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The map label for this gene is dppC [H]

Identifier: 29144161

GI number: 29144161

Start: 4014617

End: 4015519

Strand: Direct

Name: dppC [H]

Synonym: t3887

Alternate gene names: 29144161

Gene position: 4014617-4015519 (Clockwise)

Preceding gene: 29144160

Following gene: 29144162

Centisome position: 83.78

GC content: 60.13

Gene sequence:

>903_bases
ATGTCACAGGTTACTGAAAATAATGTTAATGCCGCACCGGCGCCCATGACGCCATTGCGGGAGTTCTGGCACTATTTCAA
ACGCAATAAAGGCGCGGTCGTCGGGCTGGCGTATGTTCTCATCGTGATCCTGATTGCGGTGTTTGCCAACTTTATTGCGC
CGTACAACCCGGCAGAGCAGTTCCGCGATGCGCTGCTGGCGCCGCCGGTCTGGCAGGAAGGCGGCAGTTGGGCGCATATT
CTGGGAACGGATGATGTTGGTCGCGATGCCCTCTCGCGCCTGATGTATGGCGCGCGTTTGTCGCTGCTGGTCGGCTGTCT
GGTGGTCGTCCTGTCGCTGGTCATGGGGATTATTCTCGGCCTAGTCGCGGGCTACTTCGGCGGTCTGGTCGATAACATCA
TCATGCGCGTGGTCGATATTATGCTGGCCCTGCCGAGCCTGCTGCTGGCGCTGGTGCTGGTGGCGATCTTCGGCCCCTCC
ATCGGCAACGCTGCGCTGGCGTTGACGTTTGTGGCGCTGCCGCACTATGTCCGCTTAACCCGCGCGGCGGTTCTGGTAGA
GGTGAACCGCGATTATGTGACTGCCTCCCGCGTGGCGGGCGCAGGCGCGATGCGTCAGATGTTCGTCAATATTTTCCCGA
ACTGCCTTGCGCCGCTGATCGTTCAGGCATCGCTCGGTTTCTCTAACGCCATTCTCGATATGGCCGCCCTCGGCTTTCTT
GGCATGGGCGCGCAGCCGCCTACGCCGGAATGGGGCACCATGCTCTCTGATGTATTGCAGTTCGCGCAAAGCGCCTGGTG
GGTCGTGACCTTCCCGGGGCTGGCGATTCTGCTGACGGTACTGGCATTTAACCTGATGGGTGACGGTCTGCGTGACGCGC
TCGATCCCAAACTGAAGCAGTAA

Upstream 100 bases:

>100_bases
GTTACTGGTAGCGACGATGATTATTCTCGTCAACCTGCTGGTAGACCTGCTGTACGGCGTGGTGAACCCGCGTATTCGGC
ATAAGAAGTAAGGGGCCATC

Downstream 100 bases:

>100_bases
GAGGTTCGAGATGGCGTTATTAAATGTAGATCAATTATCGGTGCACTTCGGCGACGAAGGGACACCGTTCAAAGCCGTCG
ACCGCATTAGCTACAGCGTG

Product: dipeptide transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSQVTENNVNAAPAPMTPLREFWHYFKRNKGAVVGLAYVLIVILIAVFANFIAPYNPAEQFRDALLAPPVWQEGGSWAHI
LGTDDVGRDALSRLMYGARLSLLVGCLVVVLSLVMGIILGLVAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFVNIFPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ

Sequences:

>Translated_300_residues
MSQVTENNVNAAPAPMTPLREFWHYFKRNKGAVVGLAYVLIVILIAVFANFIAPYNPAEQFRDALLAPPVWQEGGSWAHI
LGTDDVGRDALSRLMYGARLSLLVGCLVVVLSLVMGIILGLVAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFVNIFPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ
>Mature_299_residues
SQVTENNVNAAPAPMTPLREFWHYFKRNKGAVVGLAYVLIVILIAVFANFIAPYNPAEQFRDALLAPPVWQEGGSWAHIL
GTDDVGRDALSRLMYGARLSLLVGCLVVVLSLVMGIILGLVAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSI
GNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFVNIFPNCLAPLIVQASLGFSNAILDMAALGFLG
MGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=300, Percent_Identity=93.6666666666667, Blast_Score=493, Evalue=1e-141,
Organism=Escherichia coli, GI1787054, Length=283, Percent_Identity=41.3427561837456, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI1787760, Length=259, Percent_Identity=45.1737451737452, Blast_Score=215, Evalue=2e-57,
Organism=Escherichia coli, GI1787549, Length=288, Percent_Identity=39.5833333333333, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789889, Length=249, Percent_Identity=38.9558232931727, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787498, Length=297, Percent_Identity=31.3131313131313, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=30.7339449541284, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32206; Mature: 32074

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVTENNVNAAPAPMTPLREFWHYFKRNKGAVVGLAYVLIVILIAVFANFIAPYNPAEQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
FRDALLAPPVWQEGGSWAHILGTDDVGRDALSRLMYGARLSLLVGCLVVVLSLVMGIILG
HHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RAAVLVEVNRDYVTASRVAGAGAMRQMFVNIFPNCLAPLIVQASLGFSNAILDMAALGFL
HHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SQVTENNVNAAPAPMTPLREFWHYFKRNKGAVVGLAYVLIVILIAVFANFIAPYNPAEQ
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
FRDALLAPPVWQEGGSWAHILGTDDVGRDALSRLMYGARLSLLVGCLVVVLSLVMGIILG
HHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RAAVLVEVNRDYVTASRVAGAGAMRQMFVNIFPNCLAPLIVQASLGFSNAILDMAALGFL
HHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]