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The map label for this gene is pqqL [C]

Identifier: 33862864

GI number: 33862864

Start: 647772

End: 648980

Strand: Direct

Name: pqqL [C]

Synonym: PMT0591

Alternate gene names: 33862864

Gene position: 647772-648980 (Clockwise)

Preceding gene: 33862852

Following gene: 33862865

Centisome position: 26.87

GC content: 52.44

Gene sequence:

>1209_bases
GTGTTGGCATCCATGCCAGATGCACCACTGACTTGTTTAGACCTCTGGTGCAAAGCAGGTAGTTCAAGCGAACAAAAAGG
AGAGGAAGGACTAGCCCACTTTCTTGAACACATGGTGTTCAAGGGAAGCTCACAGATGGAGGCGGGAGAATTCGATCGCA
AAATCGAAGCGCTTGGAGGCAGCAGCAATGCCGCCACAGGTTTCGATGACGTCCACTTTCACGTTCTTGTACCACCAACG
GCAGCTAGGGCAGCACTTGATCTACTGCTCAACCTCGTTCTGACTCCAGCTCTGCGTTCAGAGGCCTATGCCATGGAGCG
AGACGTCGTATTGGAGGAAATTGCCCAATATCGAGATCAACCGGATGATCAAGTCCTCCAACAGCTTCTCGAAGCATGCT
GCGAAGATCATCCCTACGGCCGAGCCATCCTTGGCTGTGAAGCAAGCCTAAAAACAAGTACTCCCGAGCAAATGAGGGAG
TTCCACAGCCGCCGCTATCGAGGCCCGAATTGTTGCCTAGCAATTGCGGGTGCCATTCCGATAGGCCTGGAAGAAATCTT
GAACAACAGCCGTCTGGCTGAGTTGAATCACCAAACGATGGAGGACATTGATCCTGCCATTTCTCCAACGCTCAGCTTTC
AAAAAGGGCGACGAGAAATTCAAGTCCCCAGGCTGGAATCCACCCGGCTATTGATGACCTGGCCGATGCCCCCTGCCTCA
AACCAAGAGATGGTGATGGGAGCTGACCTGGCGACCACCCTGCTTGCGGAAGGACGTCGCAGTCGACTGGTGCATCACCT
CAGAGAGGAAATGCAAATCGTGGAATCGATCGATATGGATGTAACCGTGTTGGAACAAGGCAGCCTTGTATTGCTAGAAG
CATGCTGCAACGAGACGCAGCTGGACAGGGTGGAAAAGGAAATCCACCATTTACTGCAGACGAGCCTCGAATCAACACCC
AAGAATCAGGAGATCGAACGAGCTAGCCAACTGGTTTCAAATGGACTGTGTTTCAGCCTTGAAGCTCCCAGTCAAGTAGC
CGGCCTGGCAGGGAATCAAGCTCTTTGGAATCGTCCTCAATCCTTGTTGGCACCACTTGATCACCTGTCTGCATGGACGC
CGACTCGACTTCTCGAGCAAATGCTTCCATTACTGCAACCAGAGAGGAGCTTCACCCTTGTTGCCAGACCGATGGAAGCA
GAAGAATGA

Upstream 100 bases:

>100_bases
GGCAAGAAGGATCAGAATGGGACTTTGACATGCACCTCTGACACGCTCCACCCCTAAACCCAGTCTTCAACACTGGGCTC
TAAAGAACAAGACCCGCTGC

Downstream 100 bases:

>100_bases
ATCCTCTCGATGTGGTTTTAGATCCAATCGCCGCACCGGGAGTTATCGCCGCCAAGCTCTGGGTTAGAGGCGGCAGTGGT
GCTGACCCAAAAGGGCAACG

Product: Zn-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MLASMPDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGGSSNAATGFDDVHFHVLVPPT
AARAALDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQPDDQVLQQLLEACCEDHPYGRAILGCEASLKTSTPEQMRE
FHSRRYRGPNCCLAIAGAIPIGLEEILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPAS
NQEMVMGADLATTLLAEGRRSRLVHHLREEMQIVESIDMDVTVLEQGSLVLLEACCNETQLDRVEKEIHHLLQTSLESTP
KNQEIERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQSLLAPLDHLSAWTPTRLLEQMLPLLQPERSFTLVARPMEA
EE

Sequences:

>Translated_402_residues
MLASMPDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGGSSNAATGFDDVHFHVLVPPT
AARAALDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQPDDQVLQQLLEACCEDHPYGRAILGCEASLKTSTPEQMRE
FHSRRYRGPNCCLAIAGAIPIGLEEILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPAS
NQEMVMGADLATTLLAEGRRSRLVHHLREEMQIVESIDMDVTVLEQGSLVLLEACCNETQLDRVEKEIHHLLQTSLESTP
KNQEIERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQSLLAPLDHLSAWTPTRLLEQMLPLLQPERSFTLVARPMEA
EE
>Mature_402_residues
MLASMPDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGGSSNAATGFDDVHFHVLVPPT
AARAALDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQPDDQVLQQLLEACCEDHPYGRAILGCEASLKTSTPEQMRE
FHSRRYRGPNCCLAIAGAIPIGLEEILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPAS
NQEMVMGADLATTLLAEGRRSRLVHHLREEMQIVESIDMDVTVLEQGSLVLLEACCNETQLDRVEKEIHHLLQTSLESTP
KNQEIERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQSLLAPLDHLSAWTPTRLLEQMLPLLQPERSFTLVARPMEA
EE

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=179, Percent_Identity=27.9329608938547, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI46593007, Length=201, Percent_Identity=23.8805970149254, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=167, Percent_Identity=24.5508982035928, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=175, Percent_Identity=29.1428571428571, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21357875, Length=172, Percent_Identity=27.3255813953488, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646943, Length=172, Percent_Identity=27.3255813953488, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667786, Length=239, Percent_Identity=28.8702928870293, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641429, Length=286, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 44647; Mature: 44647

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASMPDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGG
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
SSNAATGFDDVHFHVLVPPTAARAALDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQ
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDDQVLQQLLEACCEDHPYGRAILGCEASLKTSTPEQMREFHSRRYRGPNCCLAIAGAIP
CHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCC
IGLEEILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPAS
CCHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCC
NQEMVMGADLATTLLAEGRRSRLVHHLREEMQIVESIDMDVTVLEQGSLVLLEACCNETQ
CCCEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEHHHCCCHH
LDRVEKEIHHLLQTSLESTPKNQEIERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQ
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHCCCCHHHHCCCH
SLLAPLDHLSAWTPTRLLEQMLPLLQPERSFTLVARPMEAEE
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MLASMPDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGG
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
SSNAATGFDDVHFHVLVPPTAARAALDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQ
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDDQVLQQLLEACCEDHPYGRAILGCEASLKTSTPEQMREFHSRRYRGPNCCLAIAGAIP
CHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCC
IGLEEILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPAS
CCHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCC
NQEMVMGADLATTLLAEGRRSRLVHHLREEMQIVESIDMDVTVLEQGSLVLLEACCNETQ
CCCEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEHHHCCCHH
LDRVEKEIHHLLQTSLESTPKNQEIERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQ
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHCCCCHHHHCCCH
SLLAPLDHLSAWTPTRLLEQMLPLLQPERSFTLVARPMEAEE
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA