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The map label for this gene is tsr

Identifier: 30065597

GI number: 30065597

Start: 4550098

End: 4551762

Strand: Direct

Name: tsr

Synonym: S4656

Alternate gene names: 30065597

Gene position: 4550098-4551762 (Clockwise)

Preceding gene: 30065596

Following gene: 30065605

Centisome position: 98.93

GC content: 53.99

Gene sequence:

>1665_bases
ATGTTAAAACGTATCAAGATCGTGACCAGCTTACTGCTGGTTTTGGCCGTTTTTGGCCTTTTACAACTGACATCAGGCGG
TCTGTTTTTTAATGCCTTAAAGAATGACAAAGAAAATTTCACTGTTTTACAAACCATTCGCCAGCAGCAACCCACGCTGA
ATGGCAGCTGGGTCGCGTTGTTGCAGACGCGTAACACCCTCAACCGCGCGGGTATCCGCTACATGATGGATCAGAATAAT
ATTGGTAGCGGTTCAACCGTTGCTGAGCTGATGCAGAGTGCCAGTATTTCGCTGAAACAGGCGGAAAAAAACTGGGCGGA
TTACGAAGCGTTGCCGCGTGACCCGCGTCAGAGCACCGCCGCAGCGGCAGAGATCAAACGTAATTACGATATTTATCACA
ATGCGCTGGCGGAGCTGATCCAACTGTTAGGTGCAGGCAAAATCAACGAGTTCTTTGATCAGCCGACCCAGGGATATCAG
GACGGTTTCGAGAAGCAGTATGTGGCTTACATGGAGCAAAACGATCGGCTCTATGATATCGCCGTCAGCGATAACAATGC
CTCCTACAGCCAGGCGATGTGGATTCTGGTGGGCGTGATGATCGTCGTACTGGCGGTCATCTTCGCCGTCTGGTTCGGTA
TTAAAGCCTCGCTGGTAGCGCCAATGAATCGCCTGATTGACAGCATTCGTCATATTGCAGGCGGCGATCTGGTGAAACCG
ATTGAGGTGGATGGCTCTAATGAGATGGGGCAACTGGCAGAGAGTTTGCGCCATATGCAGGGAGAGCTGATGCGTACCGT
CGGTGATGTGCGCAACGGGGCCAATGCCATCTATAGCGGTGCCAGCGAAATCGCTACCGGCAATAATGATCTCTCTTCGC
GCACCGAGCAACAGGCCGCTTCGCTGGAAGAGACGGCAGCCAGCATGGAGCAACTGACCGCAACGGTGAAACAGAACGCC
GAGAATGCGCGCCAGGCCAGCCATCTGGCATTAAGTGCTTCTGAAACGGCGCAACGCGGCGGCAAAGTGGTAGATAACGT
GGTGCAGACTATGCGCGATATCTCCACCAGTTCGCAGAAAATCGCCGATATTATCAGCGTAATTGACGGCATTACCTTCC
AGACCAATATTCTGGCTTTGAACGCGGCGGTTGAAGCAGCGCGTGCGGGTGAGCAAGGACGTGGTTTTGCGGTGGTTGCG
GGAGAAGTGCGTAATCTGGCCCAGCGTAGCGCCCAGGCGGTTCGTGAAATTAAAAGCCTGATTGAAGACTCGGTGGGGAA
AGTGGATGTTGGCTCTACGCTGGTCGAAAGCGCCGGGGAAACAATGGCGGAGATTGTCAGTGCTGTGACCCGCGTGACGG
ACATTATGGGCGAAATAGCTTCTGCTTCTGATGAGCAGAGCCGTGGTATCGATCAGGTTGGCTTAGCGGTTGCTGAGATG
GACCGGGTAACTCAACAGAACGCCGCGCTGGTGGAAGAATCTGCCGCTGCCGCCGCCGCGCTGGAAGAGCAGGCCAGTCG
CCTGACCGAAGCTGTGGCAGTGTTCCGGATTCAGCAACAGCAGCAACAGCAGCGTGAAACATCGGCTGTGGTAAAAACCG
TGACGCCAGCTACGCCGCGTAAAATGGCAGTGGCAGATAGCGGGGAGAACTGGGAAACGTTTTAA

Upstream 100 bases:

>100_bases
CCAGCGCCTGGTTTTTCCATGGATGGCGGGTTACACCTTTTCATAAAGTTTTTGCTTTCCAGGCCGAAAATCTTGCATCG
GTCCACAGGAAAGAGAAACC

Downstream 100 bases:

>100_bases
TCGCCATAAAAATGCCCGATAAGCAAAATGTTATCGGGCATAGGGAGTTTAATCTTTACGCGGGTCGTTGATCGGCTGGC
GAACCAGGAAGATGTACGCC

Product: methyl-accepting chemotaxis protein I, serine sensor receptor

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQPTLNGSWVALLQTRNTLNRAGIRYMMDQNN
IGSGSTVAELMQSASISLKQAEKNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
DGFEKQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKP
IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNA
ENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGITFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQAVREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
DRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRIQQQQQQQRETSAVVKTVTPATPRKMAVADSGENWETF

Sequences:

>Translated_554_residues
MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQPTLNGSWVALLQTRNTLNRAGIRYMMDQNN
IGSGSTVAELMQSASISLKQAEKNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
DGFEKQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKP
IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNA
ENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGITFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQAVREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
DRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRIQQQQQQQRETSAVVKTVTPATPRKMAVADSGENWETF
>Mature_554_residues
MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQPTLNGSWVALLQTRNTLNRAGIRYMMDQNN
IGSGSTVAELMQSASISLKQAEKNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
DGFEKQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKP
IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNA
ENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGITFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQAVREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
DRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRIQQQQQQQRETSAVVKTVTPATPRKMAVADSGENWETF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=554, Percent_Identity=98.1949458483755, Blast_Score=1052, Evalue=0.0,
Organism=Escherichia coli, GI1788195, Length=556, Percent_Identity=57.9136690647482, Blast_Score=570, Evalue=1e-163,
Organism=Escherichia coli, GI1788194, Length=531, Percent_Identity=46.3276836158192, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1787690, Length=536, Percent_Identity=42.7238805970149, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1789453, Length=323, Percent_Identity=39.6284829721362, Blast_Score=221, Evalue=9e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 59879; Mature: 59879

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50885 HAMP ; PS00538 CHEMOTAXIS_TRANSDUC_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQPTLNGSWVAL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHHCCCCCCCEEEE
LQTRNTLNRAGIRYMMDQNNIGSGSTVAELMQSASISLKQAEKNWADYEALPRDPRQSTA
EHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHH
AAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQDGFEKQYVAYMEQNDRLYDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEE
AVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKP
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHCCCCCCHHHHHHHHHH
SLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCHHHH
IADIISVIDGITFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAVREIKSL
HHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
IEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHH
DRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRIQQQQQQQRETSAVVKTVTPATPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KMAVADSGENWETF
CEEECCCCCCCCCC
>Mature Secondary Structure
MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQPTLNGSWVAL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHHCCCCCCCEEEE
LQTRNTLNRAGIRYMMDQNNIGSGSTVAELMQSASISLKQAEKNWADYEALPRDPRQSTA
EHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHH
AAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQDGFEKQYVAYMEQNDRLYDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEE
AVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKP
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHCCCCCCHHHHHHHHHH
SLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCHHHH
IADIISVIDGITFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAVREIKSL
HHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
IEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHH
DRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRIQQQQQQQRETSAVVKTVTPATPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KMAVADSGENWETF
CEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]