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The map label for this gene is nfuA [H]

Identifier: 29144263

GI number: 29144263

Start: 4145213

End: 4145788

Strand: Reverse

Name: nfuA [H]

Synonym: t3995

Alternate gene names: 29144263

Gene position: 4145788-4145213 (Counterclockwise)

Preceding gene: 29144264

Following gene: 29144262

Centisome position: 86.52

GC content: 53.65

Gene sequence:

>576_bases
ATGATCCGTATTTCCGATGCTGCACAAGCGCACTTTGCCAAACTGCTGGCAAATCAGAAAGAAGGGACGCAAATCCGCGT
ATTTGTCATTAATCCCGGCACTCCTAACGCAGAGTGCGGCGTTTCTTATTGTCCGCCCGACGCCGTAGAAGCCACCGATA
CTGCACTGAAATTTGACCTGTTGACCGCTTATGTCGACGAGCTGAGCGCGCCCTATCTGGAAGACGCGGAAATTGATTTC
GTGACCGACCAGCTAGGTTCTCAACTCACATTGAAAGCGCCAAACGCGAAGATGCGCAAAGTGGCCGATGACGCGCCGCT
GATGGAGCGCGTGGAATATGCTCTGCAATCGCAGATTAACCCGCAGTTGGCGGGCCACGGCGGTCGCGTCTCGCTGATGG
AAATTACCGATGAAGGCTATGCAATTCTGCAGTTTGGCGGCGGTTGTAACGGTTGCTCGATGGTTGACGTCACGCTGAAA
GAAGGGATCGAGAAACAGTTGCTGAATGAATTCCCGGAACTGAAAGGGGTTCGCGATCTGACCGAACACCAGCGCGGCGA
GCACTCATACTACTAA

Upstream 100 bases:

>100_bases
GCAGCGACTGTCCAGGTATGGTGCCTGTGTCGAACCTTGTAGAGCCTCGATGACGGGCGTATTATAACCAACTAAAATAG
TCAACTATTAGGCCATTACT

Downstream 100 bases:

>100_bases
GATTTTCCCCGCATCCATGCCCGATGGCGCTTGCGCCTGTCGGGCCTTGTCTGCCCCACCGTAGGCCGAATAAGGCGTCT
ACGCCGCCATTCTGCGCCAT

Product: DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MIRISDAAQAHFAKLLANQKEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDF
VTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLK
EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY

Sequences:

>Translated_191_residues
MIRISDAAQAHFAKLLANQKEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDF
VTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLK
EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
>Mature_191_residues
MIRISDAAQAHFAKLLANQKEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDF
VTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLK
EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins [H]

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family [H]

Homologues:

Organism=Escherichia coli, GI1789819, Length=191, Percent_Identity=97.9057591623037, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- ProDom:   PD002830 [H]

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU [H]

EC number: NA

Molecular weight: Translated: 20937; Mature: 20937

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRISDAAQAHFAKLLANQKEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDL
CEEECHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQIN
HHHHHHHHCCCCCCCCCEEEEHHHCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCC
PQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDL
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEHHHHHCHHHHHHHHHHHHCCHHHH
TEHQRGEHSYY
HHHHCCCCCCC
>Mature Secondary Structure
MIRISDAAQAHFAKLLANQKEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDL
CEEECHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQIN
HHHHHHHHCCCCCCCCCEEEEHHHCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCC
PQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDL
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEHHHHHCHHHHHHHHHHHHCCHHHH
TEHQRGEHSYY
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA