Click here to switch to the map view.

The map label for this gene is uhpA [H]

Identifier: 29144019

GI number: 29144019

Start: 3843142

End: 3843732

Strand: Direct

Name: uhpA [H]

Synonym: t3728

Alternate gene names: 29144019

Gene position: 3843142-3843732 (Clockwise)

Preceding gene: 29144018

Following gene: 29144020

Centisome position: 80.2

GC content: 59.05

Gene sequence:

>591_bases
ATGATTACCGTTGCCCTTATCGACGACCACCTTATCGTCCGCTCCGGCTTTGCACAGCTACTGGGGCTGGAACCCGATTT
GCAGGTGGTCGCCGAGTTTGGTTCCGGGCGCGAAGCGTTGGCAGGCTTGCCGGGGCGCGGCGTACAGGTGTGTATCTGCG
ATATCTCGATGCCGGATATTTCCGGACTGGAGCTGCTAAGCCAACTGCCAAAAGGGATGGCGACGATCATGCTCTCGGTT
CACGATAGCCCGGCGCTGGTGGAACAGGCGTTGAACGCCGGCGCGCGCGGTTTTCTCTCTAAACGCTGTAGTCCGGATGA
GCTGATCGCCGCGGTGCATACGGTGGCGACGGGCGGCTGCTATTTGACCCCCGATATTGCCGTGAAACTGGCGGCGGGTC
GGCAAGATCCGCTGACCAAACGCGAGCGTCAGGTGGAGGAAAAACTCGCCCAGGGTATGGCGGTAAAAGAGATTGCCGCC
GAGCTGGGGCTGTCGCCAAAAATGGTGCATGTCCATCGCGCGAATCTGCTGGAAAAATTAGGCGTCAGCAATGACGTTGA
ACTGGCGCATCGCATGTTTGACGGTTGGTAA

Upstream 100 bases:

>100_bases
GGATGGCGGCATTAATGCCTTATCCGGCCTACAACGGCACCTGCCCGTAGGCCTGATAAGCGCAGCGCCATCAGGCATGT
CTTAGCGCCAGGATGAACCC

Downstream 100 bases:

>100_bases
TGAACACCTTTTTTTCCCGTTTAATCACCGTTGTTGCCTGCTTTTTTATCTTCTCCGCCGCGTGGTTCTGCCTGTGGAGC
ATCAGCCTGCATCTGGTAGA

Product: DNA-binding transcriptional activator UhpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAVKLAAGRQDPLTKRERQVEEKLAQGMAVKEIAA
ELGLSPKMVHVHRANLLEKLGVSNDVELAHRMFDGW

Sequences:

>Translated_196_residues
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAVKLAAGRQDPLTKRERQVEEKLAQGMAVKEIAA
ELGLSPKMVHVHRANLLEKLGVSNDVELAHRMFDGW
>Mature_196_residues
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAVKLAAGRQDPLTKRERQVEEKLAQGMAVKEIAA
ELGLSPKMVHVHRANLLEKLGVSNDVELAHRMFDGW

Specific function: Appears to be the positive activator of uhpT transcription [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=196, Percent_Identity=96.9387755102041, Blast_Score=386, Evalue=1e-109,
Organism=Escherichia coli, GI1788222, Length=202, Percent_Identity=36.1386138613861, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1788521, Length=194, Percent_Identity=36.0824742268041, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=33.879781420765, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786747, Length=196, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1788712, Length=183, Percent_Identity=27.3224043715847, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20911; Mature: 20911

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDI
CEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCCCCCCEEEEEECCCCCC
SGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGC
HHHHHHHHCCCCHHHEEEECCCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCE
YLTPDIAVKLAAGRQDPLTKRERQVEEKLAQGMAVKEIAAELGLSPKMVHVHRANLLEKL
EECHHHEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHHHHHH
GVSNDVELAHRMFDGW
CCCCHHHHHHHHHCCC
>Mature Secondary Structure
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDI
CEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCCCCCCEEEEEECCCCCC
SGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGC
HHHHHHHHCCCCHHHEEEECCCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCE
YLTPDIAVKLAAGRQDPLTKRERQVEEKLAQGMAVKEIAAELGLSPKMVHVHRANLLEKL
EECHHHEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHHHHHH
GVSNDVELAHRMFDGW
CCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]