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The map label for this gene is srlR

Identifier: 30064066

GI number: 30064066

Start: 2797355

End: 2798128

Strand: Direct

Name: srlR

Synonym: S2921

Alternate gene names: 30064066

Gene position: 2797355-2798128 (Clockwise)

Preceding gene: 30064065

Following gene: 161486447

Centisome position: 60.82

GC content: 48.71

Gene sequence:

>774_bases
ATGAAACCTCGTCAGCGTCAGGCCGCCATTCTGGAGTATCTGCAAAAGCAGGGTAAATGCTCGGTTGAAGAATTGGCGCA
ATACTTTGACACCACAGGCACAACCATTCGCAAAGATCTGGTCATTCTGGAACATGCCGGAACCGTCATTCGTACTTATG
GCGGAGTGGTGTTGAATAAAGAGGAATCCGATCCGCCTATCGATCATAAAACGCTCATCAACACCCACAAGAAAGAGCTG
ATTGCAGAAGCTGCCGTTAGTTTTATCCATGATGGCGATTCGATCATTCTTGATGCTGGCAGTACCGTTTTGCAGATTGT
TCCCCTGCTCTCGCGCTTTAATAACATCACGGTGATGACCAACAGCCTGCATATCGTCAATGCGCTATCCGAACTGGATA
ACGAACAAACTATCCTGATGCCAGGCGGAACATTTCGCAAAAAATCGGCCTCATTTCACGGGCAACTGGCAGAGAATGCC
TTCGAGCATTTCACCTTCGATAAATTGTTTATGGGCACCGACGGCATCGATCTCAATGCGGGCGTAACCACGTTCAACGA
GGTTTATACCGTCAGTAAGGCAATGTGCAATGCCGCGCGCGAAGTGATTTTGATGGCGGACTCATCAAAGTTTGGCCGTA
AAAGCCCCAACGTAGTTTGCAGTCTTGAAAGCGTCGATAAGCTAATTACCGACGCAGGTATCGATCCGGCGTTTCGTCAG
GCGCTGGAAGAGAAAGGGATCGATGTGATCATAACCGGAGAGAGCAATGAGTGA

Upstream 100 bases:

>100_bases
TCTATCATTGGCGCTTAAACTGAAACGTGGATAATTTCGTTGTGAATGTTACTTGCTTGCGAAGTTATCATTTTGAAACC
TAAATCAGGTAATCACGCCC

Downstream 100 bases:

>100_bases
AGCACTACTGAACACGGGACGTCAGACGTTAATGCTGGAGTTGCAGGAAGCAAGCCGTTTACCGGAACGTCTGGGCGATG
ATTTTGTTCGCGCCGCCAAT

Product: DNA-bindng transcriptional repressor SrlR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKEL
IAEAAVSFIHDGDSIILDAGSTVLQIVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNVVCSLESVDKLITDAGIDPAFRQ
ALEEKGIDVIITGESNE

Sequences:

>Translated_257_residues
MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKEL
IAEAAVSFIHDGDSIILDAGSTVLQIVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNVVCSLESVDKLITDAGIDPAFRQ
ALEEKGIDVIITGESNE
>Mature_257_residues
MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKEL
IAEAAVSFIHDGDSIILDAGSTVLQIVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNVVCSLESVDKLITDAGIDPAFRQ
ALEEKGIDVIITGESNE

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=257, Percent_Identity=99.6108949416342, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=35.8267716535433, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1789829, Length=251, Percent_Identity=29.8804780876494, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=29.6442687747036, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=31.1965811965812, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082344, Length=254, Percent_Identity=27.1653543307087, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787540, Length=247, Percent_Identity=29.9595141700405, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790753, Length=251, Percent_Identity=28.2868525896414, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790635, Length=257, Percent_Identity=24.5136186770428, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=27.7056277056277, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787063, Length=231, Percent_Identity=24.6753246753247, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28218; Mature: 28218

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNK
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHEEEEECCCCEEEHHCCEEEEC
EESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIILDAGSTVLQIVPLLSRFNNITVMT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEEE
NSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENAFEHFTFDKLFMGTDGIDLNA
CCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHEECCCCCCCCC
GVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNVVCSLESVDKLITDAGIDPAFRQ
CCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHCCCCHHHHH
ALEEKGIDVIITGESNE
HHHHCCCEEEEECCCCC
>Mature Secondary Structure
MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNK
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHEEEEECCCCEEEHHCCEEEEC
EESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIILDAGSTVLQIVPLLSRFNNITVMT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEEE
NSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENAFEHFTFDKLFMGTDGIDLNA
CCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHEECCCCCCCCC
GVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNVVCSLESVDKLITDAGIDPAFRQ
CCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHCCCCHHHHH
ALEEKGIDVIITGESNE
HHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]