Click here to switch to the map view.

The map label for this gene is tolQ

Identifier: 30062100

GI number: 30062100

Start: 577485

End: 578177

Strand: Reverse

Name: tolQ

Synonym: S0573

Alternate gene names: 30062100

Gene position: 578177-577485 (Counterclockwise)

Preceding gene: 30062101

Following gene: 30062099

Centisome position: 12.57

GC content: 50.07

Gene sequence:

>693_bases
GTGACTGACATGAATATCCTTGATTTGTTCCTGAAGGCTAGCCTTCTGGTTAAACTTATCATGTTGATTTTGATTGGTTT
TTCAATCGCATCCTGGGCCATTATTATCCAGCGAACCCGTATTCTTAACGCAGCGGCGCGTGAAGCCGAAGCGTTTGAAG
ATAAATTCTGGTCTGGAATCGAACTCTCTCGCCTCTATCAAGAGAGTCAGGGGAAACGGGATAATCTGACTGGTTCGGAA
CAAATCTTTTACAGCGGGTTCAAAGAGTTTGTGCGCCTGCATCGTGCCAATAGCCATGCGCCGGAAGCCGTAGTGGAAGG
GGCGTCGCGTGCTATGCGTATCTCCATGAACCGTGAACTTGAAAATCTGGAAACGCACATTCCGTTCCTCGGTACGGTTG
GCTCCATCAGCCCGTATATTGGTCTGTTTGGTACGGTCTGGGGGATCATGCACGCCTTTATCGCCCTCGGGGCGGTAAAA
CAAGCAACACTGCAAATGGTTGCGCCCGGTATCGCAGAAGCGTTGATTGCGACGGCAATTGGTCTGTTCGCCGCAATTCC
GGCGGTAATGGCTTATAACCGTCTCAACCAGCGCGTAAACAAACTGGAACTGAATTACGACAACTTTATGGAAGAGTTTA
CCGCGATTCTGCACCGCCAGGCGTTTACCGTTAGCGAGAGCAACAAGGGGTAA

Upstream 100 bases:

>100_bases
ATACTTTGCTGAATGAAGCAGAGGTTCTGGTTGTTTGCGTTGACCCACTCAAAATGAAGCCTCGTGCGCTTCCCAAGTCT
ATTGTCGCGGAGTTTAAGCA

Downstream 100 bases:

>100_bases
GCCATGGCCAGAGCGCGTGGACGAGGTCGTCGCGATCTCAAGTCCGAAATCAACATTGTTCCGTTGCTGGACGTACTGCT
GGTGCTGTTGCTGATCTTTA

Product: colicin uptake protein TolQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSE
QIFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG

Sequences:

>Translated_230_residues
MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSE
QIFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG
>Mature_229_residues
TDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSEQ
IFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVKQ
ATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG

Specific function: Involved in the tonB-independent uptake of proteins

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family

Homologues:

Organism=Escherichia coli, GI1786958, Length=230, Percent_Identity=100, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1789381, Length=205, Percent_Identity=34.1463414634146, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TOLQ_ECO57 (P0ABV0)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D90725
- PIR:   E85576
- RefSeq:   NP_286465.1
- RefSeq:   NP_308799.1
- ProteinModelPortal:   P0ABV0
- EnsemblBacteria:   EBESCT00000027439
- EnsemblBacteria:   EBESCT00000058492
- GeneID:   917505
- GeneID:   957868
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0905
- KEGG:   ecs:ECs0772
- GeneTree:   EBGT00050000010126
- HOGENOM:   HBG681852
- OMA:   YAGFKEY
- ProtClustDB:   PRK10801
- BioCyc:   ECOL83334:ECS0772-MONOMER
- InterPro:   IPR002898
- InterPro:   IPR014163
- TIGRFAMs:   TIGR02796

Pfam domain/function: PF01618 MotA_ExbB

EC number: NA

Molecular weight: Translated: 25598; Mature: 25467

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x107f9c20)-; HASH(0x10cd5514)-; HASH(0x11240930)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ELSRLYQESQGKRDNLTGSEQIFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNREL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVKQATLQMVAPGIAEALIATAI
HHHHHHCCHHCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure 
TDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ELSRLYQESQGKRDNLTGSEQIFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNREL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVKQATLQMVAPGIAEALIATAI
HHHHHHCCHHCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796