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The map label for this gene is pgl [H]

Identifier: 29346630

GI number: 29346630

Start: 1517499

End: 1518188

Strand: Reverse

Name: pgl [H]

Synonym: BT_1220

Alternate gene names: 29346630

Gene position: 1518188-1517499 (Counterclockwise)

Preceding gene: 29346631

Following gene: 29346629

Centisome position: 24.25

GC content: 49.71

Gene sequence:

>690_bases
ATGGAGACAGCCCGTTCGTTGATATTCCACCTGGTGGATATCATGAATGCTGAACCGGACAAAACGTTCAACATAGCAGT
GAGTGGTGGCAGCACTCCCGCCTTGATGTTTGATTTATGGGCAAATGAATACGCTGATATTACTCCTTGGAAGCGTATGA
AACTTTATTGGGTAGACGAACGTTGCGTTCCTCCCGAAGATTCTGATAGTAATTATGGAATGATGCGTTCCCTGCTTTTG
GGGATAGTGCCCATTCCTTACGAAAATGTATTCCGCATCCGCGGAGAAGTGAAACCGGCAAAAGAAGCGGTCCGCTATTC
CGAACTTGTCAGCCAGCAGGTACCCAAGAAAAATGGCTGGCCCGAATTTGACATTGTGCTGTTGGGAGCGGGAGATGACG
GACATACTTCCTCTATCTTCCCCGGACAGGAGGCTTTGCTCTCTTCCGACCAGATTTATGTGACCAGCACTCATCCCCGC
AACGGACAGAAACGTATTGCAATGACCGGATTTCCGATCTTGACCGCTCGCCTTGTTATTTTTCTGATTACCGGAAAGGC
GAAGGCGGAAGTGGTGGAAGAAATTTGCCACTCGGGAGATACGGGGCCGGCGGCTTATATAGCGCATCATGCGGAGAATG
TCGAACTCTTTATGGATGCCGGAGCCGCGATGTATGTGCGGAATGACTGA

Upstream 100 bases:

>100_bases
TGATGCACGAGCATGGGGCAGACTGGACCAATCCGTGTAAGAATTTAACAAATACAGACCAATATTGCGAACTATGAAAC
TATCTGTTTTCCCGTCGTCT

Downstream 100 bases:

>100_bases
AAAGAGAGAGACAATATAAAGACAAAGTATATTATATATAAGAAGAGAGAGTAACATTGGAGAAGAGAGAAGCTCACGGG
GTCGAAGCCGGGAGCTTCTT

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
METARSLIFHLVDIMNAEPDKTFNIAVSGGSTPALMFDLWANEYADITPWKRMKLYWVDERCVPPEDSDSNYGMMRSLLL
GIVPIPYENVFRIRGEVKPAKEAVRYSELVSQQVPKKNGWPEFDIVLLGAGDDGHTSSIFPGQEALLSSDQIYVTSTHPR
NGQKRIAMTGFPILTARLVIFLITGKAKAEVVEEICHSGDTGPAAYIAHHAENVELFMDAGAAMYVRND

Sequences:

>Translated_229_residues
METARSLIFHLVDIMNAEPDKTFNIAVSGGSTPALMFDLWANEYADITPWKRMKLYWVDERCVPPEDSDSNYGMMRSLLL
GIVPIPYENVFRIRGEVKPAKEAVRYSELVSQQVPKKNGWPEFDIVLLGAGDDGHTSSIFPGQEALLSSDQIYVTSTHPR
NGQKRIAMTGFPILTARLVIFLITGKAKAEVVEEICHSGDTGPAAYIAHHAENVELFMDAGAAMYVRND
>Mature_229_residues
METARSLIFHLVDIMNAEPDKTFNIAVSGGSTPALMFDLWANEYADITPWKRMKLYWVDERCVPPEDSDSNYGMMRSLLL
GIVPIPYENVFRIRGEVKPAKEAVRYSELVSQQVPKKNGWPEFDIVLLGAGDDGHTSSIFPGQEALLSSDQIYVTSTHPR
NGQKRIAMTGFPILTARLVIFLITGKAKAEVVEEICHSGDTGPAAYIAHHAENVELFMDAGAAMYVRND

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=207, Percent_Identity=30.9178743961353, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI6912586, Length=211, Percent_Identity=32.7014218009479, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI115533058, Length=211, Percent_Identity=34.5971563981043, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533060, Length=211, Percent_Identity=34.5971563981043, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321687, Length=202, Percent_Identity=29.2079207920792, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321957, Length=187, Percent_Identity=33.6898395721925, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324362, Length=211, Percent_Identity=27.0142180094787, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319918, Length=214, Percent_Identity=26.6355140186916, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641119, Length=217, Percent_Identity=33.6405529953917, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25463; Mature: 25463

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METARSLIFHLVDIMNAEPDKTFNIAVSGGSTPALMFDLWANEYADITPWKRMKLYWVDE
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEECC
RCVPPEDSDSNYGMMRSLLLGIVPIPYENVFRIRGEVKPAKEAVRYSELVSQQVPKKNGW
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCC
PEFDIVLLGAGDDGHTSSIFPGQEALLSSDQIYVTSTHPRNGQKRIAMTGFPILTARLVI
CCEEEEEEECCCCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHH
FLITGKAKAEVVEEICHSGDTGPAAYIAHHAENVELFMDAGAAMYVRND
HEECCCHHHHHHHHHHHCCCCCCHHHEECCCCCEEEEEECCEEEEEECC
>Mature Secondary Structure
METARSLIFHLVDIMNAEPDKTFNIAVSGGSTPALMFDLWANEYADITPWKRMKLYWVDE
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEECC
RCVPPEDSDSNYGMMRSLLLGIVPIPYENVFRIRGEVKPAKEAVRYSELVSQQVPKKNGW
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCC
PEFDIVLLGAGDDGHTSSIFPGQEALLSSDQIYVTSTHPRNGQKRIAMTGFPILTARLVI
CCEEEEEEECCCCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHH
FLITGKAKAEVVEEICHSGDTGPAAYIAHHAENVELFMDAGAAMYVRND
HEECCCHHHHHHHHHHHCCCCCCHHHEECCCCCEEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]