLGLLRLSSGRLLPCVLMHALWNGVTFINLLLLGG

Sequences:

>Translated_463_residues
MSFDPLFSLIRRYTREPLWKVGLAFVSLMFAVLIWFVGLQDSFSRPSVTPTISMQQQEMALLADQAVPAAIRPLLVGEDP
TLALQEALGEIPLSQMNDRQRLLLAGLQSSEAERRELLAASVQSPLLIPLEQALLASKQEGGLSLADREALGSLSGDPLL
QQVGCFALGGDRDDCVNPRVASSMALRLVLSVVLPAAALLAGTALLLRHLWMLLRKSVAPWPPLQALPLSLTDMVLLIAC
GFVVLGEVIAPAFVAPLSALMTRGMDSPLSKALTVVIGYGALALPPLLILRQQLRSLQATDRPVDGWLQWRLQPWGSALL
KAGRGWLMVMPLVLLTGWLMGLLLGDQGGSNPLLELVLRSKDPLALMLLATTAVILAPLFEELVFRGALLPVLAKSFGPL
WGVVTSALVFGVAHLSVGELPPLFVLGLGLGLLRLSSGRLLPCVLMHALWNGVTFINLLLLGG
>Mature_462_residues
SFDPLFSLIRRYTREPLWKVGLAFVSLMFAVLIWFVGLQDSFSRPSVTPTISMQQQEMALLADQAVPAAIRPLLVGEDPT
LALQEALGEIPLSQMNDRQRLLLAGLQSSEAERRELLAASVQSPLLIPLEQALLASKQEGGLSLADREALGSLSGDPLLQ
QVGCFALGGDRDDCVNPRVASSMALRLVLSVVLPAAALLAGTALLLRHLWMLLRKSVAPWPPLQALPLSLTDMVLLIACG
FVVLGEVIAPAFVAPLSALMTRGMDSPLSKALTVVIGYGALALPPLLILRQQLRSLQATDRPVDGWLQWRLQPWGSALLK
AGRGWLMVMPLVLLTGWLMGLLLGDQGGSNPLLELVLRSKDPLALMLLATTAVILAPLFEELVFRGALLPVLAKSFGPLW
GVVTSALVFGVAHLSVGELPPLFVLGLGLGLLRLSSGRLLPCVLMHALWNGVTFINLLLLGG

Specific function: Unknown

COG id: COG1266

COG function: function code R; Predicted metal-dependent membrane protease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49670; Mature: 49539

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDPLFSLIRRYTREPLWKVGLAFVSLMFAVLIWFVGLQDSFSRPSVTPTISMQQQEMA
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECHHHHHHH
LLADQAVPAAIRPLLVGEDPTLALQEALGEIPLSQMNDRQRLLLAGLQSSEAERRELLAA
HHHHHCCHHHHCCCEECCCCHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCHHHHHHHHHH
SVQSPLLIPLEQALLASKQEGGLSLADREALGSLSGDPLLQQVGCFALGGDRDDCVNPRV
HHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHCCHHCCCCCCCCCCCHH
ASSMALRLVLSVVLPAAALLAGTALLLRHLWMLLRKSVAPWPPLQALPLSLTDMVLLIAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHH
GFVVLGEVIAPAFVAPLSALMTRGMDSPLSKALTVVIGYGALALPPLLILRQQLRSLQAT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
DRPVDGWLQWRLQPWGSALLKAGRGWLMVMPLVLLTGWLMGLLLGDQGGSNPLLELVLRS
CCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
KDPLALMLLATTAVILAPLFEELVFRGALLPVLAKSFGPLWGVVTSALVFGVAHLSVGEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
PPLFVLGLGLGLLRLSSGRLLPCVLMHALWNGVTFINLLLLGG
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFDPLFSLIRRYTREPLWKVGLAFVSLMFAVLIWFVGLQDSFSRPSVTPTISMQQQEMA
CCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECHHHHHHH
LLADQAVPAAIRPLLVGEDPTLALQEALGEIPLSQMNDRQRLLLAGLQSSEAERRELLAA
HHHHHCCHHHHCCCEECCCCHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCHHHHHHHHHH
SVQSPLLIPLEQALLASKQEGGLSLADREALGSLSGDPLLQQVGCFALGGDRDDCVNPRV
HHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHCCHHCCCCCCCCCCCHH
ASSMALRLVLSVVLPAAALLAGTALLLRHLWMLLRKSVAPWPPLQALPLSLTDMVLLIAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHH
GFVVLGEVIAPAFVAPLSALMTRGMDSPLSKALTVVIGYGALALPPLLILRQQLRSLQAT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
DRPVDGWLQWRLQPWGSALLKAGRGWLMVMPLVLLTGWLMGLLLGDQGGSNPLLELVLRS
CCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
KDPLALMLLATTAVILAPLFEELVFRGALLPVLAKSFGPLWGVVTSALVFGVAHLSVGEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
PPLFVLGLGLGLLRLSSGRLLPCVLMHALWNGVTFINLLLLGG
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA