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The map label for this gene is purM [H]

Identifier: 29349619

GI number: 29349619

Start: 5547969

End: 5549135

Strand: Reverse

Name: purM [H]

Synonym: BT_4211

Alternate gene names: 29349619

Gene position: 5549135-5547969 (Counterclockwise)

Preceding gene: 29349620

Following gene: 29349618

Centisome position: 88.64

GC content: 46.62

Gene sequence:

>1167_bases
ATGAGTAATCAACGATACATGATGCGGGGCGTAAGCGCATCAAAAGAAGATGTGCACAACGCCATCAAGAACATCGACAA
AGGAATTTTCCCAAAAGCATTCTGCAAAATTATTCCCGATATACTGGGTGGGGACCCGGAATATTGCAACATCATGCACG
CCGACGGCGCCGGAACCAAATCTTCCCTTGCTTATATGTACTGGAAAGAAACAGGCGATTTGTCTGTGTGGAAAGGTATT
GCACAGGACGCATTGATTATGAATATCGACGACCTTCTTTGTGTAGGCGCTGTAGACAATATCCTCGTTTCTTCAACTAT
CGGACGCAATAAACTGTTGATTCCCGGCGAAGTAATCTCCGCTATCATCAACGGAACAGACGAATTGCTGGCTGAACTCC
GTGAAATGGGTGTAGGTGTATATGCTACCGGTGGCGAGACTGCTGATGTCGGCGACTTGGTTCGTACTATTATCGTAGAC
TCTACCGTAACCTGCCGCATGAAACGCTCGGACGTTATTAACAATGCCAATATCCGTCCGGGAGATGTCATTGTAGGCCT
TGCTTCTTACGGACAGGCTACCTATGAAAAAGAATATAACGGAGGTATGGGCAGCAACGGTCTGACAAGTGCCCGCCACG
ACGTTTTCGGCAAATACCTCGCAGAGAAATATCCGGAAAGCTATGATGCCGCCGTACCTGAAGAACTGGTTTACTCCGGA
GGATTAAAACTGACAGATACTGTAGAGGATTCTCCAATTGACGCAGGTAAACTGGTACTCTCTCCTACCCGCACCTATGC
TCCGGTAGTGAAAAAGCTACTTGACACCTTACGTCCGGAAATCCACGGTATGGTTCATTGCTCCGGTGGTGCGCAAACCA
AAGTGCTGCATTTCGTAGAAAATGTCCGTGTAGTAAAAGACAATCTTTTCCCTGTTCCTCCTCTGTTCAAGACTATTCAG
GAACAAAGCGGTACAGACTGGGCGGAAATGTACAAGGTATTCAATATGGGACACCGTCTTGAAGTTTACCTGTCACCGGA
ACATGCAGAAGAAGTGATCGCTATTTCCGAATCATTCGGCATTCCTGCACAGATAGTAGGACGTATCGAAGCGTGTGACC
AGACTGAATTAATCATTAAAAGCGAGTTCGGAGAATTCAGATACTAA

Upstream 100 bases:

>100_bases
TTTATTCTTCTTCCGGACGAAGCTTGATAAACAAATAGTTGGCTGTACGAAAAAAAAGCAGTACTTTTGCAGCCGTATAC
AAAAAATAATTCTTTAACTC

Downstream 100 bases:

>100_bases
AGAATGGCAGATAACAGTACCATATTAGAAAAACTAGACGGACTTGTAGCCCGTTTTGAAGAAATATCTACCCTCATCAC
CGACCCGGCAGTAATTGCCG

Product: putative phosphoribosylformylglycinamidine cyclo-ligase

Products: NA

Alternate protein names: AIR synthase; AIRS; Phosphoribosyl-aminoimidazole synthetase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSNQRYMMRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTKSSLAYMYWKETGDLSVWKGI
AQDALIMNIDDLLCVGAVDNILVSSTIGRNKLLIPGEVISAIINGTDELLAELREMGVGVYATGGETADVGDLVRTIIVD
STVTCRMKRSDVINNANIRPGDVIVGLASYGQATYEKEYNGGMGSNGLTSARHDVFGKYLAEKYPESYDAAVPEELVYSG
GLKLTDTVEDSPIDAGKLVLSPTRTYAPVVKKLLDTLRPEIHGMVHCSGGAQTKVLHFVENVRVVKDNLFPVPPLFKTIQ
EQSGTDWAEMYKVFNMGHRLEVYLSPEHAEEVIAISESFGIPAQIVGRIEACDQTELIIKSEFGEFRY

Sequences:

>Translated_388_residues
MSNQRYMMRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTKSSLAYMYWKETGDLSVWKGI
AQDALIMNIDDLLCVGAVDNILVSSTIGRNKLLIPGEVISAIINGTDELLAELREMGVGVYATGGETADVGDLVRTIIVD
STVTCRMKRSDVINNANIRPGDVIVGLASYGQATYEKEYNGGMGSNGLTSARHDVFGKYLAEKYPESYDAAVPEELVYSG
GLKLTDTVEDSPIDAGKLVLSPTRTYAPVVKKLLDTLRPEIHGMVHCSGGAQTKVLHFVENVRVVKDNLFPVPPLFKTIQ
EQSGTDWAEMYKVFNMGHRLEVYLSPEHAEEVIAISESFGIPAQIVGRIEACDQTELIIKSEFGEFRY
>Mature_387_residues
SNQRYMMRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTKSSLAYMYWKETGDLSVWKGIA
QDALIMNIDDLLCVGAVDNILVSSTIGRNKLLIPGEVISAIINGTDELLAELREMGVGVYATGGETADVGDLVRTIIVDS
TVTCRMKRSDVINNANIRPGDVIVGLASYGQATYEKEYNGGMGSNGLTSARHDVFGKYLAEKYPESYDAAVPEELVYSGG
LKLTDTVEDSPIDAGKLVLSPTRTYAPVVKKLLDTLRPEIHGMVHCSGGAQTKVLHFVENVRVVKDNLFPVPPLFKTIQE
QSGTDWAEMYKVFNMGHRLEVYLSPEHAEEVIAISESFGIPAQIVGRIEACDQTELIIKSEFGEFRY

Specific function: De novo purine biosynthesis; fifth step. [C]

COG id: COG0150

COG function: function code F; Phosphoribosylaminoimidazole (AIR) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788845, Length=384, Percent_Identity=24.4791666666667, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 180 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR004733
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.3.1 [H]

Molecular weight: Translated: 42439; Mature: 42308

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQRYMMRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTK
CCCCCHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
SSLAYMYWKETGDLSVWKGIAQDALIMNIDDLLCVGAVDNILVSSTIGRNKLLIPGEVIS
CCEEEEEEECCCCHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHH
AIINGTDELLAELREMGVGVYATGGETADVGDLVRTIIVDSTVTCRMKRSDVINNANIRP
HHHCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCC
GDVIVGLASYGQATYEKEYNGGMGSNGLTSARHDVFGKYLAEKYPESYDAAVPEELVYSG
CCEEEEEHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
GLKLTDTVEDSPIDAGKLVLSPTRTYAPVVKKLLDTLRPEIHGMVHCSGGAQTKVLHFVE
CCEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCHHHCEEEEECCCCHHHHHHHHH
NVRVVKDNLFPVPPLFKTIQEQSGTDWAEMYKVFNMGHRLEVYLSPEHAEEVIAISESFG
HHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCHHHHHHEEEHHCCC
IPAQIVGRIEACDQTELIIKSEFGEFRY
CCHHHHHHHHCCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SNQRYMMRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTK
CCCCHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
SSLAYMYWKETGDLSVWKGIAQDALIMNIDDLLCVGAVDNILVSSTIGRNKLLIPGEVIS
CCEEEEEEECCCCHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHH
AIINGTDELLAELREMGVGVYATGGETADVGDLVRTIIVDSTVTCRMKRSDVINNANIRP
HHHCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCC
GDVIVGLASYGQATYEKEYNGGMGSNGLTSARHDVFGKYLAEKYPESYDAAVPEELVYSG
CCEEEEEHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
GLKLTDTVEDSPIDAGKLVLSPTRTYAPVVKKLLDTLRPEIHGMVHCSGGAQTKVLHFVE
CCEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCHHHCEEEEECCCCHHHHHHHHH
NVRVVKDNLFPVPPLFKTIQEQSGTDWAEMYKVFNMGHRLEVYLSPEHAEEVIAISESFG
HHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCHHHHHHEEEHHCCC
IPAQIVGRIEACDQTELIIKSEFGEFRY
CCHHHHHHHHCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA