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The map label for this gene is uxaC [H]

Identifier: 29143402

GI number: 29143402

Start: 3140296

End: 3141708

Strand: Direct

Name: uxaC [H]

Synonym: t3058

Alternate gene names: 29143402

Gene position: 3140296-3141708 (Clockwise)

Preceding gene: 29143401

Following gene: 29143405

Centisome position: 65.53

GC content: 53.86

Gene sequence:

>1413_bases
ATGGCTACGTTTATGACTGAAGATTTTCTACTTAAAAACGACATTGCCCGCACGCTGTACCATAAATACGCCGCGCCCAT
GCCGATTTATGACTTCCACTGCCATTTAAGTCCGCAGGAAATCGCCGACGATCGCCGTTTCGATAACCTCGGTCAGATCT
GGCTGGAAGGCGACCACTATAAATGGCGAGCGCTACGAAGCGCAGGCGTGGATGAGTCGCTGATCACCGGCAAAGAGACC
AGCGATTATGAAAAATATATGGCCTGGGCCAATACCGTTCCAAAAACGCTGGGCAATCCGCTGTATCACTGGACGCACCT
TGAACTACGCCGTCCATTTGGCATTACAGGTACGCTGTTCGGACCGGATACCGCGGAAAGTATCTGGACGCAGTGTAATG
AGAAACTGGCGACGCCGGCCTTTTCCGCGCGCGGTATTATGCAGCAGATGAATGTGCGGATGGTCGGAACCACCGACGAC
CCTATAGATTCTCTGGAATATCACCACCAGATAGCCGCCGACGACAGCATTGATATTGAAGTCGCGCCAAGCTGGCGCCC
CGACAAAGTTTTCAAAATCGAACTGGACGGCTTTGTCGATTACCTGGGGAAACTGGAAGCGGCGGCAGATGTCAGCATTA
CCCGTTTCGACGATTTACGTCAGGCGCTCACTCGCCGCCTCGACCATTTCGCCGCCTGCGGCTGCCGCGCGTCCGATCAT
GGCATTGAAACGCTGCGATTTGCGCCGGTGCCCGACGACGCGCAGCTTGACGCCATTCTGGGCAAACGTCTGGCAGGCGA
AACGTTGAGCGAACTTGAGATCGCCCAGTTTACCACGGCGGTGCTGGTCTGGCTGGGCCGTCAGTACGCCGCGCGCGGCT
GGGTGATGCAGCTACATATTGGCGCGATCCGTAACAATAATACCCGTATGTTCCGCCTGCTCGGGCCGGATACCGGCTTT
GACTCTATTGGCGATAATAACATTAGCTGGGCGCTCTCCCGTTTGCTCGACAGTATGGATGTGACCAATGAACTGCCCAA
GACTATCCTCTATTGCCTGAACCCACGTGATAACGAAGTCCTGGCGACCATGATCGGTAACTTCCAGGGGCCGGGAATTG
CCGGAAAAGTGCAGTTTGGTTCCGGCTGGTGGTTTAACGATCAGAAAGACGGGATGCTGCGCCAACTGGAGCAACTGTCG
CAAATGGGACTGTTAAGTCAGTTTGTCGGGATGCTGACCGACTCCCGCAGTTTCCTTTCTTATACGCGACATGAATATTT
CCGGCGTATTCTCTGTAACCTGCTGGGACAGTGGGCGCAGGACGGAGAGATTCCTGATGATGAAGCGATGTTAAGCCGTA
TGGTTCAGGATATCTGCTTCAATAATGCCCAGCGTTATTTCACGATTAAATAA

Upstream 100 bases:

>100_bases
ACCACGAATTTGTGCAAGCCGTTACCGACGCTTACCAACAGCTATTGCAGAATGGCGCGAAAGCCACGGTAGAAGCGCTG
GCTAAGTAAGGAGATAAATC

Downstream 100 bases:

>100_bases
TCGCTATTAATCTGTGAGCACAGGTTTCAGGTATTTCGAGGGGCAGGAAGGCGGTAAGAGAGTGAGAAATTTAGCAGTAA
CGCACTTTTCCAGCCAAAGT

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKET
SDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDD
PIDSLEYHHQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLGKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDH
GIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGF
DSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLS
QMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK

Sequences:

>Translated_470_residues
MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKET
SDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDD
PIDSLEYHHQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLGKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDH
GIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGF
DSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLS
QMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
>Mature_469_residues
ATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKETS
DYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDP
IDSLEYHHQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLGKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDHG
IETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGFD
SIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQ
MGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=470, Percent_Identity=67.0212765957447, Blast_Score=664, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 53492; Mature: 53361

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHY
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCEEECCCCH
KWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLF
HHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEC
GPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDPIDSLEYHHQIAADDSIDIE
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCEEE
VAPSWRPDKVFKIELDGFVDYLGKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDH
ECCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHI
CCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEV
EEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
LATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQMGLLSQFVGMLTDSRSFLS
HHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure 
ATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHY
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCEEECCCCH
KWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLF
HHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEC
GPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDPIDSLEYHHQIAADDSIDIE
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCEEE
VAPSWRPDKVFKIELDGFVDYLGKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDH
ECCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHI
CCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEV
EEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
LATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQMGLLSQFVGMLTDSRSFLS
HHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA