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The map label for this gene is sugE

Identifier: 30065525

GI number: 30065525

Start: 4473305

End: 4473772

Strand: Direct

Name: sugE

Synonym: S4571

Alternate gene names: 30065525

Gene position: 4473305-4473772 (Clockwise)

Preceding gene: 30065524

Following gene: 30065532

Centisome position: 97.26

GC content: 52.78

Gene sequence:

>468_bases
GTGCCGTTTGTTTTTTCTGCGATCGTCATAAAGGTAATAGTTGAAATTCCCCTGCCACCTGGCAAAATATCCGTTCAACC
ATCAGCTTTGCAGGACGACCTGCAAACGCCTCTTTTCACCGGGGACGGCCCCAAATTTCCGGAGCCTGATATGTCCTGGA
TTATCTTAGTTATTGCTGGTCTGCTGGAAGTGGTATGGGCCGTTGGCCTGAAATATACCCACGGCTTTAGCCGTTTGACG
CCGAGTGTTATTACCGTGACGGCGATGATAGTCAGTATGGCGCTACTTGCCTGGGCGATGAAATCGTTACCGGTAGGGAC
GGCTTATGCCGTGTGGACGGGTATTGGCGCAGTCGGCGCGGCCATCACCGGCATTGTGCTGCTCGGTGAGTCCGCTAACC
CGATGCGTCTGGCGAGTCTGGCGTTAATCGTATTGGGGATTATTGGTCTGAAACTCAGCACTCACTAA

Upstream 100 bases:

>100_bases
ACGCGTGGCGTTGGTGAAGACATTTCTGATGGCGGTAACGCGATTTCTGGCGCAGCAACGAAAGCGCAGCAATAAGCAAT
AACGGTACGACAGCAGTGTC

Downstream 100 bases:

>100_bases
CTACCGGGCTGCTGTACCCAAATAAACTTACTGACATCAAACCCTTCCCGGGTCGCGACTGCCAGCATCTCCTGTTTCAC
TTCGTCAGAAATGGTTGGCG

Product: suppresser of groEL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MPFVFSAIVIKVIVEIPLPPGKISVQPSALQDDLQTPLFTGDGPKFPEPDMSWIILVIAGLLEVVWAVGLKYTHGFSRLT
PSVITVTAMIVSMALLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKLSTH

Sequences:

>Translated_155_residues
MPFVFSAIVIKVIVEIPLPPGKISVQPSALQDDLQTPLFTGDGPKFPEPDMSWIILVIAGLLEVVWAVGLKYTHGFSRLT
PSVITVTAMIVSMALLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKLSTH
>Mature_154_residues
PFVFSAIVIKVIVEIPLPPGKISVQPSALQDDLQTPLFTGDGPKFPEPDMSWIILVIAGLLEVVWAVGLKYTHGFSRLTP
SVITVTAMIVSMALLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKLSTH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=105, Percent_Identity=100, Blast_Score=199, Evalue=8e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 16273; Mature: 16142

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFVFSAIVIKVIVEIPLPPGKISVQPSALQDDLQTPLFTGDGPKFPEPDMSWIILVIAG
CCHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
LLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMALLAWAMKSLPVGTAYAVWTGIGAVGA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AITGIVLLGESANPMRLASLALIVLGIIGLKLSTH
HHHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFVFSAIVIKVIVEIPLPPGKISVQPSALQDDLQTPLFTGDGPKFPEPDMSWIILVIAG
CHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
LLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMALLAWAMKSLPVGTAYAVWTGIGAVGA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AITGIVLLGESANPMRLASLALIVLGIIGLKLSTH
HHHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]