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The map label for this gene is cvrA [H]

Identifier: 33862815

GI number: 33862815

Start: 593985

End: 595175

Strand: Direct

Name: cvrA [H]

Synonym: PMT0542

Alternate gene names: 33862815

Gene position: 593985-595175 (Clockwise)

Preceding gene: 33862810

Following gene: 33862817

Centisome position: 24.64

GC content: 52.31

Gene sequence:

>1191_bases
GTGATCTTCGCCTATTGCCTGCTTTCAAGACGATTGTCCAGGACAGCAGTCTCTGGACCACTGGTCTTTGTTGCGCTGGG
CTTAGTTCTTGGCCCTGCCAACCTGGGCTGGCTCAACATCTCATTGGATTCAGCACTGCTAAGGCGTCTGGCAGAGATCA
CATTGGGTCTCGTGTTGTTTACCGATGCAGCAGCATTGGACTGGACAGTGTTACGCAACAGTGCCCGCCTGCCAATGCGT
CTGCTGCTGCTCGGACTGCCACTCAGCATTCTGATGGGTTTCGTGGTGGCCCGATTGATATTGCCTGAACTAAGCCTGAT
TGAAGCAGCCCTACTTGCTGTGGTGCTCGCTCCAACAGATGCGGCACTTGGCGAAGCGGTGACCACCAACCTCGAAGTAC
CAGAAGCTATCCGCGAAGACCTCAATGTTGAAAGTGGCCTCAATGACGGAATTTGTGTTCCTATGTTGTTGTGCTTTCTT
GGTATATCAACTGGTCATCTTGACCAGATCAATGGACCGAAGGATGCATTGCAGAGCTTTGCCCAGCTGCTTTTCAGTGA
AATAGGTCTCGGCCTCGTGATAGGAGCCTTTGTTGGATTATTGGGTAGTTGGTTAAGGGATCAGGCAGAACAACGCAAAT
GGATTGCTGAGGATTGGAGGCCTTTGATCACAGTGGCCCTGGCCCTGAGTGCCTACACCCTCGCCCAAACCCTTCATGGG
AGCGGATTCATTTCCTGTTTCATCGCTGGTCTTTTTTATGGGATCTGCAGTCGCAAAGAACTCAAGGACGGTGAGATGGT
GGCTTCCCTGGCAATGGGGGACATGTTGGCCCTACTGACCTGGGTTTTATTTGGCAGTGCCATGGTGCCCGATGCCTGGA
GCCACATCACAGTCGCAAGTGTGGTCTATGGGGCTTTAAGCCTGACACTAGTGCGCGTTCTTCCCGTTGCCTTAGTAACC
AGCGGCCTTGGACTTGATCACTGGACGAAACTCTTCGTTGGTTGGTTTGGGCCAAGAGGTTTAGCCAGCATTGTGTTTGT
TGTGATGGTGGTAGACGCGGCGCTTCCAAGCGCACAAGCGATTCTTACCACCACAACGGTCACTATTGTTTTGAGTGTGA
TTGCCCATGGCATTACAGCTAACCGGTTTTCGATGTTCTACGGCCGTTGGGAAAGAAGCCATGCAGGCTGA

Upstream 100 bases:

>100_bases
ATTTCGAGATCTACACCCGAATTAAGGGCAGCATCAAGGGGACTCAAACTCACCACTAGCCGTGCTCCACAGCGACCTTG
ACCTGGCAGTGATCAGTTTA

Downstream 100 bases:

>100_bases
AGTAAAGAAGACTGAGTTTATAAAGACTAAACAAAAAAGACGAAAGCCCAAAAGGACAAGCTAGTTAAATGAACGATATA
TTGAAATGAAAGTATCTACA

Product: CPA1 family Na(+)/H(+) antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLFTDAAALDWTVLRNSARLPMR
LLLLGLPLSILMGFVVARLILPELSLIEAALLAVVLAPTDAALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFL
GISTGHLDQINGPKDALQSFAQLLFSEIGLGLVIGAFVGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
SGFISCFIAGLFYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSHITVASVVYGALSLTLVRVLPVALVT
SGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPSAQAILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG

Sequences:

>Translated_396_residues
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLFTDAAALDWTVLRNSARLPMR
LLLLGLPLSILMGFVVARLILPELSLIEAALLAVVLAPTDAALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFL
GISTGHLDQINGPKDALQSFAQLLFSEIGLGLVIGAFVGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
SGFISCFIAGLFYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSHITVASVVYGALSLTLVRVLPVALVT
SGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPSAQAILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG
>Mature_396_residues
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLFTDAAALDWTVLRNSARLPMR
LLLLGLPLSILMGFVVARLILPELSLIEAALLAVVLAPTDAALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFL
GISTGHLDQINGPKDALQSFAQLLFSEIGLGLVIGAFVGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
SGFISCFIAGLFYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSHITVASVVYGALSLTLVRVLPVALVT
SGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPSAQAILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 42394; Mature: 42394

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLF
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
TDAAALDWTVLRNSARLPMRLLLLGLPLSILMGFVVARLILPELSLIEAALLAVVLAPTD
HCHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFLGISTGHLDQINGPKDALQSF
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AQLLFSEIGLGLVIGAFVGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGFISCFIAGLFYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSHITVAS
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VVYGALSLTLVRVLPVALVTSGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPSAQA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHH
ILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIFAYCLLSRRLSRTAVSGPLVFVALGLVLGPANLGWLNISLDSALLRRLAEITLGLVLF
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
TDAAALDWTVLRNSARLPMRLLLLGLPLSILMGFVVARLILPELSLIEAALLAVVLAPTD
HCHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AALGEAVTTNLEVPEAIREDLNVESGLNDGICVPMLLCFLGISTGHLDQINGPKDALQSF
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AQLLFSEIGLGLVIGAFVGLLGSWLRDQAEQRKWIAEDWRPLITVALALSAYTLAQTLHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGFISCFIAGLFYGICSRKELKDGEMVASLAMGDMLALLTWVLFGSAMVPDAWSHITVAS
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VVYGALSLTLVRVLPVALVTSGLGLDHWTKLFVGWFGPRGLASIVFVVMVVDAALPSAQA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHH
ILTTTTVTIVLSVIAHGITANRFSMFYGRWERSHAG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA