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The map label for this gene is btuE [C]

Identifier: 33862398

GI number: 33862398

Start: 141551

End: 142036

Strand: Reverse

Name: btuE [C]

Synonym: PMT0125

Alternate gene names: 33862398

Gene position: 142036-141551 (Counterclockwise)

Preceding gene: 33862401

Following gene: 33862393

Centisome position: 5.89

GC content: 55.35

Gene sequence:

>486_bases
ATGTCCATGGCCATCAACATCAGCCAGATTGTGGTTCGCACTCCAGAGGGTGCTGAGAAGTCCCTCAGCGAATACAGCGG
CACGGTGCTGTTAATCGTGAATGTGGCCAGCCGATGTGGATTTACCAAGCAATACAAAGGCCTGCAGGCGCTGCAAAACA
CATACGGCCCTCAGGGACTAAAGGTGCTGGGCTTTCCTTGCAACGACTTTGGCGCCCAGGAGCCCGGCACCCTCGAGGAG
ATCAAGAGCTTCTGTTCCACCACCTACGGCGCCAGCTTCGAATTGTTTGACAAGGTGCACGCCATGGGCAAAACCACCGA
GCCCTACACCACCCTCAATCAAACTGAACCAGCAGGAGATGTGGCCTGGAACTTCGAAAAGTTTCTTGTGGGTAAGGACG
GCACCGTGCTCAAACGTTTCAAGAGCGGCGTGGAACCTGAAAGCACTGAGCTCAAGGCAGCTATCGACCAAGCCCTGATG
GCCTGA

Upstream 100 bases:

>100_bases
CCGGACTGGTTGCCCCCGTTGCCTCGTTCATCGGCCAACCGTCAAGGCGAGCACACTGTATGGCGAATGGTCCTCGCTAG
GGTCTTGAAGACAAAACCAA

Downstream 100 bases:

>100_bases
ACTGCCAACCAATCAAAAAACCAAGGGCTGCAACACCAAGACCTAAGCCCATGGTTAAACCAATCAATCCCAGCGCTGAC
AACCAAGCCCCCTGAGAGAT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSMAINISQIVVRTPEGAEKSLSEYSGTVLLIVNVASRCGFTKQYKGLQALQNTYGPQGLKVLGFPCNDFGAQEPGTLEE
IKSFCSTTYGASFELFDKVHAMGKTTEPYTTLNQTEPAGDVAWNFEKFLVGKDGTVLKRFKSGVEPESTELKAAIDQALM
A

Sequences:

>Translated_161_residues
MSMAINISQIVVRTPEGAEKSLSEYSGTVLLIVNVASRCGFTKQYKGLQALQNTYGPQGLKVLGFPCNDFGAQEPGTLEE
IKSFCSTTYGASFELFDKVHAMGKTTEPYTTLNQTEPAGDVAWNFEKFLVGKDGTVLKRFKSGVEPESTELKAAIDQALM
A
>Mature_160_residues
SMAINISQIVVRTPEGAEKSLSEYSGTVLLIVNVASRCGFTKQYKGLQALQNTYGPQGLKVLGFPCNDFGAQEPGTLEEI
KSFCSTTYGASFELFDKVHAMGKTTEPYTTLNQTEPAGDVAWNFEKFLVGKDGTVLKRFKSGVEPESTELKAAIDQALMA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=119, Percent_Identity=48.7394957983193, Blast_Score=113, Evalue=6e-26,
Organism=Homo sapiens, GI192455698, Length=152, Percent_Identity=36.1842105263158, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI75709200, Length=154, Percent_Identity=36.3636363636364, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI90903240, Length=150, Percent_Identity=36.6666666666667, Blast_Score=101, Evalue=2e-22,
Organism=Homo sapiens, GI4557629, Length=163, Percent_Identity=37.4233128834356, Blast_Score=94, Evalue=5e-20,
Organism=Homo sapiens, GI41406084, Length=153, Percent_Identity=41.1764705882353, Blast_Score=90, Evalue=7e-19,
Organism=Homo sapiens, GI6006001, Length=143, Percent_Identity=39.1608391608392, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI90903238, Length=132, Percent_Identity=35.6060606060606, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI33186887, Length=138, Percent_Identity=38.4057971014493, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI32967607, Length=175, Percent_Identity=32, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788003, Length=181, Percent_Identity=39.7790055248619, Blast_Score=137, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=40.625, Blast_Score=119, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17506887, Length=155, Percent_Identity=40, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI193210707, Length=153, Percent_Identity=39.8692810457516, Blast_Score=102, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=33.5443037974684, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193209493, Length=179, Percent_Identity=29.608938547486, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17550320, Length=174, Percent_Identity=28.1609195402299, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193210709, Length=71, Percent_Identity=49.2957746478873, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=34.7368421052632, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322228, Length=143, Percent_Identity=43.3566433566434, Blast_Score=124, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319721, Length=153, Percent_Identity=39.2156862745098, Blast_Score=123, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6322826, Length=138, Percent_Identity=39.1304347826087, Blast_Score=104, Evalue=6e-24,
Organism=Drosophila melanogaster, GI85726443, Length=148, Percent_Identity=38.5135135135135, Blast_Score=102, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24656772, Length=149, Percent_Identity=37.5838926174497, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24656777, Length=149, Percent_Identity=37.5838926174497, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24656767, Length=149, Percent_Identity=37.5838926174497, Blast_Score=97, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17473; Mature: 17342

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMAINISQIVVRTPEGAEKSLSEYSGTVLLIVNVASRCGFTKQYKGLQALQNTYGPQGL
CCEEEEHHEEEEECCCCHHHHHHHHCCEEEEEEEEHHHCCCHHHHHHHHHHHHCCCCCCC
KVLGFPCNDFGAQEPGTLEEIKSFCSTTYGASFELFDKVHAMGKTTEPYTTLNQTEPAGD
EEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
VAWNFEKFLVGKDGTVLKRFKSGVEPESTELKAAIDQALMA
EEECHHHEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SMAINISQIVVRTPEGAEKSLSEYSGTVLLIVNVASRCGFTKQYKGLQALQNTYGPQGL
CEEEEHHEEEEECCCCHHHHHHHHCCEEEEEEEEHHHCCCHHHHHHHHHHHHCCCCCCC
KVLGFPCNDFGAQEPGTLEEIKSFCSTTYGASFELFDKVHAMGKTTEPYTTLNQTEPAGD
EEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
VAWNFEKFLVGKDGTVLKRFKSGVEPESTELKAAIDQALMA
EEECHHHEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]