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The map label for this gene is aroE [H]

Identifier: 29144368

GI number: 29144368

Start: 4240066

End: 4240884

Strand: Direct

Name: aroE [H]

Synonym: t4103

Alternate gene names: 29144368

Gene position: 4240066-4240884 (Clockwise)

Preceding gene: 29144367

Following gene: 29144369

Centisome position: 88.48

GC content: 50.31

Gene sequence:

>819_bases
ATGGAAGCCTATGCTGTTTTTGGAAATCCGATTGCGCACAGCAAATCGCCATTTATTCATCAGCAATTTGCTCAGCAGCT
AGATATTGTTCACCCCTATGGTCGCGTGCTGGCCCCCATTAATAATTTCATTAATACGCTTGATGCCTTTTTCGCGGCAG
GGGGAAAAGGCGCAAACATCACAGTACCTTTTAAAGAGGAGGCGTTTGCGCGTTCGGATGAGTTAACGGAACGAGCATCG
CTGGCGGGAGCCGTCAATACATTAAAACGGCTGGAAGATGGTCGTTTGCTTGGCGACAATACTGACGGTATCGGTTTATT
AAGCGATCTCGAACGTTTAAATTTTATCCGCCCAGGATTGCGTATTTTGCTGATTGGCGCGGGCGGCGCATCCCGGGGCG
TGCTGTTACCCCTGCTTTCTTTGGATTGTGCGGTCACTATCACTAACCGTACAGCTTCACGTGCCGAAGCGTTGGCGAAA
ATCTTTGCTCATACCGGCAGCGTTCATGCTATGGATATGGACAAGCTGGATGGTTGTGAGTTTGACCTGATTATTAATGC
GACCTCCAGCGGCATACGGGGCGAAATCCCGGCGATTCCGGCGTCACTTATTCATCCTTCCCTCTGTTGCTATGACATGT
TCTATCAAAAAGGGAATACGCCATTTCTCTCCTGGTGTGTACAACAGGGCGCGAAACGCTACGCAGATGGGCTGGGAATG
CTGGTGGGGCAGGCTGCACATGCCGTTTTGCTTTGGCACGGTGTATTACCGCAGGTCGAGCCAGTGATTAAGCTGCTACA
GCAGGAATTATTAGCGTGA

Upstream 100 bases:

>100_bases
GATGATTTTCCGGTGGTTGAAGGCGCAACGGGTGGGCGTTTAAATCCTTCAGAAATCCGCGATGCTCTGACGGGCGAACT
ATTTCGACAGGGGTAATATG

Downstream 100 bases:

>100_bases
ACCAGGCCATACAATTCCCTGACCGCGAAGAATGGGATACTGCCGCCAGCGCTATCATCTTTCCCGCCCTGGTCAATGGG
ATGCAAATCACGTGTGCGAT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MEAYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFINTLDAFFAAGGKGANITVPFKEEAFARSDELTERAS
LAGAVNTLKRLEDGRLLGDNTDGIGLLSDLERLNFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAK
IFAHTGSVHAMDMDKLDGCEFDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKGNTPFLSWCVQQGAKRYADGLGM
LVGQAAHAVLLWHGVLPQVEPVIKLLQQELLA

Sequences:

>Translated_272_residues
MEAYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFINTLDAFFAAGGKGANITVPFKEEAFARSDELTERAS
LAGAVNTLKRLEDGRLLGDNTDGIGLLSDLERLNFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAK
IFAHTGSVHAMDMDKLDGCEFDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKGNTPFLSWCVQQGAKRYADGLGM
LVGQAAHAVLLWHGVLPQVEPVIKLLQQELLA
>Mature_272_residues
MEAYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFINTLDAFFAAGGKGANITVPFKEEAFARSDELTERAS
LAGAVNTLKRLEDGRLLGDNTDGIGLLSDLERLNFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAK
IFAHTGSVHAMDMDKLDGCEFDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKGNTPFLSWCVQQGAKRYADGLGM
LVGQAAHAVLLWHGVLPQVEPVIKLLQQELLA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=272, Percent_Identity=85.2941176470588, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1787983, Length=287, Percent_Identity=27.8745644599303, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320332, Length=163, Percent_Identity=35.5828220858896, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29304; Mature: 29304

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFINTLDAFFAAGGKGANI
CCCEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TVPFKEEAFARSDELTERASLAGAVNTLKRLEDGRLLGDNTDGIGLLSDLERLNFIRPGL
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHCCCE
RILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAKIFAHTGSVHAMDMDKLDGCE
EEEEEECCCCCCCHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCCCEEEECCHHCCCCC
FDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKGNTPFLSWCVQQGAKRYADGLGM
EEEEEECCCCCCCCCCCCCCHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LVGQAAHAVLLWHGVLPQVEPVIKLLQQELLA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEAYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFINTLDAFFAAGGKGANI
CCCEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TVPFKEEAFARSDELTERASLAGAVNTLKRLEDGRLLGDNTDGIGLLSDLERLNFIRPGL
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHCCCE
RILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAKIFAHTGSVHAMDMDKLDGCE
EEEEEECCCCCCCHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCCCEEEECCHHCCCCC
FDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKGNTPFLSWCVQQGAKRYADGLGM
EEEEEECCCCCCCCCCCCCCHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LVGQAAHAVLLWHGVLPQVEPVIKLLQQELLA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA