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The map label for this gene is macB [H]

Identifier: 33862950

GI number: 33862950

Start: 734292

End: 735521

Strand: Reverse

Name: macB [H]

Synonym: PMT0678

Alternate gene names: 33862950

Gene position: 735521-734292 (Counterclockwise)

Preceding gene: 33862951

Following gene: 33862949

Centisome position: 30.51

GC content: 50.24

Gene sequence:

>1230_bases
ATGAATAGCTCACTTCCGCTCATCGAAACGGTGAGCATGGCGTTCTCAACCCTTAAAGCCAATCGCCTACGTAGTCTCCT
GACAATGCTCGGCATTGTGATCGGCAATGCTTCTGTCATCACCCTGGTAGGGGTTGGCAGGGGGGCTCAGAATCTGGCTG
AGGCTCAACTAAGCAACCTGGGCGCCAATGTGTTGTTTGTGGTGCCTGGCAACAACGACACTCGTCGTCGCGGTGTGGCC
TTCCCGCGAAATCTCGTCATCGAAGATTCAGATGCAATCGCTGAGCAAGTTCCAAGCGTGAAAGAAGTCGCACCACAGAT
CAGCTCAAGCGAGGTGATTCAAGCGGGTGCCCAAAGTGCTACGAGTTCAATCTCTGGGGTGACCCCATCGTTTCTACCAG
TGCGCAACTTCGAAGTAGCCCGTGGAAGATTTATTAGTGATCTAGATCTTCGTAGCGCACGCAATGTGGTTGTGATTGGT
CCCGACCTTGTCAATAAACTCTTTCCAACGAGTGCTGCAGTCGGTAAGATTCTACGAATTAAGGATCAATCATTTGAAGT
AATCGGTGTAATGGCTCCTAAAGGAGCAGTGTTTGGAAACAATCAAGATGAAAACGCGTACATTCCACTCACAACAATGG
TTAGCCGGATCACAGGCAGAGATCCAACCTATGGCGTCAGCCTTAGTTTTATCAGTGTGGAAGCCAAGAATGAAGAAAGC
ACGGGGGCAGCAAAATTCCAGATCACCAACCTGCTCCGTCAACGACATCGAATCCTGAGAGATGACGACTTTGCAGTTCG
ATCACAGAAAGATGCCCTCAGCATCGTCAACACAATCACCGGAGGACTAACCCTCATGTTGGCAGCAATCGGAGGGATAT
CGCTGCTAGTAGGAGGAATCGGAATCATGAATATCATGCTGGTTGCGGTCAGTGAACGCACTGAGGAAATCGGACTAAGA
AAGGCCCTAGGAGCTCGAAATAGCGATGTATTGAGCCAATTCCTAATCGAGTCACTCGTTCTTGCAAGCTTTGGTGGCGT
CATTGGCACAGCTGTAGGTGTTGGTGCCGTCACAACAATCGGAGTTTTGACCCCTCTCCCGGCAGCAATCGGAATAAGCG
TCGTTCTAATCACCGTTAGTCTCTCTGGATCAATTGGTTTGATCTTTGGTGTTTTGCCCGCCAGACGTGCAGCAAGACTT
GACCCAATCGTTGCCCTCCGGCGCCTGTAA

Upstream 100 bases:

>100_bases
TGAAGGAGAGGTGGTAACAATGCAGCTCAGTAATGGCAAAGTTCATCGCGGCACAGGCGGCAAGCTGCCAATGAAGCTCG
ACTCAATGGACTGAGGGCTC

Downstream 100 bases:

>100_bases
AACCTTTTTGATTTTCAGAGAATAGGCAAATCAAAAAAGGGGTAGCAATCACAACTCCCCCGCTACGAAAACAATGAGGT
CAAGCGCCCAACGCAAGCAA

Product: ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNSSLPLIETVSMAFSTLKANRLRSLLTMLGIVIGNASVITLVGVGRGAQNLAEAQLSNLGANVLFVVPGNNDTRRRGVA
FPRNLVIEDSDAIAEQVPSVKEVAPQISSSEVIQAGAQSATSSISGVTPSFLPVRNFEVARGRFISDLDLRSARNVVVIG
PDLVNKLFPTSAAVGKILRIKDQSFEVIGVMAPKGAVFGNNQDENAYIPLTTMVSRITGRDPTYGVSLSFISVEAKNEES
TGAAKFQITNLLRQRHRILRDDDFAVRSQKDALSIVNTITGGLTLMLAAIGGISLLVGGIGIMNIMLVAVSERTEEIGLR
KALGARNSDVLSQFLIESLVLASFGGVIGTAVGVGAVTTIGVLTPLPAAIGISVVLITVSLSGSIGLIFGVLPARRAARL
DPIVALRRL

Sequences:

>Translated_409_residues
MNSSLPLIETVSMAFSTLKANRLRSLLTMLGIVIGNASVITLVGVGRGAQNLAEAQLSNLGANVLFVVPGNNDTRRRGVA
FPRNLVIEDSDAIAEQVPSVKEVAPQISSSEVIQAGAQSATSSISGVTPSFLPVRNFEVARGRFISDLDLRSARNVVVIG
PDLVNKLFPTSAAVGKILRIKDQSFEVIGVMAPKGAVFGNNQDENAYIPLTTMVSRITGRDPTYGVSLSFISVEAKNEES
TGAAKFQITNLLRQRHRILRDDDFAVRSQKDALSIVNTITGGLTLMLAAIGGISLLVGGIGIMNIMLVAVSERTEEIGLR
KALGARNSDVLSQFLIESLVLASFGGVIGTAVGVGAVTTIGVLTPLPAAIGISVVLITVSLSGSIGLIFGVLPARRAARL
DPIVALRRL
>Mature_409_residues
MNSSLPLIETVSMAFSTLKANRLRSLLTMLGIVIGNASVITLVGVGRGAQNLAEAQLSNLGANVLFVVPGNNDTRRRGVA
FPRNLVIEDSDAIAEQVPSVKEVAPQISSSEVIQAGAQSATSSISGVTPSFLPVRNFEVARGRFISDLDLRSARNVVVIG
PDLVNKLFPTSAAVGKILRIKDQSFEVIGVMAPKGAVFGNNQDENAYIPLTTMVSRITGRDPTYGVSLSFISVEAKNEES
TGAAKFQITNLLRQRHRILRDDDFAVRSQKDALSIVNTITGGLTLMLAAIGGISLLVGGIGIMNIMLVAVSERTEEIGLR
KALGARNSDVLSQFLIESLVLASFGGVIGTAVGVGAVTTIGVLTPLPAAIGISVVLITVSLSGSIGLIFGVLPARRAARL
DPIVALRRL

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=403, Percent_Identity=36.2282878411911, Blast_Score=205, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42946; Mature: 42946

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSLPLIETVSMAFSTLKANRLRSLLTMLGIVIGNASVITLVGVGRGAQNLAEAQLSNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHC
GANVLFVVPGNNDTRRRGVAFPRNLVIEDSDAIAEQVPSVKEVAPQISSSEVIQAGAQSA
CCCEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHH
TSSISGVTPSFLPVRNFEVARGRFISDLDLRSARNVVVIGPDLVNKLFPTSAAVGKILRI
HHHCCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCCEEEECHHHHHHHCCCHHHHHHEEEE
KDQSFEVIGVMAPKGAVFGNNQDENAYIPLTTMVSRITGRDPTYGVSLSFISVEAKNEES
CCCCEEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEEEEEEEEECCCCC
TGAAKFQITNLLRQRHRILRDDDFAVRSQKDALSIVNTITGGLTLMLAAIGGISLLVGGI
CCCHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIMNIMLVAVSERTEEIGLRKALGARNSDVLSQFLIESLVLASFGGVIGTAVGVGAVTTI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLTPLPAAIGISVVLITVSLSGSIGLIFGVLPARRAARLDPIVALRRL
HHHHCCCHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure
MNSSLPLIETVSMAFSTLKANRLRSLLTMLGIVIGNASVITLVGVGRGAQNLAEAQLSNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHC
GANVLFVVPGNNDTRRRGVAFPRNLVIEDSDAIAEQVPSVKEVAPQISSSEVIQAGAQSA
CCCEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHH
TSSISGVTPSFLPVRNFEVARGRFISDLDLRSARNVVVIGPDLVNKLFPTSAAVGKILRI
HHHCCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCCEEEECHHHHHHHCCCHHHHHHEEEE
KDQSFEVIGVMAPKGAVFGNNQDENAYIPLTTMVSRITGRDPTYGVSLSFISVEAKNEES
CCCCEEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEEEEEEEEECCCCC
TGAAKFQITNLLRQRHRILRDDDFAVRSQKDALSIVNTITGGLTLMLAAIGGISLLVGGI
CCCHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIMNIMLVAVSERTEEIGLRKALGARNSDVLSQFLIESLVLASFGGVIGTAVGVGAVTTI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLTPLPAAIGISVVLITVSLSGSIGLIFGVLPARRAARLDPIVALRRL
HHHHCCCHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA