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The map label for this gene is hpcR

Identifier: 30065596

GI number: 30065596

Start: 4549533

End: 4549979

Strand: Direct

Name: hpcR

Synonym: S4655

Alternate gene names: 30065596

Gene position: 4549533-4549979 (Clockwise)

Preceding gene: 30065582

Following gene: 30065597

Centisome position: 98.92

GC content: 50.56

Gene sequence:

>447_bases
ATGCACGACTCACTAACCATTGCGTTGCTCCAGGCGCGAGAAGCGGCGATGAGTTATTTTCGCCCAATCGTTAAACGGCA
TAATTTGACTGAGCAACAGTGGCGCATCGTGCGTATTCTGGCGGAAAGCCCATCAATGGATTTTCACGATCTGGCGTATC
GCGCCTGCATTTTGCGCCCAAGCCTGACCGGGATCCTCACGCGGATGGAACGCGACGGTTTAGTGTTGCGATTAAAGCCG
ATCAATGATCAGCGGAAGCTCTATATCTCGCTGACCAAAGAGGGGCAGGCGCTGTATAACCGCGCTCAGACACAGATTGA
AGAAGCCTATCGGCAGATTGAAGCTCAGTTTACTGCCGAGAAAATGCAACAGTTAACCCATCTGTTAGAGGAATTTATTG
CTCTGGGCAATTCCCGACAAGAAGACATCCCGGGCGATAATGAATAA

Upstream 100 bases:

>100_bases
ATTTTGATAAAATGAAGAATTGCGGGGGCAGCTCAGTCCCGGTAACGTGATGATTAATTGTTTCTATATTAATGATTTTG
AATTTTTCAGGGGAAAGATA

Downstream 100 bases:

>100_bases
CTTTTTAGTATCTGATAACCAGCGCCTGGTTTTTCCATGGATGGCGGGTTACACCTTTTCATAAAGTTTTTGCTTTCCAG
GCCGAAAATCTTGCATCGGT

Product: regulator of the 4HPA-hydroxylase operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MHDSLTIALLQAREAAMSYFRPIVKRHNLTEQQWRIVRILAESPSMDFHDLAYRACILRPSLTGILTRMERDGLVLRLKP
INDQRKLYISLTKEGQALYNRAQTQIEEAYRQIEAQFTAEKMQQLTHLLEEFIALGNSRQEDIPGDNE

Sequences:

>Translated_148_residues
MHDSLTIALLQAREAAMSYFRPIVKRHNLTEQQWRIVRILAESPSMDFHDLAYRACILRPSLTGILTRMERDGLVLRLKP
INDQRKLYISLTKEGQALYNRAQTQIEEAYRQIEAQFTAEKMQQLTHLLEEFIALGNSRQEDIPGDNE
>Mature_148_residues
MHDSLTIALLQAREAAMSYFRPIVKRHNLTEQQWRIVRILAESPSMDFHDLAYRACILRPSLTGILTRMERDGLVLRLKP
INDQRKLYISLTKEGQALYNRAQTQIEEAYRQIEAQFTAEKMQQLTHLLEEFIALGNSRQEDIPGDNE

Specific function: Repressor for the homoprotocatechuate catabolic pathway hpc operon

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPCR_ECOLX (P62573)

Other databases:

- EMBL:   S56952
- EMBL:   Z37980
- PIR:   S30280
- ProteinModelPortal:   P62573
- SMR:   P62573
- GO:   GO:0005622
- InterPro:   IPR012712
- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00598
- SMART:   SM00347
- TIGRFAMs:   TIGR02337

Pfam domain/function: PF01047 MarR

EC number: NA

Molecular weight: Translated: 17255; Mature: 17255

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01117 HTH_MARR_1; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDSLTIALLQAREAAMSYFRPIVKRHNLTEQQWRIVRILAESPSMDFHDLAYRACILRP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
SLTGILTRMERDGLVLRLKPINDQRKLYISLTKEGQALYNRAQTQIEEAYRQIEAQFTAE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KMQQLTHLLEEFIALGNSRQEDIPGDNE
HHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MHDSLTIALLQAREAAMSYFRPIVKRHNLTEQQWRIVRILAESPSMDFHDLAYRACILRP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
SLTGILTRMERDGLVLRLKPINDQRKLYISLTKEGQALYNRAQTQIEEAYRQIEAQFTAE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KMQQLTHLLEEFIALGNSRQEDIPGDNE
HHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8384293; 8550403