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The map label for this gene is aspC [H]

Identifier: 33863051

GI number: 33863051

Start: 853900

End: 855078

Strand: Direct

Name: aspC [H]

Synonym: PMT0779

Alternate gene names: 33863051

Gene position: 853900-855078 (Clockwise)

Preceding gene: 33863047

Following gene: 33863052

Centisome position: 35.42

GC content: 52.67

Gene sequence:

>1179_bases
ATGCCACTCCCGCCTCATCTTTCCGACCGAGTCGTTGCCCTTCAGCCCTCACTCACACTGGCAATCAGTGCTCGAGCAAA
GGCCCTTCAGCAAGAAGGCCGCGACATCTGCAGCCTGAGTGCTGGTGAGCCAGATTTCAATACCCCTGAATTCATCATTG
ATGCCACGGTGAAGGCACTCCGTGATGGCATCACCCGTTATGGCCCTGCCGCCGGAGATCCCGAACTCCGTGAGGCAATA
GCAACCAAGCTCAGCAAAGAAAACACTGTGCCAACCAATGCAGAGCAAGTGTTGGTGACAAATGGAGGCAAGCAAGCAAT
CTTTAACTTGTTTCAGGTGATCCTCAATCCGGGCGATGAGGTTTTAATCCCTGCTCCTTATTGGCTGAGTTATCCAGAAA
TGGCCCGCTTAGCTGGTGCAAAGGTGACAACACTTCCCTCCACTCCAGAAAACGGTTTCTGCCTAGATCTCAACAACCTA
GAAGCCTCCATCGGCCCTAAAACCCGTCTTTTATTACTTAATTCCCCTGGCAACCCAACCGGCCGTGTGATGGCACGCAA
GGAGCTGGAAACATTGGCTGATCTGCTGAGAGATCATCCCCAGATCCTGGTCATGAGTGATGAGATCTACGAGTTCATTC
TTGAAGAAGGGCAACAGCATTACAGCTTCTCGGCCATAGCACCAGATCTTTCAAACAGAACCTTCATCGTTAACGGCTTT
GCCAAGGGCTGGGCAATGACCGGTTGGCGTTTGGGTTATCTAGCCGGCCCCGCTGATGCTGTAAAAGCTGCTACTGCCCT
CCAAAGCCAGAGCACTAGCAATGTCTGCAGTTTCGCTCAGCGTGGAGCCTTGGCCGCGCTGCAAGGCTCAAGGGAGTGTG
TGAAAAAGATGGTCAAGAGCTACAACACCCGCCGCGAACTCCTCACCTCTGGCTTGCTTAGCCTTGAGGGAATGAGCCTG
GTTCCTCCAAAAGGTGCCTTTTACGCCTTCCCAAAACTGCCACCTGAAAGCCTCGACTCAGTAAGTTTCTGTGAGCAAGC
TCTTGAAAACCATGGGCTTGCGATGGTTCCAGGTGCAGCATTTGGAGACGACAGTTGCGTACGCCTCACCTGTGCGGTTT
CACCAGAAACGATTTGCGATGGACTAGAACGTCTCCGCAAAGCTCTCAAACAGAGCTGA

Upstream 100 bases:

>100_bases
ATGAGCATTAAAAAGCCAATCGAAAGATGTTGGTTGTCCATGTCAGAGCATCAGGCAAGATATGGTCCTTACGGGCATCC
CGCAAGGGGATGCGGCACCA

Downstream 100 bases:

>100_bases
ACAACAAACGCAACAAAGACAACATGCCTTCAAGACCAGGCGGGGCGTTGGTCCGCACTGCATTGATCTGCTTGATTGGG
TTGCTGAGCTGCACCAATCA

Product: aminotransferase class-I

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MPLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSLSAGEPDFNTPEFIIDATVKALRDGITRYGPAAGDPELREAI
ATKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDEVLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNL
EASIGPKTRLLLLNSPGNPTGRVMARKELETLADLLRDHPQILVMSDEIYEFILEEGQQHYSFSAIAPDLSNRTFIVNGF
AKGWAMTGWRLGYLAGPADAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVKSYNTRRELLTSGLLSLEGMSL
VPPKGAFYAFPKLPPESLDSVSFCEQALENHGLAMVPGAAFGDDSCVRLTCAVSPETICDGLERLRKALKQS

Sequences:

>Translated_392_residues
MPLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSLSAGEPDFNTPEFIIDATVKALRDGITRYGPAAGDPELREAI
ATKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDEVLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNL
EASIGPKTRLLLLNSPGNPTGRVMARKELETLADLLRDHPQILVMSDEIYEFILEEGQQHYSFSAIAPDLSNRTFIVNGF
AKGWAMTGWRLGYLAGPADAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVKSYNTRRELLTSGLLSLEGMSL
VPPKGAFYAFPKLPPESLDSVSFCEQALENHGLAMVPGAAFGDDSCVRLTCAVSPETICDGLERLRKALKQS
>Mature_391_residues
PLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSLSAGEPDFNTPEFIIDATVKALRDGITRYGPAAGDPELREAIA
TKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDEVLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNLE
ASIGPKTRLLLLNSPGNPTGRVMARKELETLADLLRDHPQILVMSDEIYEFILEEGQQHYSFSAIAPDLSNRTFIVNGFA
KGWAMTGWRLGYLAGPADAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVKSYNTRRELLTSGLLSLEGMSLV
PPKGAFYAFPKLPPESLDSVSFCEQALENHGLAMVPGAAFGDDSCVRLTCAVSPETICDGLERLRKALKQS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=27.6381909547739, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=27.6381909547739, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI56713254, Length=392, Percent_Identity=28.0612244897959, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI56713256, Length=392, Percent_Identity=28.0612244897959, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=25, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI169881281, Length=306, Percent_Identity=26.1437908496732, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI149944424, Length=236, Percent_Identity=28.3898305084746, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4885351, Length=384, Percent_Identity=22.65625, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI215599424, Length=379, Percent_Identity=23.2189973614776, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI19263340, Length=379, Percent_Identity=23.2189973614776, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI187936925, Length=357, Percent_Identity=24.6498599439776, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14211921, Length=357, Percent_Identity=24.6498599439776, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI7705897, Length=416, Percent_Identity=23.7980769230769, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI33469970, Length=416, Percent_Identity=23.7980769230769, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=29.8941798941799, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=28.9405684754522, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1788627, Length=353, Percent_Identity=28.0453257790368, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790797, Length=368, Percent_Identity=24.7282608695652, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787909, Length=375, Percent_Identity=24, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=26.4864864864865, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=406, Percent_Identity=26.6009852216749, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=406, Percent_Identity=26.6009852216749, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=400, Percent_Identity=24.25, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=362, Percent_Identity=22.6519337016575, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=320, Percent_Identity=29.0625, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=340, Percent_Identity=23.2352941176471, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573069, Length=354, Percent_Identity=24.5762711864407, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646114, Length=354, Percent_Identity=24.5762711864407, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573067, Length=354, Percent_Identity=24.5762711864407, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573065, Length=354, Percent_Identity=24.5762711864407, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI45551451, Length=341, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641770, Length=341, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641760, Length=341, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641768, Length=341, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641766, Length=341, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641764, Length=341, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18859735, Length=366, Percent_Identity=23.4972677595628, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42274; Mature: 42143

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSLSAGEPDFNTPEFIIDATVKAL
CCCCCCCCCCEEEECCCEEEEEHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHH
RDGITRYGPAAGDPELREAIATKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDE
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
VLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNLEASIGPKTRLLLLNSPGNPT
EEECCCHHCCCHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCH
GRVMARKELETLADLLRDHPQILVMSDEIYEFILEEGQQHYSFSAIAPDLSNRTFIVNGF
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCHHHEEEHEECCCCCCCEEEEECC
AKGWAMTGWRLGYLAGPADAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVKS
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHH
YNTRRELLTSGLLSLEGMSLVPPKGAFYAFPKLPPESLDSVSFCEQALENHGLAMVPGAA
HHHHHHHHHHHHHHCCCCEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCEEEECCCC
FGDDSCVRLTCAVSPETICDGLERLRKALKQS
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSLSAGEPDFNTPEFIIDATVKAL
CCCCCCCCCEEEECCCEEEEEHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHH
RDGITRYGPAAGDPELREAIATKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDE
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
VLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNLEASIGPKTRLLLLNSPGNPT
EEECCCHHCCCHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCH
GRVMARKELETLADLLRDHPQILVMSDEIYEFILEEGQQHYSFSAIAPDLSNRTFIVNGF
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCHHHEEEHEECCCCCCCEEEEECC
AKGWAMTGWRLGYLAGPADAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVKS
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHH
YNTRRELLTSGLLSLEGMSLVPPKGAFYAFPKLPPESLDSVSFCEQALENHGLAMVPGAA
HHHHHHHHHHHHHHCCCCEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCEEEECCCC
FGDDSCVRLTCAVSPETICDGLERLRKALKQS
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]