Click here to switch to the map view.

The map label for this gene is yheR [H]

Identifier: 29144312

GI number: 29144312

Start: 4204585

End: 4205136

Strand: Direct

Name: yheR [H]

Synonym: t4047

Alternate gene names: 29144312

Gene position: 4204585-4205136 (Clockwise)

Preceding gene: 29144310

Following gene: 29144313

Centisome position: 87.74

GC content: 55.07

Gene sequence:

>552_bases
ATGTCTCAGCCAGCGAAAGTCTTGCTGTTGTATGCCCATCCGGAATCTCAGGACTCGGTTGCTAACCGGGTACTGCTTAA
ACCGGCCATACAGCACAATAACGTAACCGTGCACGATCTTTATGCGCGCTATCCTGATTTTTTTATCGATACGCCCTATG
AACAAGCCCTGTTACGTGAGCACGACGTCATTGTTTTTCAGCATCCCCTTTACACCTATAGCTGTCCGGCTTTACTGAAA
GAATGGCTTGATCGCGTTTTGAGTCGAGGGTTCGCCAGCGGACCAGGGGGAAACCAACTGGTGGGAAAGTACTGGCGTAG
CGTGATTACGACCGGCGAGCCGGAGAGCGCTTACCGGTATGACGCGCTAAACCGCTATCCAATGAGCGATGTACTCCGCC
CTTTTGAACTGACCGCGGCCATGTGCCGGATGCACTGGATGCCGCCCATTATTGTGTACTGGGCGCGCCGCCAGTCGCCG
CAGACGCTGGCCAGTCATGCGAAAGCCTATGGCGAGTGGCTGGCGAATCCTGTGAGCGCGGGAGGCTATTGA

Upstream 100 bases:

>100_bases
GCGGACATGGAGTACGTTTCTGAGTTGAACAAACGCTGTCAACGTAGAAGCGGCCTGAAGAATGGCATGTATCGACCCAA
AACAACCGGGAGGGGGATTG

Downstream 100 bases:

>100_bases
TGGAAGGTGCTGATTTATTGACCGCGGGAGTGTTGTTCCTCTTCGCGGCGGTAGCGGCGGTGCCGCTGGCCGCGAGGCTG
GGCATCGGCGCGGTGCTAGG

Product: glutathione-regulated potassium-efflux system ancillary protein KefG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLK
EWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSP
QTLASHAKAYGEWLANPVSAGGY

Sequences:

>Translated_183_residues
MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLK
EWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSP
QTLASHAKAYGEWLANPVSAGGY
>Mature_182_residues
SQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKE
WLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQ
TLASHAKAYGEWLANPVSAGGY

Specific function: Required for full activity of kefB [H]

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=158, Percent_Identity=33.5443037974684, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789750, Length=182, Percent_Identity=89.5604395604396, Blast_Score=343, Evalue=4e-96,
Organism=Escherichia coli, GI1786231, Length=167, Percent_Identity=40.1197604790419, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 20927; Mature: 20796

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLRE
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCCCCCHHHHHHHH
HDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRY
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHH
DALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQTLASHAKAYGEWLANPVSA
HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
GGY
CCC
>Mature Secondary Structure 
SQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLRE
CCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCCCCCHHHHHHHH
HDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRY
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHH
DALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQTLASHAKAYGEWLANPVSA
HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
GGY
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA