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The map label for this gene is emrK [H]

Identifier: 30062864

GI number: 30062864

Start: 1404902

End: 1405297

Strand: Direct

Name: emrK [H]

Synonym: S1443

Alternate gene names: 30062864

Gene position: 1404902-1405297 (Clockwise)

Preceding gene: 30062861

Following gene: 30062865

Centisome position: 30.55

GC content: 49.24

Gene sequence:

>396_bases
GTGGTTCGTGCGCCGATTGATGGCATTGTCGCAAACCGCAGCGCCCATACAGGCAGTTGGGTGGAAGGCGGCACATCGTT
AGTTTCACTAGTACCAGTCAGTGAGTTGTGGGTTGATGCAAATTATAAAGAAAACCAAATAGCGGGAATGAAGCCAGGAA
TGAAGGCTGAGATCCGTGCTGATATTCTCAAAGGGGAAGTGTTTCACGGTCACATTGAAAGCCTTTCCCCAGCGACAGGA
GCCAGTTTCAGCTTGATTCCGATAGAAAATGCCACTGGCAATTTCACCAAAATTGTTCAGCGTGTCCCGGTACGGATTGC
ATTTGACGACGCAAAGGAATTAAAGCAACTTCTTCGCCCGGGACTGTCCGTCACCGTCAGTGTTGATGAGAGATGA

Upstream 100 bases:

>100_bases
CCTTAATAAAACAGGTCCTCAGAGCATACATATTCTGCGGAGCGTGCGGCAACAACAGGACGAACAGGGGCGGTTTTCAA
TTTGCAGCCGTCAGGCTGCC

Downstream 100 bases:

>100_bases
TGTCTATGCGTAAACATATTGCTTTCGCCAGTATGTGTATGGGATTATTTATTGCTCAGCTTGATATTCAAATTGTATCG
TCATCCCTAAATGAAATAGG

Product: putative secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MVRAPIDGIVANRSAHTGSWVEGGTSLVSLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATG
ASFSLIPIENATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLSVTVSVDER

Sequences:

>Translated_131_residues
MVRAPIDGIVANRSAHTGSWVEGGTSLVSLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATG
ASFSLIPIENATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLSVTVSVDER
>Mature_131_residues
MVRAPIDGIVANRSAHTGSWVEGGTSLVSLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATG
ASFSLIPIENATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLSVTVSVDER

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=132, Percent_Identity=42.4242424242424, Blast_Score=117, Evalue=3e-28,
Organism=Escherichia coli, GI1789041, Length=128, Percent_Identity=45.3125, Blast_Score=110, Evalue=3e-26,
Organism=Escherichia coli, GI1789637, Length=118, Percent_Identity=31.3559322033898, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 14121; Mature: 14121

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRAPIDGIVANRSAHTGSWVEGGTSLVSLVPVSELWVDANYKENQIAGMKPGMKAEIRA
CCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEHHHHEECCCCCCCEECCCCCCCCHHHHH
DILKGEVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAFDDAKELKQLLRP
HHHCCCEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCEEEEECCHHHHHHHHCC
GLSVTVSVDER
CCEEEEEECCC
>Mature Secondary Structure
MVRAPIDGIVANRSAHTGSWVEGGTSLVSLVPVSELWVDANYKENQIAGMKPGMKAEIRA
CCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEHHHHEECCCCCCCEECCCCCCCCHHHHH
DILKGEVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAFDDAKELKQLLRP
HHHCCCEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCEEEEECCHHHHHHHHCC
GLSVTVSVDER
CCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]