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The map label for this gene is engD [H]

Identifier: 33863425

GI number: 33863425

Start: 1243758

End: 1244849

Strand: Reverse

Name: engD [H]

Synonym: PMT1155

Alternate gene names: 33863425

Gene position: 1244849-1243758 (Counterclockwise)

Preceding gene: 33863430

Following gene: 33863424

Centisome position: 51.63

GC content: 51.92

Gene sequence:

>1092_bases
ATGCTTAAAGCCGGAATTGTTGGACTACCCAATGTGGGTAAGTCCACGCTTTTCAATGCACTTGTGGCCAACGCGCAGGC
TCAAGCTGCCAATTTTCCCTTCTGCACCATTGAACCGAATGTGGGCAGTGTTGCGGTACCTGATGAGCGCTTGCAGCTGC
TTTGCGATCTAAGTAAGAGCAAGGAGATGATTCCAACGCGCATGGAGTTTGTTGATATCGCTGGTTTGGTCAAGGGGGCT
AGTGAGGGAGAGGGGTTGGGCAACAAATTTCTTGCCAATATTCGCGAGGTTGACGCCATCGTGCATGTGGTGCGTTGCTT
TGAAGACGAGGATGTGATCCATGTCTCTGGATCAGTGGATCCTTCTAGGGATGCTGAGGTCATCAACCTTGAACTCGGCT
TTGCAGATCTCAGTCAGATCGAGAAACGGCGCTTGCGCTTGAAAAAACAGACGCGCACAAGCAATGACGCCCAGTTCGAA
GATGCTGCGCTTGAGCGGATTCAATCTGTGCTTGAGCAAGGTGGTGCTGCTCGTGCTGTAGAGCTCAGTGATGAAGAAGC
GAAAATCATTAAACCGCTTGGCCTACTAACGGCTAAGCCAATTATTTACGCCACCAATGTGAGCGAAGACGATCTTGCCG
GCGGCAATGCCTACTGTGAGGAGGTGACGACCTTGGCGACGCGTGAGGGTGCTGAATGCGTGCGCATTTCAGCTCAGGTG
GAAGCTGAGTTAATTGAACTCGGCGAAGCAGAGCGTATTGATTACCTAGAAGGCCTCGGAGTGAGTGAGGGGGGGCTGAA
GAGTTTGATCAAGGCGACCTATCGGCTTCTAGGTCTTCGTACTTACTTCACCACTGGGGAGAAGGAAACCCGTGCTTGGA
CGTTTAAGGCCGGCATGACAGCGCCGCAGACAGCTGGTGTGATCCATACTGACTTCGAGCGTGGTTTCATACGTGCTCAA
ACCATTGCTTACCAGAAGTTGCTTGAGGCCGGTTCCTTTGCTGAAGCACGCAACAAGGGTTGGCTGCGTAGTGAGGGTAA
GGACTACGTCGTAGAGGAGGGTGATGTTATGGAGTTTCTCTTTAACGTCTAG

Upstream 100 bases:

>100_bases
AGGCACCGTAGCGTAACTCTTTAGTGCTGTTAGCGTTTCTCTGCAGTGCCATATCGCTGTTGCAATGGTTTCTGGCATGG
GCACGGCTAGATTTGCCCCC

Downstream 100 bases:

>100_bases
TTTTTATTCTTCTGGGGCATACTTTCTATTCGACCAAAAAAAGCAAACCAAAACATAGCCCTGAAGGTAAGCAAAACTCT
TGGTTTGTTGATTGATCAAG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPDERLQLLCDLSKSKEMIPTRMEFVDIAGLVKGA
SEGEGLGNKFLANIREVDAIVHVVRCFEDEDVIHVSGSVDPSRDAEVINLELGFADLSQIEKRRLRLKKQTRTSNDAQFE
DAALERIQSVLEQGGAARAVELSDEEAKIIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTTLATREGAECVRISAQV
EAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEKETRAWTFKAGMTAPQTAGVIHTDFERGFIRAQ
TIAYQKLLEAGSFAEARNKGWLRSEGKDYVVEEGDVMEFLFNV

Sequences:

>Translated_363_residues
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPDERLQLLCDLSKSKEMIPTRMEFVDIAGLVKGA
SEGEGLGNKFLANIREVDAIVHVVRCFEDEDVIHVSGSVDPSRDAEVINLELGFADLSQIEKRRLRLKKQTRTSNDAQFE
DAALERIQSVLEQGGAARAVELSDEEAKIIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTTLATREGAECVRISAQV
EAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEKETRAWTFKAGMTAPQTAGVIHTDFERGFIRAQ
TIAYQKLLEAGSFAEARNKGWLRSEGKDYVVEEGDVMEFLFNV
>Mature_363_residues
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPDERLQLLCDLSKSKEMIPTRMEFVDIAGLVKGA
SEGEGLGNKFLANIREVDAIVHVVRCFEDEDVIHVSGSVDPSRDAEVINLELGFADLSQIEKRRLRLKKQTRTSNDAQFE
DAALERIQSVLEQGGAARAVELSDEEAKIIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTTLATREGAECVRISAQV
EAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEKETRAWTFKAGMTAPQTAGVIHTDFERGFIRAQ
TIAYQKLLEAGSFAEARNKGWLRSEGKDYVVEEGDVMEFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=42.9347826086957, Blast_Score=288, Evalue=8e-78,
Organism=Homo sapiens, GI58761502, Length=197, Percent_Identity=36.5482233502538, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=54.5454545454545, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=32.03125, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=42.3497267759563, Blast_Score=285, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=38.3152173913043, Blast_Score=235, Evalue=7e-63,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=34.3915343915344, Blast_Score=203, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6321649, Length=230, Percent_Identity=33.0434782608696, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=40.5994550408719, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=40.5994550408719, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=40.5994550408719, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=37.5384615384615, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24585318, Length=142, Percent_Identity=33.0985915492958, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39581; Mature: 39581

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPDERLQLLCDLSKS
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCEEEECCCCCCEECCHHHHHHHHHHHCC
KEMIPTRMEFVDIAGLVKGASEGEGLGNKFLANIREVDAIVHVVRCFEDEDVIHVSGSVD
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PSRDAEVINLELGFADLSQIEKRRLRLKKQTRTSNDAQFEDAALERIQSVLEQGGAARAV
CCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
ELSDEEAKIIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTTLATREGAECVRISAQV
ECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEHHHH
EAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEKETRAWTFKAGMT
HHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECCCC
APQTAGVIHTDFERGFIRAQTIAYQKLLEAGSFAEARNKGWLRSEGKDYVVEEGDVMEFL
CCCCCCCEEECHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEECCCHHHHHH
FNV
HCC
>Mature Secondary Structure
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPDERLQLLCDLSKS
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCEEEECCCCCCEECCHHHHHHHHHHHCC
KEMIPTRMEFVDIAGLVKGASEGEGLGNKFLANIREVDAIVHVVRCFEDEDVIHVSGSVD
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PSRDAEVINLELGFADLSQIEKRRLRLKKQTRTSNDAQFEDAALERIQSVLEQGGAARAV
CCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
ELSDEEAKIIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTTLATREGAECVRISAQV
ECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEHHHH
EAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEKETRAWTFKAGMT
HHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECCCC
APQTAGVIHTDFERGFIRAQTIAYQKLLEAGSFAEARNKGWLRSEGKDYVVEEGDVMEFL
CCCCCCCEEECHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEECCCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]