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The map label for this gene is tolR

Identifier: 30062099

GI number: 30062099

Start: 577053

End: 577481

Strand: Reverse

Name: tolR

Synonym: S0572

Alternate gene names: 30062099

Gene position: 577481-577053 (Counterclockwise)

Preceding gene: 30062100

Following gene: 30062098

Centisome position: 12.56

GC content: 51.75

Gene sequence:

>429_bases
ATGGCCAGAGCGCGTGGACGAGGTCGTCGCGATCTCAAGTCCGAAATCAACATTGTTCCGTTGCTGGACGTACTGCTGGT
GCTGTTGCTGATCTTTATGGCGACAGCGCCCATCATCACCCAGAGCGTGGAGGTCGATCTGCCAGACGCTACTGAATCAC
AGGCGGTGAGCAGTAACGATAATCCGCCAGTGATTGTTGAAGTGTCTGGTATTGGTCAGTACACCGTGGTGGTTGAGAAA
GATCGCCTGGAGCGTTTACCACCAGAGCAGGTGGTGGCGGAAGTGTCCAGCCGTTTCAAGGCCAACCCGAAAACGGTCTT
TCTGATCGGTGGCGCAAAAGATGTGCCTTACGATGAAATAATTAAAGCACTGAACTTGTTACATAGTGCGGGTGTGAAAT
CGGTTGGTTTAATGACGCAGCCTATCTAA

Upstream 100 bases:

>100_bases
AAACAAACTGGAACTGAATTACGACAACTTTATGGAAGAGTTTACCGCGATTCTGCACCGCCAGGCGTTTACCGTTAGCG
AGAGCAACAAGGGGTAAGCC

Downstream 100 bases:

>100_bases
ACATCTGCGTTTCCCTTGCTTGAAAGAGAGCGGGTAACAGGCGAACAGTTTTTGGAAACCGAGAGTGTCAAAGGCAACCG
AACAAAACGACAAGCTCAAG

Product: colicin uptake protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEK
DRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI

Sequences:

>Translated_142_residues
MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEK
DRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI
>Mature_141_residues
ARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKD
RLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). [C]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family

Homologues:

Organism=Escherichia coli, GI1786959, Length=142, Percent_Identity=100, Blast_Score=281, Evalue=9e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TOLR_ECO57 (P0ABV8)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   E90725
- PIR:   F85576
- RefSeq:   NP_286466.1
- RefSeq:   NP_308800.1
- ProteinModelPortal:   P0ABV8
- SMR:   P0ABV8
- MINT:   MINT-100173
- EnsemblBacteria:   EBESCT00000026673
- EnsemblBacteria:   EBESCT00000057933
- GeneID:   917504
- GeneID:   957870
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0906
- KEGG:   ecs:ECs0773
- GeneTree:   EBGT00050000009885
- HOGENOM:   HBG729503
- OMA:   YYLDIGS
- ProtClustDB:   PRK11024
- BioCyc:   ECOL83334:ECS0773-MONOMER
- InterPro:   IPR014168
- InterPro:   IPR003400
- TIGRFAMs:   TIGR02801

Pfam domain/function: PF02472 ExbD

EC number: NA

Molecular weight: Translated: 15383; Mature: 15252

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1113e3f8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSND
CCCCCCCCCHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCC
NPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEI
CCCEEEEECCCCEEEEEEECHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
IKALNLLHSAGVKSVGLMTQPI
HHHHHHHHHCCCCCCCCCCCCH
>Mature Secondary Structure 
ARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSND
CCCCCCCCHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCC
NPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEI
CCCEEEEECCCCEEEEEEECHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
IKALNLLHSAGVKSVGLMTQPI
HHHHHHHHHCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796