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The map label for this gene is orn [H]

Identifier: 29144651

GI number: 29144651

Start: 4554281

End: 4554826

Strand: Direct

Name: orn [H]

Synonym: t4402

Alternate gene names: 29144651

Gene position: 4554281-4554826 (Clockwise)

Preceding gene: 29144647

Following gene: 29144654

Centisome position: 95.04

GC content: 54.21

Gene sequence:

>546_bases
ATGAGTGCCGATGAAAACAACCTGATTTGGATCGATCTGGAGATGACAGGTCTGGACCCCGAACGCGATCGCATTATTGA
GATAGCCACGCTAGTGACGGATGCCAGCCTGAACATTCTGGCGGAAGGGCCGACGATTGCGGTACATCAATCCGATGCGC
AACTGGCGTTAATGGATGACTGGAACGTGCGCACCCATACCGGTAGCGGCCTGGTAGATCGCGTTAAAGCAAGTACGATG
GGCGAACGAGACGCTGAACTGGCGACGATTGAATTTCTGAAAACGTGGGTGCCTGCGGGTAAGTCGCCGATTTGCGGTAA
CAGCATCGGTCAGGATCGTCGTTTTCTGTTTAAATATATGCCGGAACTGGAGGCTTACTTCCACTATCGCTATCTGGATG
TCAGTACGCTCAAGGAACTGGCGCGCCGCTGGAAGCCGGAGATTCTGGCCGGCTTTACCAAGCAGGGCACGCACCAGGCG
ATGGATGATATTCGCGAGTCGGTGGCGGAGCTGGCTTACTACCGCGAGCATTTCATTAAGCTGTGA

Upstream 100 bases:

>100_bases
TGGCTCCTGGTCGCCCATAGTGGGCAAAACATCTATGATACACGCAATTGTAGATGAATATAGTCACAGTGAATGTGACC
TCTGAAGGGTGGAAAATAGC

Downstream 100 bases:

>100_bases
GGCGTAACATGCCGGATGGCAACGCCAGAGCGTCTCATCCGGCAGCTCTCCCGCCACTGAATTACTGCGTAAACCATTTC
TCCTGCATTTGCGCATATTC

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSADENNLIWIDLEMTGLDPERDRIIEIATLVTDASLNILAEGPTIAVHQSDAQLALMDDWNVRTHTGSGLVDRVKASTM
GERDAELATIEFLKTWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILAGFTKQGTHQA
MDDIRESVAELAYYREHFIKL

Sequences:

>Translated_181_residues
MSADENNLIWIDLEMTGLDPERDRIIEIATLVTDASLNILAEGPTIAVHQSDAQLALMDDWNVRTHTGSGLVDRVKASTM
GERDAELATIEFLKTWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILAGFTKQGTHQA
MDDIRESVAELAYYREHFIKL
>Mature_180_residues
SADENNLIWIDLEMTGLDPERDRIIEIATLVTDASLNILAEGPTIAVHQSDAQLALMDDWNVRTHTGSGLVDRVKASTMG
ERDAELATIEFLKTWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILAGFTKQGTHQAM
DDIRESVAELAYYREHFIKL

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides [H]

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI224496106, Length=183, Percent_Identity=46.9945355191257, Blast_Score=175, Evalue=3e-44,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=94.475138121547, Blast_Score=359, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17557752, Length=177, Percent_Identity=49.7175141242938, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=182, Percent_Identity=34.6153846153846, Blast_Score=111, Evalue=8e-26,
Organism=Drosophila melanogaster, GI21355135, Length=177, Percent_Identity=44.0677966101695, Blast_Score=177, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20633; Mature: 20501

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADENNLIWIDLEMTGLDPERDRIIEIATLVTDASLNILAEGPTIAVHQSDAQLALMDD
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCEEEEEEC
WNVRTHTGSGLVDRVKASTMGERDAELATIEFLKTWVPAGKSPICGNSIGQDRRFLFKYM
CCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYLDVSTLKELARRWKPEILAGFTKQGTHQAMDDIRESVAELAYYREHFIK
HHHHHHHHHEEECHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
SADENNLIWIDLEMTGLDPERDRIIEIATLVTDASLNILAEGPTIAVHQSDAQLALMDD
CCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCEEEEEEC
WNVRTHTGSGLVDRVKASTMGERDAELATIEFLKTWVPAGKSPICGNSIGQDRRFLFKYM
CCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYLDVSTLKELARRWKPEILAGFTKQGTHQAMDDIRESVAELAYYREHFIK
HHHHHHHHHEEECHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA