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The map label for this gene is sasA [H]

Identifier: 29346468

GI number: 29346468

Start: 1344660

End: 1345793

Strand: Reverse

Name: sasA [H]

Synonym: BT_1058

Alternate gene names: 29346468

Gene position: 1345793-1344660 (Counterclockwise)

Preceding gene: 29346469

Following gene: 29346462

Centisome position: 21.5

GC content: 42.24

Gene sequence:

>1134_bases
ATGAATGTGGAAATTAATCCTTCCGAATATAAGGTCCTTATTGTGGACGACGTAATTTCAAATGTCCTTCTGCTGAAGGT
GCTTCTGACCAATGAGAAGTTCAATATTGTAACAGCAGGCAATGGAACTCAGGCTTTGGAGCAGGTGAAGAAAGAAAAAC
CTGATCTTGTGTTGCTGGATGTGATGATGCCGGATATCAGCGGTTTCGAAGTAGCCCAGCAAATGAAGGCCGATGAAGAA
ATGAGCGAAATTCCAGTGATCTTTCTTACTGCTTTGAATAGTACGGCGGATATCGTGAAAGGATTTCAGGTGGGCGGTAA
CGATTTTATTTCCAAACCGTTTAATAAAGAGGAACTGATTATTCGTGTAACGCATCAGATCTCGTTGGTGGCAGCCAAAC
GAATTATCATAGCACAAACAGAAGAGTTGCGCAAGACTATCATAGGACGTGATAAACTCTACTCTGTGATTGCACACGAC
CTGCGTTCGCCTATGGGCTCTATTAAGATGGTGCTCAATATGCTGATTCTGAACTTACCGAGTGAAACTATCGGCTCTGA
AATGTATGAACTGCTGACAATGGCCAATCAGACAACAGAGGATGTATTTTCCTTACTCGACAACTTATTGAAGTGGACGA
AGAGTCAGATTGGTAAGCTGAAAGTTGTTTACCAGAATATCGATATGGTAGAAGTAGTGGAAGGAGTGAGCGAGATCTTT
ACAATGGTAGCCGGGCTGAAGAATATCCACATTGCTGTGGAAATACCTGAAGATCGTATGGAAGTACGTGCGGATATTGA
TATGATTAAGACAGTTATCCGTAACTTGATAAGTAATGCAATCAAGTTCAGTAACGAGGGATCGGAAGTCTTGGTATCAC
TGAGAGAAGAAGATAGCATGGCGATAGTTAGCGTGAAGGATAGCGGGTGTGGTATTGATGAAGAAAATCAGAAGAAATTG
TTGCATACCGATACGCATTTCAGTACTTTCGGTACAAATAATGAAGAAGGTTCAGGACTCGGACTGCTGCTCTGTAAGGA
CTTTGTTACTAAGAACGGAGGTGAGCTCTGGTTCACTTCGAAGAAAGGAGAAGGTTCTACGTTCAGTTTCTCGATTCCGT
TGTTGGAAAGCTAA

Upstream 100 bases:

>100_bases
AGAAACTGGGATGGCAGCCTACCGTCGAGCTGGAAGATGGGCTGAAGCGTATGATTGAGTATTTTAAAAATGTCTGATGT
AACATAAAAAATAGAATGAT

Downstream 100 bases:

>100_bases
TATAAGTTCGATATAAGATAAAAACCTGTCCTGTTTTCTAAGCACATTACTTTAGAGAAGTAGTGACAGCTCAGAATAAC
AGGACAGGTTTTGTTTGATA

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MNVEINPSEYKVLIVDDVISNVLLLKVLLTNEKFNIVTAGNGTQALEQVKKEKPDLVLLDVMMPDISGFEVAQQMKADEE
MSEIPVIFLTALNSTADIVKGFQVGGNDFISKPFNKEELIIRVTHQISLVAAKRIIIAQTEELRKTIIGRDKLYSVIAHD
LRSPMGSIKMVLNMLILNLPSETIGSEMYELLTMANQTTEDVFSLLDNLLKWTKSQIGKLKVVYQNIDMVEVVEGVSEIF
TMVAGLKNIHIAVEIPEDRMEVRADIDMIKTVIRNLISNAIKFSNEGSEVLVSLREEDSMAIVSVKDSGCGIDEENQKKL
LHTDTHFSTFGTNNEEGSGLGLLLCKDFVTKNGGELWFTSKKGEGSTFSFSIPLLES

Sequences:

>Translated_377_residues
MNVEINPSEYKVLIVDDVISNVLLLKVLLTNEKFNIVTAGNGTQALEQVKKEKPDLVLLDVMMPDISGFEVAQQMKADEE
MSEIPVIFLTALNSTADIVKGFQVGGNDFISKPFNKEELIIRVTHQISLVAAKRIIIAQTEELRKTIIGRDKLYSVIAHD
LRSPMGSIKMVLNMLILNLPSETIGSEMYELLTMANQTTEDVFSLLDNLLKWTKSQIGKLKVVYQNIDMVEVVEGVSEIF
TMVAGLKNIHIAVEIPEDRMEVRADIDMIKTVIRNLISNAIKFSNEGSEVLVSLREEDSMAIVSVKDSGCGIDEENQKKL
LHTDTHFSTFGTNNEEGSGLGLLLCKDFVTKNGGELWFTSKKGEGSTFSFSIPLLES
>Mature_377_residues
MNVEINPSEYKVLIVDDVISNVLLLKVLLTNEKFNIVTAGNGTQALEQVKKEKPDLVLLDVMMPDISGFEVAQQMKADEE
MSEIPVIFLTALNSTADIVKGFQVGGNDFISKPFNKEELIIRVTHQISLVAAKRIIIAQTEELRKTIIGRDKLYSVIAHD
LRSPMGSIKMVLNMLILNLPSETIGSEMYELLTMANQTTEDVFSLLDNLLKWTKSQIGKLKVVYQNIDMVEVVEGVSEIF
TMVAGLKNIHIAVEIPEDRMEVRADIDMIKTVIRNLISNAIKFSNEGSEVLVSLREEDSMAIVSVKDSGCGIDEENQKKL
LHTDTHFSTFGTNNEEGSGLGLLLCKDFVTKNGGELWFTSKKGEGSTFSFSIPLLES

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=28.3898305084746, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=25.7383966244726, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786599, Length=132, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=27.0742358078603, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=25, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=221, Percent_Identity=26.2443438914027, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790860, Length=112, Percent_Identity=35.7142857142857, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=236, Percent_Identity=25.4237288135593, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789809, Length=114, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=27.2340425531915, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786600, Length=277, Percent_Identity=27.0758122743682, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786912, Length=279, Percent_Identity=25.089605734767, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.037037037037, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=227, Percent_Identity=24.2290748898678, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=22.6086956521739, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI2367329, Length=113, Percent_Identity=43.3628318584071, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788394, Length=132, Percent_Identity=28.7878787878788, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=30.952380952381, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786784, Length=122, Percent_Identity=31.9672131147541, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=21.1453744493392, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=32.4786324786325, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 41876; Mature: 41876

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVEINPSEYKVLIVDDVISNVLLLKVLLTNEKFNIVTAGNGTQALEQVKKEKPDLVLLD
CCCEECCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
VMMPDISGFEVAQQMKADEEMSEIPVIFLTALNSTADIVKGFQVGGNDFISKPFNKEELI
EECCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCHHHCCCCCCCCEE
IRVTHQISLVAAKRIIIAQTEELRKTIIGRDKLYSVIAHDLRSPMGSIKMVLNMLILNLP
EEEEHHHHHHHHHHHHEECHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SETIGSEMYELLTMANQTTEDVFSLLDNLLKWTKSQIGKLKVVYQNIDMVEVVEGVSEIF
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHH
TMVAGLKNIHIAVEIPEDRMEVRADIDMIKTVIRNLISNAIKFSNEGSEVLVSLREEDSM
HHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
AIVSVKDSGCGIDEENQKKLLHTDTHFSTFGTNNEEGSGLGLLLCKDFVTKNGGELWFTS
EEEEEECCCCCCCCCCCCCEEECCCCCEECCCCCCCCCCEEEEEEHHHHHCCCCEEEEEE
KKGEGSTFSFSIPLLES
CCCCCCEEEEECCCCCC
>Mature Secondary Structure
MNVEINPSEYKVLIVDDVISNVLLLKVLLTNEKFNIVTAGNGTQALEQVKKEKPDLVLLD
CCCEECCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
VMMPDISGFEVAQQMKADEEMSEIPVIFLTALNSTADIVKGFQVGGNDFISKPFNKEELI
EECCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCHHHCCCCCCCCEE
IRVTHQISLVAAKRIIIAQTEELRKTIIGRDKLYSVIAHDLRSPMGSIKMVLNMLILNLP
EEEEHHHHHHHHHHHHEECHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SETIGSEMYELLTMANQTTEDVFSLLDNLLKWTKSQIGKLKVVYQNIDMVEVVEGVSEIF
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHH
TMVAGLKNIHIAVEIPEDRMEVRADIDMIKTVIRNLISNAIKFSNEGSEVLVSLREEDSM
HHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
AIVSVKDSGCGIDEENQKKLLHTDTHFSTFGTNNEEGSGLGLLLCKDFVTKNGGELWFTS
EEEEEECCCCCCCCCCCCCEEECCCCCEECCCCCCCCCCEEEEEEHHHHHCCCCEEEEEE
KKGEGSTFSFSIPLLES
CCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA