Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 29349383

GI number: 29349383

Start: 5175851

End: 5176912

Strand: Reverse

Name: aroB [H]

Synonym: BT_3975

Alternate gene names: 29349383

Gene position: 5176912-5175851 (Counterclockwise)

Preceding gene: 29349387

Following gene: 29349381

Centisome position: 82.69

GC content: 46.52

Gene sequence:

>1062_bases
ATGAGTAAACAAGAAGTCATTCTCTGCGAAAGCTTGGAAACAAGCCTCGGTCGTGCCATTGAAAGGTGTCCGCATGACAA
GTTATTCATCCTCACAGACGAACATACCCAGCGTCTTTGTCTGCCCTCATTGAAAGAGGTATCGTTTCTGAAAGACGCAG
TCGAAATCTGTATCGGAGCCGAAGATGTGCATAAGACACTGGAGACTCTGGCCTCCGTATGGATGGCACTGAGTCAGCAA
GGGGCTACACGTCACTCATTGCTCATCAACCTTGGTGGGGGCATGGTAACAGATTTGGGAGGCTTTGCCGCCGCTACCTT
CAAACGGGGGATTTCTTATATCAATATACCCACTACACTGTTGGCTATGGTCGACGCATCCGTCGGCGGTAAGACAGGTA
TCAACTTCAACGGACTGAAAAACGAGATAGGCTCGTTTGCTCCGGCAGACAGTGTGCTGATTGAAACTGAATTCCTGCGC
AGCCTCGATGCACAGAATTTCTTCTCCGGTTATGCTGAAATGTTAAAGCACGGATTAATCAGCAATACCGCACACTGGGT
CGAATTACTGGATTTCAATACCAATAACATTGATTATGCATATCTCAAAAATATGGTGGGACGATCGGTACAGGTGAAGG
AAGACATTGTGGAGCAAGACCCCTTCGAGCATGGCATCCGTAAAGCACTGAACCTGGGACATACAGCAGGACATGCCTTC
GAAAGTCTGGCATTGGCTGAGAATCGCCCCGTGCTGCATGGCTATGCCGTAGCATGGGGAATCGTATGCGAGCTTTACCT
GTCACACCTCAAAGTCGGCTTTCCGAAAGACAAGATGCGACAGACCATCCAATTCATCAAAGAGAATTATGGTTCATTCG
CATTCGACTGTAAGCAGTACGAACAACTCTACGCATTTATGCAACATGATAAGAAAAATACCTCAGGAACGGTCAATTTT
ACTTTACTGAAAGAGATCGGAGATATTTGCATCAACCAGACAGCTGATAAAGACACAATTTTTGAAATGCTTGACTTCTA
TCGCGAATGTATGGGAGTCTGA

Upstream 100 bases:

>100_bases
ACAGGAAACAATGCTTTCATAATTGAACGTTTTAACGAGACAAAAGTAAGTAAAAAAAGATATTTTATATACATTTGCAC
CAAGAAAAAGCAAAAGAATC

Downstream 100 bases:

>100_bases
TCTTGAAACTTATTATAATAATGAAGGAGAATGGGATTCCCTAAAAGGTTTCCCATTTCTTCTTTCCCTTTCCCATTCTC
CTCTCCCCACATATGCCTTT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSKQEVILCESLETSLGRAIERCPHDKLFILTDEHTQRLCLPSLKEVSFLKDAVEICIGAEDVHKTLETLASVWMALSQQ
GATRHSLLINLGGGMVTDLGGFAAATFKRGISYINIPTTLLAMVDASVGGKTGINFNGLKNEIGSFAPADSVLIETEFLR
SLDAQNFFSGYAEMLKHGLISNTAHWVELLDFNTNNIDYAYLKNMVGRSVQVKEDIVEQDPFEHGIRKALNLGHTAGHAF
ESLALAENRPVLHGYAVAWGIVCELYLSHLKVGFPKDKMRQTIQFIKENYGSFAFDCKQYEQLYAFMQHDKKNTSGTVNF
TLLKEIGDICINQTADKDTIFEMLDFYRECMGV

Sequences:

>Translated_353_residues
MSKQEVILCESLETSLGRAIERCPHDKLFILTDEHTQRLCLPSLKEVSFLKDAVEICIGAEDVHKTLETLASVWMALSQQ
GATRHSLLINLGGGMVTDLGGFAAATFKRGISYINIPTTLLAMVDASVGGKTGINFNGLKNEIGSFAPADSVLIETEFLR
SLDAQNFFSGYAEMLKHGLISNTAHWVELLDFNTNNIDYAYLKNMVGRSVQVKEDIVEQDPFEHGIRKALNLGHTAGHAF
ESLALAENRPVLHGYAVAWGIVCELYLSHLKVGFPKDKMRQTIQFIKENYGSFAFDCKQYEQLYAFMQHDKKNTSGTVNF
TLLKEIGDICINQTADKDTIFEMLDFYRECMGV
>Mature_352_residues
SKQEVILCESLETSLGRAIERCPHDKLFILTDEHTQRLCLPSLKEVSFLKDAVEICIGAEDVHKTLETLASVWMALSQQG
ATRHSLLINLGGGMVTDLGGFAAATFKRGISYINIPTTLLAMVDASVGGKTGINFNGLKNEIGSFAPADSVLIETEFLRS
LDAQNFFSGYAEMLKHGLISNTAHWVELLDFNTNNIDYAYLKNMVGRSVQVKEDIVEQDPFEHGIRKALNLGHTAGHAFE
SLALAENRPVLHGYAVAWGIVCELYLSHLKVGFPKDKMRQTIQFIKENYGSFAFDCKQYEQLYAFMQHDKKNTSGTVNFT
LLKEIGDICINQTADKDTIFEMLDFYRECMGV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=181, Percent_Identity=41.4364640883978, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320332, Length=381, Percent_Identity=29.9212598425197, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39368; Mature: 39236

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQEVILCESLETSLGRAIERCPHDKLFILTDEHTQRLCLPSLKEVSFLKDAVEICIGA
CCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCH
EDVHKTLETLASVWMALSQQGATRHSLLINLGGGMVTDLGGFAAATFKRGISYINIPTTL
HHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCEEEHHHHH
LAMVDASVGGKTGINFNGLKNEIGSFAPADSVLIETEFLRSLDAQNFFSGYAEMLKHGLI
HHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
SNTAHWVELLDFNTNNIDYAYLKNMVGRSVQVKEDIVEQDPFEHGIRKALNLGHTAGHAF
CCHHHHHHHEECCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHH
ESLALAENRPVLHGYAVAWGIVCELYLSHLKVGFPKDKMRQTIQFIKENYGSFAFDCKQY
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
EQLYAFMQHDKKNTSGTVNFTLLKEIGDICINQTADKDTIFEMLDFYRECMGV
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKQEVILCESLETSLGRAIERCPHDKLFILTDEHTQRLCLPSLKEVSFLKDAVEICIGA
CCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCH
EDVHKTLETLASVWMALSQQGATRHSLLINLGGGMVTDLGGFAAATFKRGISYINIPTTL
HHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCEEEHHHHH
LAMVDASVGGKTGINFNGLKNEIGSFAPADSVLIETEFLRSLDAQNFFSGYAEMLKHGLI
HHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
SNTAHWVELLDFNTNNIDYAYLKNMVGRSVQVKEDIVEQDPFEHGIRKALNLGHTAGHAF
CCHHHHHHHEECCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHH
ESLALAENRPVLHGYAVAWGIVCELYLSHLKVGFPKDKMRQTIQFIKENYGSFAFDCKQY
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
EQLYAFMQHDKKNTSGTVNFTLLKEIGDICINQTADKDTIFEMLDFYRECMGV
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA