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The map label for this gene is emrK [H]

Identifier: 29346659

GI number: 29346659

Start: 1555729

End: 1556757

Strand: Reverse

Name: emrK [H]

Synonym: BT_1249

Alternate gene names: 29346659

Gene position: 1556757-1555729 (Counterclockwise)

Preceding gene: 29346660

Following gene: 29346658

Centisome position: 24.87

GC content: 45.09

Gene sequence:

>1029_bases
ATGAGAGCTCGCAACATCATATTAAATATGGTGTGTGTATGTTTGGCTGTCTCCGGGCTCTGGTGGACTATTACTTATTT
TTGGCGTTACATTAACTACGAAGTGACCAATGATGCTTTTGTAGACCAATACGTTGCTCCGTTAAATATACGTGCTTCGG
GATATATCAAGGATATCCGTTTCAAGGAACATCAATATGTGCGTCAGGGAGATACCTTGTTAGTGCTCGATAACCGTGAA
TATCAAATTAAAGTGAAGGAAGCCGAAGCAGCTCTGCTGGATGCGCACGGTTTGCAGGATGTTCTTCACTCAGGTATCGA
AACTTCCCATACTAATATAGCCGTGCAGGATGCCAATATAGCCGAAGCGAAGGCGAAGCTCTGGCAATTGGAACAGGACT
ATCATCGCTTTGAACGTTTGCTGAAAGAAGAATCGGTGCCGGAACAACAGTACGAGCAGACCAAAGCCGCGTATGAAGCA
GCTGAGGCACGCTATCAGGCATTAGTCGCACAAAAACAGGCTGCTTTGTCGCAATATGCGGAAACGAGTAAAAAGACAAC
CGGAGTTCAAGCCGGTATCTTGCGTAAAGAAGCGGATTTGGATTTGGCTAAATTGAACTTGTCTTATACGGTACTCACTG
CTCCATACGATGGATATATGGGCAGGCGCACCTTAGAACCCGGACAGTATGTCCAGACGGGGCAAACCATCTCTTATCTG
GTACGCAACAAGGATAAATGGATTACTGCTAATTATAAGGAAACACAGATTGCCAATATCTATATTGGTCAGCAGGTACG
TGTTAAAGTAGATGCGTTGCCCGGGAAGATTTTTAACGGGGAAGTCACTGCTATCTCGGAGGCAACCGGGTCGAAATATT
CTCTGGTTCCCACAGACAATTCCGCGGGAAACTTTGTAAAAGTACAACAGCGTATCCCGGTACGGATAGAACTGGAGAAT
ATCTCTTCAGAAGAAATGGCACAATTAAGAGCGGGTATGATGGTTGAAACAGAAGCTTTGCGCAAATGA

Upstream 100 bases:

>100_bases
TGTGATTTATACTTATTATCAACTTCAGAAGGCTTGTGGTCGTCTATAATATATTAGGGTTATGGCAACATTAAAGGAAA
AAAAACGGAAACTTAAAAAA

Downstream 100 bases:

>100_bases
TAACAATGAAAGAGTTGGGAGTACCCGTTCGTTCCTGGGTGCCCGATTGGTTGGGGTTCTGTTGCATTTTCATTGTTATT
CTTCCGGTTACCATGCTGAA

Product: putative multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRARNIILNMVCVCLAVSGLWWTITYFWRYINYEVTNDAFVDQYVAPLNIRASGYIKDIRFKEHQYVRQGDTLLVLDNRE
YQIKVKEAEAALLDAHGLQDVLHSGIETSHTNIAVQDANIAEAKAKLWQLEQDYHRFERLLKEESVPEQQYEQTKAAYEA
AEARYQALVAQKQAALSQYAETSKKTTGVQAGILRKEADLDLAKLNLSYTVLTAPYDGYMGRRTLEPGQYVQTGQTISYL
VRNKDKWITANYKETQIANIYIGQQVRVKVDALPGKIFNGEVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIELEN
ISSEEMAQLRAGMMVETEALRK

Sequences:

>Translated_342_residues
MRARNIILNMVCVCLAVSGLWWTITYFWRYINYEVTNDAFVDQYVAPLNIRASGYIKDIRFKEHQYVRQGDTLLVLDNRE
YQIKVKEAEAALLDAHGLQDVLHSGIETSHTNIAVQDANIAEAKAKLWQLEQDYHRFERLLKEESVPEQQYEQTKAAYEA
AEARYQALVAQKQAALSQYAETSKKTTGVQAGILRKEADLDLAKLNLSYTVLTAPYDGYMGRRTLEPGQYVQTGQTISYL
VRNKDKWITANYKETQIANIYIGQQVRVKVDALPGKIFNGEVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIELEN
ISSEEMAQLRAGMMVETEALRK
>Mature_342_residues
MRARNIILNMVCVCLAVSGLWWTITYFWRYINYEVTNDAFVDQYVAPLNIRASGYIKDIRFKEHQYVRQGDTLLVLDNRE
YQIKVKEAEAALLDAHGLQDVLHSGIETSHTNIAVQDANIAEAKAKLWQLEQDYHRFERLLKEESVPEQQYEQTKAAYEA
AEARYQALVAQKQAALSQYAETSKKTTGVQAGILRKEADLDLAKLNLSYTVLTAPYDGYMGRRTLEPGQYVQTGQTISYL
VRNKDKWITANYKETQIANIYIGQQVRVKVDALPGKIFNGEVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIELEN
ISSEEMAQLRAGMMVETEALRK

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=292, Percent_Identity=30.8219178082192, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789041, Length=329, Percent_Identity=28.8753799392097, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790519, Length=314, Percent_Identity=28.0254777070064, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790012, Length=282, Percent_Identity=25.886524822695, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790024, Length=276, Percent_Identity=24.6376811594203, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1789900, Length=313, Percent_Identity=23.0031948881789, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1787013, Length=248, Percent_Identity=25.4032258064516, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38847; Mature: 38847

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARNIILNMVCVCLAVSGLWWTITYFWRYINYEVTNDAFVDQYVAPLNIRASGYIKDIR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHCCCEEEECCCCEEECE
FKEHQYVRQGDTLLVLDNREYQIKVKEAEAALLDAHGLQDVLHSGIETSHTNIAVQDANI
EHHHHHHHCCCEEEEECCCCEEEEEECHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCH
AEAKAKLWQLEQDYHRFERLLKEESVPEQQYEQTKAAYEAAEARYQALVAQKQAALSQYA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETSKKTTGVQAGILRKEADLDLAKLNLSYTVLTAPYDGYMGRRTLEPGQYVQTGQTISYL
HHHHHCCCCHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHCCCHHHHH
VRNKDKWITANYKETQIANIYIGQQVRVKVDALPGKIFNGEVTAISEATGSKYSLVPTDN
HCCCCCEEECCCCCCEEEEEEECCEEEEEEECCCCEEECCCEEEEECCCCCEEEEEECCC
SAGNFVKVQQRIPVRIELENISSEEMAQLRAGMMVETEALRK
CCCCEEEEEECCCEEEEECCCCHHHHHHHHCCCEEEHHHHCC
>Mature Secondary Structure
MRARNIILNMVCVCLAVSGLWWTITYFWRYINYEVTNDAFVDQYVAPLNIRASGYIKDIR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHCCCEEEECCCCEEECE
FKEHQYVRQGDTLLVLDNREYQIKVKEAEAALLDAHGLQDVLHSGIETSHTNIAVQDANI
EHHHHHHHCCCEEEEECCCCEEEEEECHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCH
AEAKAKLWQLEQDYHRFERLLKEESVPEQQYEQTKAAYEAAEARYQALVAQKQAALSQYA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETSKKTTGVQAGILRKEADLDLAKLNLSYTVLTAPYDGYMGRRTLEPGQYVQTGQTISYL
HHHHHCCCCHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHCCCHHHHH
VRNKDKWITANYKETQIANIYIGQQVRVKVDALPGKIFNGEVTAISEATGSKYSLVPTDN
HCCCCCEEECCCCCCEEEEEEECCEEEEEEECCCCEEECCCEEEEECCCCCEEEEEECCC
SAGNFVKVQQRIPVRIELENISSEEMAQLRAGMMVETEALRK
CCCCEEEEEECCCEEEEECCCCHHHHHHHHCCCEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]