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The map label for this gene is mdtN [H]

Identifier: 30062861

GI number: 30062861

Start: 1402582

End: 1403229

Strand: Direct

Name: mdtN [H]

Synonym: S1439

Alternate gene names: 30062861

Gene position: 1402582-1403229 (Clockwise)

Preceding gene: 30062856

Following gene: 30062864

Centisome position: 30.5

GC content: 44.6

Gene sequence:

>648_bases
ATGATAATTTCTAAAAAACAGCTTATTGGGGTGGTAGCGATCGGTATTCTTTTGACTGGCGTTGTCTTTTTTATCTGGAG
GGTAAGCAAAGGAAGATTTATACAGACGACGGATGATGCTTACATTGGTGGTAATATCACCACGGTGGCAAGTAAAGTTT
CTGGTTATATTTCTGCTATAGAGGTGCGCGATAATCAGAGCGTAAAAAAAGGCGATATTATCCTGCGTCTCGATGATCGG
GATTATCGTGCAAATGTCGCCAGGCTTGAGGCAAAAATAAAAAGTAGCAAAGCCAATCTCGAAGGCATTCAAGCCACTAT
TACGATGCAGCAGTCGATAATTCAAAGTGCCAGTGAAACATGGCAGGCAGTAAAACATGAGGAGCAAAAGCGCCTGCGAG
ATACTGAACGTTATGAAAAACTCGCACAATCAGCGGCAATATCGCAACAAATTATTGATAACGCCAGGTTTGACTACCAG
CAGGTCGCAGCAAAGGAGCGCAAAGCCGCGAACGATTTCCTGGTGGAGAAGCAACGGCTGGCAGTTTTATCTGCTCAGGA
AGAAAACGTACGTGCGAGTATCGAAGAAGTTCAGGCCGCTTTGACTCAGGCACTACTGGATCTGGAATATACCCTTGTTC
ACGTATAG

Upstream 100 bases:

>100_bases
TCATTTACAGTAGGTATTTTGTCAGAAATCATCAAATAAGCCATGTTAAATTTTAAATATGACGTATGCAAGTTTCCGGA
TATATACGGTGTAAAGAGTG

Downstream 100 bases:

>100_bases
GAAATTGAAAAACCAGACGATACCGCTGTCCACGCCTTATGCCACGTGAGCTTTTCTGCTTTTCCCTCCACTCCGGTGTT
TTCTCTCTCTGCATGGTCGA

Product: putative secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MIISKKQLIGVVAIGILLTGVVFFIWRVSKGRFIQTTDDAYIGGNITTVASKVSGYISAIEVRDNQSVKKGDIILRLDDR
DYRANVARLEAKIKSSKANLEGIQATITMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQ
QVAAKERKAANDFLVEKQRLAVLSAQEENVRASIEEVQAALTQALLDLEYTLVHV

Sequences:

>Translated_215_residues
MIISKKQLIGVVAIGILLTGVVFFIWRVSKGRFIQTTDDAYIGGNITTVASKVSGYISAIEVRDNQSVKKGDIILRLDDR
DYRANVARLEAKIKSSKANLEGIQATITMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQ
QVAAKERKAANDFLVEKQRLAVLSAQEENVRASIEEVQAALTQALLDLEYTLVHV
>Mature_215_residues
MIISKKQLIGVVAIGILLTGVVFFIWRVSKGRFIQTTDDAYIGGNITTVASKVSGYISAIEVRDNQSVKKGDIILRLDDR
DYRANVARLEAKIKSSKANLEGIQATITMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQ
QVAAKERKAANDFLVEKQRLAVLSAQEENVRASIEEVQAALTQALLDLEYTLVHV

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=134, Percent_Identity=32.089552238806, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 24081; Mature: 24081

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISKKQLIGVVAIGILLTGVVFFIWRVSKGRFIQTTDDAYIGGNITTVASKVSGYISAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCHHHHHHHHHHHHHEE
EVRDNQSVKKGDIILRLDDRDYRANVARLEAKIKSSKANLEGIQATITMQQSIIQSASET
EECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
WQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQQVAAKERKAANDFLVEKQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AVLSAQEENVRASIEEVQAALTQALLDLEYTLVHV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
>Mature Secondary Structure
MIISKKQLIGVVAIGILLTGVVFFIWRVSKGRFIQTTDDAYIGGNITTVASKVSGYISAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCHHHHHHHHHHHHHEE
EVRDNQSVKKGDIILRLDDRDYRANVARLEAKIKSSKANLEGIQATITMQQSIIQSASET
EECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
WQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQQVAAKERKAANDFLVEKQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AVLSAQEENVRASIEEVQAALTQALLDLEYTLVHV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]