Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 33862392

GI number: 33862392

Start: 136728

End: 137387

Strand: Reverse

Name: infC [H]

Synonym: PMT0119

Alternate gene names: 33862392

Gene position: 137387-136728 (Counterclockwise)

Preceding gene: 33862393

Following gene: 33862391

Centisome position: 5.7

GC content: 51.21

Gene sequence:

>660_bases
ATGCCACCACGTCCTCGTTTTGACCGTCGCGCACCCGTCAGGGAGCTCCCCAACATTAATGACCGCATCAATTATCCCAA
GTTGCGGGTCGTTGACGCAGACGGAACTCAGCTCGGGGTGATCAACAGGGAAGAAGCCCTTGATGTAGCAAAAGATAGGG
AACTCGATCTGGTCCTTGTCAGCGAGAAAGCGGATCCACCCGTTTGCCGAATCATGGATTACGGCAAATTCAAGTTTGAG
CAGGAGAAGAAAGCCAAGGAAGCCAAAAAGAAGTCGCATCAGACCGAAGTCAAAGAAGTAAAAATGCGCTACAAAATCGA
TCAGCACGACTACAACGTGCGCATCGGCCAAGCCGTGCGATTCCTCAAGGCTGGTGACAAAGTCAAATGCACCGTTATCT
TCCGGGGTCGGGAAATTCAGCACACTGCCCTGGCTGAAACGCTGCTACGACGTATGGCAAAAGACCTGGAAGAACAGGCT
GAAATTCAGCAAGCTCCTAAGCGTGAAGGTCGGAACATGATCATGTTCCTTACACCGCGCAAAACACCGCTGATCAAAAC
AGATAAGGAAAACCAAATTCCTACGCGTGCGGTTCGCACCATCACAGCCCCACCTCGAGCCACTGCTGCTGCCAAAACAC
AGCTCAACAAGGATCAATAA

Upstream 100 bases:

>100_bases
GCGAAGCGCTATCACTGATTCAAGCGGGTCTAAGGTGAAGGGTGCAGACATAAAACCTTCTGGTCTCCTTGTCGTCTGCT
CTATTCCCTTATCTCACTGA

Downstream 100 bases:

>100_bases
ATCCCTAACTTCAGAGAAATCAAGCACCTGCTAGCCCTTGAGAGCAACCTGCTGAACCCCTAAGTGTGTTCTGGTCGATC
AATTCAGAAGGGTCGACCCC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLVSEKADPPVCRIMDYGKFKFE
QEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVRFLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQA
EIQQAPKREGRNMIMFLTPRKTPLIKTDKENQIPTRAVRTITAPPRATAAAKTQLNKDQ

Sequences:

>Translated_219_residues
MPPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLVSEKADPPVCRIMDYGKFKFE
QEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVRFLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQA
EIQQAPKREGRNMIMFLTPRKTPLIKTDKENQIPTRAVRTITAPPRATAAAKTQLNKDQ
>Mature_218_residues
PPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLVSEKADPPVCRIMDYGKFKFEQ
EKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVRFLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQAE
IQQAPKREGRNMIMFLTPRKTPLIKTDKENQIPTRAVRTITAPPRATAAAKTQLNKDQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=46.7065868263473, Blast_Score=134, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 25324; Mature: 25193

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLV
CCCCCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHCCCCEEEEEE
SEKADPPVCRIMDYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVR
ECCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHH
FLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQAEIQQAPKREGRNMIMFLTPR
HHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKTDKENQIPTRAVRTITAPPRATAAAKTQLNKDQ
CCCCEECCCCCCCCHHHHEEECCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
PPRPRFDRRAPVRELPNINDRINYPKLRVVDADGTQLGVINREEALDVAKDRELDLVLV
CCCCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHCCCCEEEEEE
SEKADPPVCRIMDYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYNVRIGQAVR
ECCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHH
FLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEQAEIQQAPKREGRNMIMFLTPR
HHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKTDKENQIPTRAVRTITAPPRATAAAKTQLNKDQ
CCCCEECCCCCCCCHHHHEEECCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA