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The map label for this gene is nanK [H]

Identifier: 29143587

GI number: 29143587

Start: 3344920

End: 3345795

Strand: Reverse

Name: nanK [H]

Synonym: t3253

Alternate gene names: 29143587

Gene position: 3345795-3344920 (Counterclockwise)

Preceding gene: 29143588

Following gene: 29143586

Centisome position: 69.82

GC content: 59.36

Gene sequence:

>876_bases
ATGACTACGTTAGCAATCGATATTGGCGGTACTAAACTTGCCGCCGCGCTCATCGACAACAACTTGCGCATTAGCCAGCG
TCGCGAGCTACCGACCCCCGCGAGCAAAACGCCGGATGCGTTACGTGAAGCATTAAAGGCGCTGGTTGAACCACTACGGG
CAGAGGCGCGTCAGGTAGCGATAGCTTCTACCGGGATCATTCAGGAAGGGATGCTGCTGGCGCTAAACCCCCATAATCTG
GGCGGCTTGCTACACTTTCCGTTAGTACAAACACTGGAAACGATCGCTGGCCTGCCGACGCTGGCGGTGAACGACGCGCA
GGCGGCGGCCTGGGCGGAGTATCACGCGCTCCCTGATGATATCCGCGATATGGTATTTATCACCGTTTCAACCGGCGTTG
GCGGCGGCGTTGTCTGCGACGGCAAGCTCCTTACCGGAAAAGGCGGTCTGGCCGGGCACCTGGGACACACCCTGGCGGAC
CCACACGGGCCCGTATGCGGCTGTGGACGCGTTGGTTGTGTAGAGGCCATCGCCTCCGGACGAGGGATGGCCGCGGCGGC
GCGGGACGATCTGGCGGGATGCGACGCCAAAACCCTATTTATTCGCGCTGGCGAAGGTCATCAGCAGGCGCGACATCTGG
TAAGCCAATCCGCGCAGGTAATAGCGCGAATGATCGCCGATGTGAAAGCGATTACCGACTGCCAGTGTGTGGTCATTGGC
GGCAGCGTAGGGTTAGCTGAGGGATACCTGGAGCAGGTTCGCGCGTTTTTGATGCAAGAGCCTGAGCCTTATCACGTGGC
GCTGAGCGCCGCTCGCTATCGGCATGACGCAGGATTATTAGGCGCTGCTTTGTTAGCTCAAGGAGACACATTATGA

Upstream 100 bases:

>100_bases
CGATCCGCTATGGCGCATGGGCGGTGACGGTGGGGTCCGCCATTACCCGTCTGGAACATATCTGTGGATGGTATAACGAC
GCATTAAAAAAGGCGGCGTC

Downstream 100 bases:

>100_bases
TGATGGGGGAAGTACAGTCGTTGCCTTCTTGCGGGTTGCATCCGCGACTGCTGGATGCCTTGACTCTCGCGCTGGCGGCA
AGGCCGCAGGAGAAAGCACC

Product: N-acetylmannosamine kinase

Products: NA

Alternate protein names: ManNAc kinase; N-acetyl-D-mannosamine kinase [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTTLAIDIGGTKLAAALIDNNLRISQRRELPTPASKTPDALREALKALVEPLRAEARQVAIASTGIIQEGMLLALNPHNL
GGLLHFPLVQTLETIAGLPTLAVNDAQAAAWAEYHALPDDIRDMVFITVSTGVGGGVVCDGKLLTGKGGLAGHLGHTLAD
PHGPVCGCGRVGCVEAIASGRGMAAAARDDLAGCDAKTLFIRAGEGHQQARHLVSQSAQVIARMIADVKAITDCQCVVIG
GSVGLAEGYLEQVRAFLMQEPEPYHVALSAARYRHDAGLLGAALLAQGDTL

Sequences:

>Translated_291_residues
MTTLAIDIGGTKLAAALIDNNLRISQRRELPTPASKTPDALREALKALVEPLRAEARQVAIASTGIIQEGMLLALNPHNL
GGLLHFPLVQTLETIAGLPTLAVNDAQAAAWAEYHALPDDIRDMVFITVSTGVGGGVVCDGKLLTGKGGLAGHLGHTLAD
PHGPVCGCGRVGCVEAIASGRGMAAAARDDLAGCDAKTLFIRAGEGHQQARHLVSQSAQVIARMIADVKAITDCQCVVIG
GSVGLAEGYLEQVRAFLMQEPEPYHVALSAARYRHDAGLLGAALLAQGDTL
>Mature_290_residues
TTLAIDIGGTKLAAALIDNNLRISQRRELPTPASKTPDALREALKALVEPLRAEARQVAIASTGIIQEGMLLALNPHNLG
GLLHFPLVQTLETIAGLPTLAVNDAQAAAWAEYHALPDDIRDMVFITVSTGVGGGVVCDGKLLTGKGGLAGHLGHTLADP
HGPVCGCGRVGCVEAIASGRGMAAAARDDLAGCDAKTLFIRAGEGHQQARHLVSQSAQVIARMIADVKAITDCQCVVIGG
SVGLAEGYLEQVRAFLMQEPEPYHVALSAARYRHDAGLLGAALLAQGDTL

Specific function: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NanK subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082230, Length=291, Percent_Identity=74.914089347079, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1787363, Length=302, Percent_Identity=30.4635761589404, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786891, Length=177, Percent_Identity=26.5536723163842, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082127, Length=97, Percent_Identity=35.0515463917526, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787878, Length=217, Percent_Identity=26.2672811059908, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.60 [H]

Molecular weight: Translated: 30178; Mature: 30047

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLAIDIGGTKLAAALIDNNLRISQRRELPTPASKTPDALREALKALVEPLRAEARQVA
CEEEEEECCCHHHHHHHHCCCCEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IASTGIIQEGMLLALNPHNLGGLLHFPLVQTLETIAGLPTLAVNDAQAAAWAEYHALPDD
HHHCCHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCHH
IRDMVFITVSTGVGGGVVCDGKLLTGKGGLAGHLGHTLADPHGPVCGCGRVGCVEAIASG
CCCEEEEEEECCCCCCEEECCEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHCC
RGMAAAARDDLAGCDAKTLFIRAGEGHQQARHLVSQSAQVIARMIADVKAITDCQCVVIG
CCCEEHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GSVGLAEGYLEQVRAFLMQEPEPYHVALSAARYRHDAGLLGAALLAQGDTL
CCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTLAIDIGGTKLAAALIDNNLRISQRRELPTPASKTPDALREALKALVEPLRAEARQVA
EEEEEECCCHHHHHHHHCCCCEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IASTGIIQEGMLLALNPHNLGGLLHFPLVQTLETIAGLPTLAVNDAQAAAWAEYHALPDD
HHHCCHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCHH
IRDMVFITVSTGVGGGVVCDGKLLTGKGGLAGHLGHTLADPHGPVCGCGRVGCVEAIASG
CCCEEEEEEECCCCCCEEECCEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHCC
RGMAAAARDDLAGCDAKTLFIRAGEGHQQARHLVSQSAQVIARMIADVKAITDCQCVVIG
CCCEEHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GSVGLAEGYLEQVRAFLMQEPEPYHVALSAARYRHDAGLLGAALLAQGDTL
CCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA