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The map label for this gene is cdsA [H]

Identifier: 29349414

GI number: 29349414

Start: 5218967

End: 5219809

Strand: Reverse

Name: cdsA [H]

Synonym: BT_4006

Alternate gene names: 29349414

Gene position: 5219809-5218967 (Counterclockwise)

Preceding gene: 29349415

Following gene: 29349410

Centisome position: 83.38

GC content: 44.96

Gene sequence:

>843_bases
TTGATTAGTAATTTTATAAAACGGGCCATTACGGGTATACTCTTTGTCGCCATTCTGGTGGGATGTATACTCTATAATTC
TTTCAGCTTCGGCATTCTGTTCATGGCGATCAGTGCACTGACGATCTATGAATTCGGACAGTTAATCAACAGCCGTGCAG
AAGGAGTCAACGTAAACAAAACCATTATCATGCTGGGAGGAGCTTACCTGTTCCTCGCAGTGATGGGATTCTGTATCGAC
GCAGCCGACTCCAAGATTTTCATTCCTTATTTGCTGTTGCTGCTCTATTTGATGATCAGCGAATTGTATCTGAAAAAGGC
AAGTTCAATGCTTAACTGGGCATATTCCATGCTCAGCCAGCTTTATATAGGCCTGCCGTTTGCCTTGCTTAATGTCTTGG
CGTTTCATACTGATCCGGAATATAGCAGCGTAAGCTACAATCCGATTCTGCCATTGTCCATCTTTATATTCCTTTGGCTG
AGTGATACAGGTGCATATTGCGTCGGTTCATTAATTGGCAAACACCGCTTGTTTGAACGTATCTCTCCTAAAAAATCATG
GGAAGGTTCCATCGGCGGCGGAGTAGTAGCTATCGGAGCTTCTTTTGTCTTGGCACATTACTTCACGATTATGTCGATGT
GGGAATGGGCAGGTCTCGCTTTAGTCGTTGTCGTTTTCGGAACATGGGGCGACCTGACAGAATCATTACTGAAACGCCAG
CTGCACGTTAAAGATTCAGGGACCATTCTTCCGGGACACGGAGGGATGCTCGACCGTTTCGACAGTGCTTTGATGGCTAT
ACCGGCAGCAGTCTTTTATCTGTATGCACTAACTTGGTTTTAA

Upstream 100 bases:

>100_bases
GAAGGAAAAAAAGTAACCGTAGAAGGAAAAGTTACTATAGAAGCAAAATCCAATGAGAAAGAACAAACTACCGAATCTAA
ATAATTAAAACACGAAGATT

Downstream 100 bases:

>100_bases
TAACAGAATAAATAAAATAAAAGGTCGGAAGCCGCTTTGAAGCACTTCCGACCTTTTTTTTTCACACACAGTGTTCGTCA
AGGTTTAGGTTTAGTTATTT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MISNFIKRAITGILFVAILVGCILYNSFSFGILFMAISALTIYEFGQLINSRAEGVNVNKTIIMLGGAYLFLAVMGFCID
AADSKIFIPYLLLLLYLMISELYLKKASSMLNWAYSMLSQLYIGLPFALLNVLAFHTDPEYSSVSYNPILPLSIFIFLWL
SDTGAYCVGSLIGKHRLFERISPKKSWEGSIGGGVVAIGASFVLAHYFTIMSMWEWAGLALVVVVFGTWGDLTESLLKRQ
LHVKDSGTILPGHGGMLDRFDSALMAIPAAVFYLYALTWF

Sequences:

>Translated_280_residues
MISNFIKRAITGILFVAILVGCILYNSFSFGILFMAISALTIYEFGQLINSRAEGVNVNKTIIMLGGAYLFLAVMGFCID
AADSKIFIPYLLLLLYLMISELYLKKASSMLNWAYSMLSQLYIGLPFALLNVLAFHTDPEYSSVSYNPILPLSIFIFLWL
SDTGAYCVGSLIGKHRLFERISPKKSWEGSIGGGVVAIGASFVLAHYFTIMSMWEWAGLALVVVVFGTWGDLTESLLKRQ
LHVKDSGTILPGHGGMLDRFDSALMAIPAAVFYLYALTWF
>Mature_280_residues
MISNFIKRAITGILFVAILVGCILYNSFSFGILFMAISALTIYEFGQLINSRAEGVNVNKTIIMLGGAYLFLAVMGFCID
AADSKIFIPYLLLLLYLMISELYLKKASSMLNWAYSMLSQLYIGLPFALLNVLAFHTDPEYSSVSYNPILPLSIFIFLWL
SDTGAYCVGSLIGKHRLFERISPKKSWEGSIGGGVVAIGASFVLAHYFTIMSMWEWAGLALVVVVFGTWGDLTESLLKRQ
LHVKDSGTILPGHGGMLDRFDSALMAIPAAVFYLYALTWF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=156, Percent_Identity=37.1794871794872, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787677, Length=114, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30991; Mature: 30991

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNFIKRAITGILFVAILVGCILYNSFSFGILFMAISALTIYEFGQLINSRAEGVNVNK
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TIIMLGGAYLFLAVMGFCIDAADSKIFIPYLLLLLYLMISELYLKKASSMLNWAYSMLSQ
EEEEECHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYIGLPFALLNVLAFHTDPEYSSVSYNPILPLSIFIFLWLSDTGAYCVGSLIGKHRLFER
HHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ISPKKSWEGSIGGGVVAIGASFVLAHYFTIMSMWEWAGLALVVVVFGTWGDLTESLLKRQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LHVKDSGTILPGHGGMLDRFDSALMAIPAAVFYLYALTWF
HCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISNFIKRAITGILFVAILVGCILYNSFSFGILFMAISALTIYEFGQLINSRAEGVNVNK
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TIIMLGGAYLFLAVMGFCIDAADSKIFIPYLLLLLYLMISELYLKKASSMLNWAYSMLSQ
EEEEECHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYIGLPFALLNVLAFHTDPEYSSVSYNPILPLSIFIFLWLSDTGAYCVGSLIGKHRLFER
HHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ISPKKSWEGSIGGGVVAIGASFVLAHYFTIMSMWEWAGLALVVVVFGTWGDLTESLLKRQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LHVKDSGTILPGHGGMLDRFDSALMAIPAAVFYLYALTWF
HCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]