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The map label for this gene is 33863456

Identifier: 33863456

GI number: 33863456

Start: 1276617

End: 1277189

Strand: Reverse

Name: 33863456

Synonym: PMT1186

Alternate gene names: NA

Gene position: 1277189-1276617 (Counterclockwise)

Preceding gene: 33863457

Following gene: 33863451

Centisome position: 52.98

GC content: 46.95

Gene sequence:

>573_bases
ATGCCTTTCCCTCAAAACGTTCCAGATGTCACCTTCAAGACTCGCGTGCGCGATGAATCTGTGCCCGGGTCTAATCCATT
CCGCTGGCAAGACCTGACTAGTGCTGAAATCTTTAAGGGGCGCAAGGTGGTGGTGTTAGCCCTGCCAGGAGCTTTTACGC
CTACGTGCTCATCCAATCATTTGCCACGTTATGAGGAGTTGCATGCAGAACTTGTTGCCCAAGGTGTTGATCAGATTGTC
TGTCTTTCAGTGAATGATGCTTTTGTAATGTTCCAGTGGAGCAAACATTTGGGTACCAAGAATATCTTTATGCTCCCTGA
TGGGAATGGAGAGTTCACTCGTAAAATGGGCATGCTTGTTGAGAAATCCAACCTAGGTTTTGGTTTGCGTTCCTGGCGCT
ATTCGATGCTAGTGAATGATTGTAATATTGAAAAGATGTTTGTTGAGCCTGGCTTTAGTGATAATGCTGATGGTGACCCG
TTTGAGGTCTCAGATGCTGATACGATGCTTGCTTACATGAAGGGTGTGCAATCGGCTGGTGTTAGTTCCCCGTGCCGTGA
GTTTCAGGGTTAA

Upstream 100 bases:

>100_bases
GATCGATTCACGCCGTCGGCGATAGGTTTCAACAATTTGATTATTTGACAAGATTAGATGAGGTGTATGAGATTTTGTTT
GCATCAACATCAGCCTTGCA

Downstream 100 bases:

>100_bases
ACCCTTCACTTCTCACACTCTTGCCTGTTCATTAAATATAAAACTGATTATCTGTTTTCCTGCTTCACTCTATATCTTAC
GTAACAAGTAGCAATCCTCT

Product: alkyl hydroperoxide reductase/thiol specific antioxidant

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MPFPQNVPDVTFKTRVRDESVPGSNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNHLPRYEELHAELVAQGVDQIV
CLSVNDAFVMFQWSKHLGTKNIFMLPDGNGEFTRKMGMLVEKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADGDP
FEVSDADTMLAYMKGVQSAGVSSPCREFQG

Sequences:

>Translated_190_residues
MPFPQNVPDVTFKTRVRDESVPGSNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNHLPRYEELHAELVAQGVDQIV
CLSVNDAFVMFQWSKHLGTKNIFMLPDGNGEFTRKMGMLVEKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADGDP
FEVSDADTMLAYMKGVQSAGVSSPCREFQG
>Mature_189_residues
PFPQNVPDVTFKTRVRDESVPGSNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNHLPRYEELHAELVAQGVDQIVC
LSVNDAFVMFQWSKHLGTKNIFMLPDGNGEFTRKMGMLVEKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADGDPF
EVSDADTMLAYMKGVQSAGVSSPCREFQG

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=142, Percent_Identity=38.7323943661972, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI78706776, Length=121, Percent_Identity=42.1487603305785, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI78709078, Length=121, Percent_Identity=42.1487603305785, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21198; Mature: 21067

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFPQNVPDVTFKTRVRDESVPGSNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNH
CCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCHHHHHCCCEEEEEEECCCCCCCCCCCC
LPRYEELHAELVAQGVDQIVCLSVNDAFVMFQWSKHLGTKNIFMLPDGNGEFTRKMGMLV
CCCHHHHHHHHHHCCCCEEEEEEECCEEEEEEEHHHCCCCEEEEEECCCCHHHHHHCCEE
EKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADGDPFEVSDADTMLAYMKGVQSAG
EECCCCCCHHHEEEEEEEECCCCEEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHCC
VSSPCREFQG
CCCCHHHHCC
>Mature Secondary Structure 
PFPQNVPDVTFKTRVRDESVPGSNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNH
CCCCCCCCCEEEEECCCCCCCCCCCEEECCCCHHHHHCCCEEEEEEECCCCCCCCCCCC
LPRYEELHAELVAQGVDQIVCLSVNDAFVMFQWSKHLGTKNIFMLPDGNGEFTRKMGMLV
CCCHHHHHHHHHHCCCCEEEEEEECCEEEEEEEHHHCCCCEEEEEECCCCHHHHHHCCEE
EKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADGDPFEVSDADTMLAYMKGVQSAG
EECCCCCCHHHEEEEEEEECCCCEEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHCC
VSSPCREFQG
CCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]