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The map label for this gene is dmsC

Identifier: 30062383

GI number: 30062383

Start: 890253

End: 891044

Strand: Direct

Name: dmsC

Synonym: S0896

Alternate gene names: 30062383

Gene position: 890253-891044 (Clockwise)

Preceding gene: 30062382

Following gene: 30062385

Centisome position: 19.36

GC content: 55.3

Gene sequence:

>792_bases
ATGGGAAGTGGATGGCATGAATGGCCGCTGATGATCTTCACGGTCTTCGGGCAATGTGTGGCGGGTGGTTTTATCGTTCT
GGCTTTGGCGCTGCTCAAAGGCGACCTGCGAGCAGAAGCCCAGCAGCGTGTTATCGCCTGCATGTTTGGCTTATGGGTAC
TGATGGGCATTGGCTTTATCGCCTCTATGCTCCATCTTGGTTCACCGATGCGCGCCTTTAACTCGCTCAACCGGGTAGGG
GCTTCAGCACTCAGTAACGAAATCGCCAGCGGTTCGATCTTTTTTGCTGTAGGCGGCATCGGCTGGTTGCTGGCAATGCT
GAAAAAGCTGTCACCGGCATTGCGTACGCTATGGCTGGTGGTGACGATGGTTCTTGGCGTCGTCTTTGTCTGGATGATGG
TGCGTGTGTATAACAGCATTGATACCGTTCCGACCTGGTACAGCATCTGGACGCCGATGGGCTGGGCGATGCGTCTGCTG
CCAGCCATTTCTGTACTGGCACTGGTGGTGAGTGGCGTGATGTCAGTGATGCAGGGCACAGAGCTGGCAACTATTCATAG
TTCTGTGCAGCAGGCCGCAGCGCTGGTGCCGGACTATGGTGCGCTGATGTCCTGGCGGATCGTGCTTTTGGCCGTTGCCC
TGTGCTTGTGGATTGCACCACAGCTAAAAGGTTATCAGCCTGCGGTTCCGCTACTATCCGTCTCATTCATTCTGCTTCTG
GCAGGGGAATTAATCGGTCGCGGCGTATTCTATGGTTTGCATATGACCGTGGGGATGGCCGTCGCAAGCTAA

Upstream 100 bases:

>100_bases
GCTCACTTTACCAAACCGAATATTGTGATCAAACCCAATGCCAATAGCCGCCCGACCGGGGATACCACTGGCTATCTGGC
AAACCCGAAGGAGGTGTGAG

Downstream 100 bases:

>100_bases
TCAGTAACAACCGGGGTTTCGGCCCCGGTTCTCTTTTATTTCTGCTTCGTTAACGTGTCATAACTGGTCATCAAATTACG
ATAATCAGGAATATGGTTAG

Product: anaerobic dimethyl sulfoxide reductase subunit C

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase anchor subunit [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRVIACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVG
ASALSNEIASGSIFFAVGGIGWLLAMLKKLSPALRTLWLVVTMVLGVVFVWMMVRVYNSIDTVPTWYSIWTPMGWAMRLL
PAISVLALVVSGVMSVMQGTELATIHSSVQQAAALVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLL
AGELIGRGVFYGLHMTVGMAVAS

Sequences:

>Translated_263_residues
MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRVIACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVG
ASALSNEIASGSIFFAVGGIGWLLAMLKKLSPALRTLWLVVTMVLGVVFVWMMVRVYNSIDTVPTWYSIWTPMGWAMRLL
PAISVLALVVSGVMSVMQGTELATIHSSVQQAAALVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLL
AGELIGRGVFYGLHMTVGMAVAS
>Mature_262_residues
GSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRVIACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGA
SALSNEIASGSIFFAVGGIGWLLAMLKKLSPALRTLWLVVTMVLGVVFVWMMVRVYNSIDTVPTWYSIWTPMGWAMRLLP
AISVLALVVSGVMSVMQGTELATIHSSVQQAAALVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLLA
GELIGRGVFYGLHMTVGMAVAS

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it [H]

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli ynfH [H]

Homologues:

Organism=Escherichia coli, GI1787123, Length=287, Percent_Identity=90.2439024390244, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1787873, Length=285, Percent_Identity=53.3333333333333, Blast_Score=270, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007059 [H]

Pfam domain/function: PF04976 DmsC [H]

EC number: NA

Molecular weight: Translated: 28346; Mature: 28214

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRVIACMFGLWVLMGIGFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGWLLAMLKKLSPALRTLWLV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTMVLGVVFVWMMVRVYNSIDTVPTWYSIWTPMGWAMRLLPAISVLALVVSGVMSVMQGT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ELATIHSSVQQAAALVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AGELIGRGVFYGLHMTVGMAVAS
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 8429002; 2170332 [H]