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The map label for this gene is recD [H]

Identifier: 33863356

GI number: 33863356

Start: 1171414

End: 1173144

Strand: Reverse

Name: recD [H]

Synonym: PMT1085

Alternate gene names: 33863356

Gene position: 1173144-1171414 (Counterclockwise)

Preceding gene: 33863357

Following gene: 33863355

Centisome position: 48.66

GC content: 53.38

Gene sequence:

>1731_bases
ATGACTCGCAGCGATTCATCCACTTGGCCATCAGGTTTTCCCAGAGCACTGCATCAAACGTTGTTGAGGCGTCTCCCGCC
CAAGGCTTCATCAATTCATCTCGAGGACTTGGTCAACGCCTTGATGGATGCATTAGCCCGCGGTGAGCTGCAGCTGAATC
TCACTGCAATGTCTCCCCCTCAAGAACTCAAAGCAATGGGATGGCCTGAGGCTCATTGTCAGGCCCTGCTGGCTAGTGGC
TGGCTGGAAGGCGCGGCGTCTCCGATGGTTTTAAACGGCAATCAATTGAGTTGGCGTCGTTGGCATGGTGACATGGACGC
TGTGATCAAGGAGTTGATCAACAGGTCAAATGTTGTTCAACCGACTTCAATCTGCACCACACCATCCCATCATCCTGCTT
TGTTGGATGAACTTAACCCTGAACAGCAGGCTGCCGTAGAAGCCATCGATAACCATGGCGTGTTGTTGTTGAGTGGCGGT
CCGGGTACGGGCAAAACCAGCACCATCGTGCAAATGTTGGCGCGGGCAGTCACGTTGAGACCAGGCCTGAAGATTGGTCT
TGCTGCTCCCACAGGCAAAGCAGCAAGACGCCTAGAGGAGGCTGTTCGCAAGGGGCTTGAGACAATCCCTCCCCCCCAGC
GGCAGGCATTGACCAGCCTGCCTTGTAGCACCCTTCACCGTTGGCTTCAGGCCAGGCCTGGTGGGTTTGGTAGGCATCAA
CAACACCCCCTAATGCTTGATCTCCTCGTTATTGATGAGATGTCGATGGTGGAGCTTGCCCTGATGCAGGCGTTATTAAA
CGCTCTTCCTGTTGATAGTCAGCTTGTAATGATTGGTGATCCCGATCAGTTGCCTCCAGTTGGTAGTGGAGCGGTTTGGC
ATCAACTCCAACAGGCTGATATCCGCCAACAGTTCAATCATGGTGCCATTCACCTGCATCAGCTCTATCGCAACCGCGGT
TCACTAGCAACGTTGAGCAGAGTTCTGTGTGATCAGGGCCTGTCTGCTTTTTGGCAACAACTTTCTCTTCTGTCGAAATC
AGCGAACGTTGAGCAGCATCAATACAACCTCAGCAGTATGCCAAGGTTTTTAGTTCAGCACTTGCAGGAGCACAGCAGAA
CACTGCAACGACTCACTGCCGAACTGATGCTCGAGCTGCCAGATGATGCTTATACCTCAACCATGATCAATACCAATTTT
GCTGTTGCAGCTGAGTCTTTGCTGGATTCTCTCGAGCGGTTGATGGTGCTTTGTCCGAAACGTCGTGGTTTTTGGGGAGT
CGATCATGTGCATCGCGCATTGTTGGGTCAAAGCCTTGAGGCTGGAGTAATGCGCTGGCCGTTGGGAACGCCGGTGATGT
GTTGCGAGAACCAAGCGGAACTGGGGCTAGCAAACGGTGACGTTGGCTTGGTGGTTGGTCAAGGAGACAATCTGCGCATC
CTGTTTCGCGTGATCTCTGAGCAGGGAGGACTGACCACACGCTTCATCCACCCGGCCCGATTGAGCATGGTGGAGCCAGC
TTTGGCTCTTACGGTTCATAAGTCTCAGGGGAGTGAGGCTGACCATGTCATTCTTCTCTGGCCGGAAATCACAGCTGTAT
CGGCTACCAGCACTGATGGTTGTGAGAGCGCTTCTCGCTTCGAGAGGAAACTTCTCTACACTGCTATCACGCGCGCGCGA
AAGCGAGTGGATCTCGTTACTGCAATGCCATCTGCTCGTAGTGACGGCTGA

Upstream 100 bases:

>100_bases
ATGGTCGCTCCCTTACTAAACCAGTGCCTGGCTTGATTGTGGAGCCCGCACCATTGGAGCGGGTTTTGCTTTTGGATCGC
TTGCTCAAGAATGGAGGACA

Downstream 100 bases:

>100_bases
GGCTGACACCGCCATGCTGAACGCAACTGCTCGCAGAGGCATGAGCAAGGCCCCCCAGAGAGTTGAGCGTCCTTGGGGTT
GGTATGAAGATCTGCTCGAA

Product: UvrD/REP helicase

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MTRSDSSTWPSGFPRALHQTLLRRLPPKASSIHLEDLVNALMDALARGELQLNLTAMSPPQELKAMGWPEAHCQALLASG
WLEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQPTSICTTPSHHPALLDELNPEQQAAVEAIDNHGVLLLSGG
PGTGKTSTIVQMLARAVTLRPGLKIGLAAPTGKAARRLEEAVRKGLETIPPPQRQALTSLPCSTLHRWLQARPGGFGRHQ
QHPLMLDLLVIDEMSMVELALMQALLNALPVDSQLVMIGDPDQLPPVGSGAVWHQLQQADIRQQFNHGAIHLHQLYRNRG
SLATLSRVLCDQGLSAFWQQLSLLSKSANVEQHQYNLSSMPRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMINTNF
AVAAESLLDSLERLMVLCPKRRGFWGVDHVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRI
LFRVISEQGGLTTRFIHPARLSMVEPALALTVHKSQGSEADHVILLWPEITAVSATSTDGCESASRFERKLLYTAITRAR
KRVDLVTAMPSARSDG

Sequences:

>Translated_576_residues
MTRSDSSTWPSGFPRALHQTLLRRLPPKASSIHLEDLVNALMDALARGELQLNLTAMSPPQELKAMGWPEAHCQALLASG
WLEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQPTSICTTPSHHPALLDELNPEQQAAVEAIDNHGVLLLSGG
PGTGKTSTIVQMLARAVTLRPGLKIGLAAPTGKAARRLEEAVRKGLETIPPPQRQALTSLPCSTLHRWLQARPGGFGRHQ
QHPLMLDLLVIDEMSMVELALMQALLNALPVDSQLVMIGDPDQLPPVGSGAVWHQLQQADIRQQFNHGAIHLHQLYRNRG
SLATLSRVLCDQGLSAFWQQLSLLSKSANVEQHQYNLSSMPRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMINTNF
AVAAESLLDSLERLMVLCPKRRGFWGVDHVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRI
LFRVISEQGGLTTRFIHPARLSMVEPALALTVHKSQGSEADHVILLWPEITAVSATSTDGCESASRFERKLLYTAITRAR
KRVDLVTAMPSARSDG
>Mature_575_residues
TRSDSSTWPSGFPRALHQTLLRRLPPKASSIHLEDLVNALMDALARGELQLNLTAMSPPQELKAMGWPEAHCQALLASGW
LEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQPTSICTTPSHHPALLDELNPEQQAAVEAIDNHGVLLLSGGP
GTGKTSTIVQMLARAVTLRPGLKIGLAAPTGKAARRLEEAVRKGLETIPPPQRQALTSLPCSTLHRWLQARPGGFGRHQQ
HPLMLDLLVIDEMSMVELALMQALLNALPVDSQLVMIGDPDQLPPVGSGAVWHQLQQADIRQQFNHGAIHLHQLYRNRGS
LATLSRVLCDQGLSAFWQQLSLLSKSANVEQHQYNLSSMPRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMINTNFA
VAAESLLDSLERLMVLCPKRRGFWGVDHVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRIL
FRVISEQGGLTTRFIHPARLSMVEPALALTVHKSQGSEADHVILLWPEITAVSATSTDGCESASRFERKLLYTAITRARK
RVDLVTAMPSARSDG

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=519, Percent_Identity=31.4065510597302, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 63184; Mature: 63052

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSDSSTWPSGFPRALHQTLLRRLPPKASSIHLEDLVNALMDALARGELQLNLTAMSPP
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEEECCCH
QELKAMGWPEAHCQALLASGWLEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQ
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHCCCHHHHHHHHHCCCCCCC
PTSICTTPSHHPALLDELNPEQQAAVEAIDNHGVLLLSGGPGTGKTSTIVQMLARAVTLR
CCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCC
PGLKIGLAAPTGKAARRLEEAVRKGLETIPPPQRQALTSLPCSTLHRWLQARPGGFGRHQ
CCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCC
QHPLMLDLLVIDEMSMVELALMQALLNALPVDSQLVMIGDPDQLPPVGSGAVWHQLQQAD
CCCCEEEHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
IRQQFNHGAIHLHQLYRNRGSLATLSRVLCDQGLSAFWQQLSLLSKSANVEQHQYNLSSM
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHH
PRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMINTNFAVAAESLLDSLERLMVLCPK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
RRGFWGVDHVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRI
CCCCCCHHHHHHHHHCCCHHCCCEECCCCCCEEEECCCCCCEECCCCEEEEEECCCCCEE
LFRVISEQGGLTTRFIHPARLSMVEPALALTVHKSQGSEADHVILLWPEITAVSATSTDG
HHHHHHCCCCCEEEEECHHHHHHHCCHHEEEEECCCCCCCCEEEEEECCCEEEECCCCCC
CESASRFERKLLYTAITRARKRVDLVTAMPSARSDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRSDSSTWPSGFPRALHQTLLRRLPPKASSIHLEDLVNALMDALARGELQLNLTAMSPP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEEECCCH
QELKAMGWPEAHCQALLASGWLEGAASPMVLNGNQLSWRRWHGDMDAVIKELINRSNVVQ
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHCCCHHHHHHHHHCCCCCCC
PTSICTTPSHHPALLDELNPEQQAAVEAIDNHGVLLLSGGPGTGKTSTIVQMLARAVTLR
CCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCC
PGLKIGLAAPTGKAARRLEEAVRKGLETIPPPQRQALTSLPCSTLHRWLQARPGGFGRHQ
CCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCC
QHPLMLDLLVIDEMSMVELALMQALLNALPVDSQLVMIGDPDQLPPVGSGAVWHQLQQAD
CCCCEEEHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
IRQQFNHGAIHLHQLYRNRGSLATLSRVLCDQGLSAFWQQLSLLSKSANVEQHQYNLSSM
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHH
PRFLVQHLQEHSRTLQRLTAELMLELPDDAYTSTMINTNFAVAAESLLDSLERLMVLCPK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
RRGFWGVDHVHRALLGQSLEAGVMRWPLGTPVMCCENQAELGLANGDVGLVVGQGDNLRI
CCCCCCHHHHHHHHHCCCHHCCCEECCCCCCEEEECCCCCCEECCCCEEEEEECCCCCEE
LFRVISEQGGLTTRFIHPARLSMVEPALALTVHKSQGSEADHVILLWPEITAVSATSTDG
HHHHHHCCCCCEEEEECHHHHHHHCCHHEEEEECCCCCCCCEEEEEECCCEEEECCCCCC
CESASRFERKLLYTAITRARKRVDLVTAMPSARSDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]