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The map label for this gene is exuT [H]

Identifier: 29143399

GI number: 29143399

Start: 3135808

End: 3137112

Strand: Reverse

Name: exuT [H]

Synonym: t3055

Alternate gene names: 29143399

Gene position: 3137112-3135808 (Counterclockwise)

Preceding gene: 29143403

Following gene: 29143398

Centisome position: 65.47

GC content: 52.64

Gene sequence:

>1305_bases
ATGAAGATGACAAAATTAAGATGGTGGATTATCGGCCTGGTCTGCGTGGGGACCATCGTAAACTACCTGTCCCGTAGCTC
GCTTAGCGTTGCGGCGCCAGCGATGATGAAAGAACTCCATTTTGATGAGCAACAATATTCCTGGGTGGTGAGCGCCTTCC
AGCTTTGTTACACCATTGCGCAGCCGATCACCGGCTATTTGATGGATGTCATCGGACTGAAAATCGGCTTCTTTATCTTT
GCCTTGTTGTGGTCGCTGATCAACATGGCGCACGCGCTGGCCGGCGGCTGGATAAGCCTGGCATTTCTGCGTGGTCTGAT
GGGGCTAACCGAAGCGTCAGCGATTCCGGCCGGGATTAAAGCCAGCGCCGAATGGTTCCCGACGAAAGAACGTGGTATTG
CGGGGGGCCTGTTTAATATCGGTACTTCAATTGGCGCGATGCTGGCGCCGCCGCTGGTGGTCTGGGCGATGCTGACCTTT
GCTGATAGCGGCATCGGTACTGAAATGGCGTTTGTGATTACCGGTGGGATCGGCGTGCTGTTCGCCATCACCTGGTTCCT
GATTTATAACTCGCCAAATAAACACCCGTGGATCACCCACAAAGAGCTGCGTTATATCGAAGACGGCCAGGAAAGCTATC
TCCAGGACGATAATAAAAAACCGGCCGTTAAAGAGATCGTTAAAAAGCGTAACTTCTGGGCGTTGGCGATTACCCGTTTT
CTTGCTGACCCGGCATGGGGAACGCTGAGTTTCTGGATGCCGCTGTATCTGATTAACGTGATGCATCTGCCGTTAAAAGA
GATCGCCATGTTTGCCTGGCTGCCGTTCCTGGCGGCGGACTTCGGCTGCGTTGCAGGCGGTTTCCTGGCGAAGTTCTTCA
TGGAAAAGATGCACATGACCACGATCAATGCGCGTCGTTGTAGCTTTACCATCGGCGCTGTTTTGATGATTTCGATCGGT
TTTGTCAGCATTACGACTAACCCGTATGTCGCCATTGCATTGATGAGTATTGGCGGTTTTGCGCACCAGACGCTGTCTAC
CGTTGTGATTACCATGAGCGCTGACCTGTTCAAGAAAAATGAGGTCGCGACGGTTGCCGGTCTGGCAGGATCTGCGGCAT
GGATGGGACAGTTAAGCTTCAACCTGTTTATGGGGGCATTGGTCGCTATTATCGGTTACGGCCCGTTCTTCATTGCACTC
AGTCTGTTCGATATTATCGGCGCCATCATCCTGTGGGTACTGATTAAAGATCCGGAAAAGCACCACCCGCCAATGACGGA
ACAGCCGCTGGCGTCTCACCGCTAA

Upstream 100 bases:

>100_bases
GGATGAGAAAATATTGATTGGTCAACCAATTTTTGTAATTTCAGTTTTCCCGCTACAGGTCAGACGGCGCGGAGCTAATG
TTTTTTAACGAGGCTTTATC

Downstream 100 bases:

>100_bases
AGCTGTCTCGGTTTCACAGGCCTGATAAGCGAAGCGCTACCGGGTTCTAACGGCCACCTTCGGGTGGCCGTCTTCATTAC
CCTTATCGGTAAAAATACGC

Product: hexuronate transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKMTKLRWWIIGLVCVGTIVNYLSRSSLSVAAPAMMKELHFDEQQYSWVVSAFQLCYTIAQPITGYLMDVIGLKIGFFIF
ALLWSLINMAHALAGGWISLAFLRGLMGLTEASAIPAGIKASAEWFPTKERGIAGGLFNIGTSIGAMLAPPLVVWAMLTF
ADSGIGTEMAFVITGGIGVLFAITWFLIYNSPNKHPWITHKELRYIEDGQESYLQDDNKKPAVKEIVKKRNFWALAITRF
LADPAWGTLSFWMPLYLINVMHLPLKEIAMFAWLPFLAADFGCVAGGFLAKFFMEKMHMTTINARRCSFTIGAVLMISIG
FVSITTNPYVAIALMSIGGFAHQTLSTVVITMSADLFKKNEVATVAGLAGSAAWMGQLSFNLFMGALVAIIGYGPFFIAL
SLFDIIGAIILWVLIKDPEKHHPPMTEQPLASHR

Sequences:

>Translated_434_residues
MKMTKLRWWIIGLVCVGTIVNYLSRSSLSVAAPAMMKELHFDEQQYSWVVSAFQLCYTIAQPITGYLMDVIGLKIGFFIF
ALLWSLINMAHALAGGWISLAFLRGLMGLTEASAIPAGIKASAEWFPTKERGIAGGLFNIGTSIGAMLAPPLVVWAMLTF
ADSGIGTEMAFVITGGIGVLFAITWFLIYNSPNKHPWITHKELRYIEDGQESYLQDDNKKPAVKEIVKKRNFWALAITRF
LADPAWGTLSFWMPLYLINVMHLPLKEIAMFAWLPFLAADFGCVAGGFLAKFFMEKMHMTTINARRCSFTIGAVLMISIG
FVSITTNPYVAIALMSIGGFAHQTLSTVVITMSADLFKKNEVATVAGLAGSAAWMGQLSFNLFMGALVAIIGYGPFFIAL
SLFDIIGAIILWVLIKDPEKHHPPMTEQPLASHR
>Mature_434_residues
MKMTKLRWWIIGLVCVGTIVNYLSRSSLSVAAPAMMKELHFDEQQYSWVVSAFQLCYTIAQPITGYLMDVIGLKIGFFIF
ALLWSLINMAHALAGGWISLAFLRGLMGLTEASAIPAGIKASAEWFPTKERGIAGGLFNIGTSIGAMLAPPLVVWAMLTF
ADSGIGTEMAFVITGGIGVLFAITWFLIYNSPNKHPWITHKELRYIEDGQESYLQDDNKKPAVKEIVKKRNFWALAITRF
LADPAWGTLSFWMPLYLINVMHLPLKEIAMFAWLPFLAADFGCVAGGFLAKFFMEKMHMTTINARRCSFTIGAVLMISIG
FVSITTNPYVAIALMSIGGFAHQTLSTVVITMSADLFKKNEVATVAGLAGSAAWMGQLSFNLFMGALVAIIGYGPFFIAL
SLFDIIGAIILWVLIKDPEKHHPPMTEQPLASHR

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=355, Percent_Identity=26.7605633802817, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI148743791, Length=254, Percent_Identity=24.8031496062992, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4885441, Length=305, Percent_Identity=25.5737704918033, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI9966811, Length=339, Percent_Identity=25.3687315634218, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI154800443, Length=235, Percent_Identity=26.3829787234043, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI148728191, Length=192, Percent_Identity=23.9583333333333, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI9945322, Length=364, Percent_Identity=23.6263736263736, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI5031955, Length=300, Percent_Identity=22.6666666666667, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367193, Length=435, Percent_Identity=46.4367816091954, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI87082320, Length=431, Percent_Identity=25.5220417633411, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789515, Length=359, Percent_Identity=28.133704735376, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789152, Length=357, Percent_Identity=26.890756302521, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI2367379, Length=295, Percent_Identity=29.1525423728814, Blast_Score=127, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17552542, Length=286, Percent_Identity=28.3216783216783, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71991448, Length=297, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=297, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554148, Length=366, Percent_Identity=22.9508196721311, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24658658, Length=383, Percent_Identity=27.154046997389, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45550460, Length=286, Percent_Identity=27.972027972028, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641682, Length=320, Percent_Identity=25.625, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45550495, Length=428, Percent_Identity=26.4018691588785, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28573708, Length=370, Percent_Identity=25.6756756756757, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573707, Length=370, Percent_Identity=25.6756756756757, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24655255, Length=252, Percent_Identity=26.984126984127, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573299, Length=333, Percent_Identity=24.3243243243243, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583789, Length=278, Percent_Identity=26.6187050359712, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654215, Length=419, Percent_Identity=24.582338902148, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24658689, Length=396, Percent_Identity=23.7373737373737, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24658674, Length=313, Percent_Identity=27.1565495207668, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45552797, Length=396, Percent_Identity=23.7373737373737, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19922400, Length=419, Percent_Identity=24.582338902148, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24639764, Length=352, Percent_Identity=23.5795454545455, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658696, Length=276, Percent_Identity=25.7246376811594, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584153, Length=315, Percent_Identity=22.8571428571429, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550364, Length=348, Percent_Identity=25.2873563218391, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24658666, Length=374, Percent_Identity=24.8663101604278, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24651789, Length=409, Percent_Identity=25.1833740831296, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651787, Length=409, Percent_Identity=25.1833740831296, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24655271, Length=324, Percent_Identity=25.6172839506173, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20130135, Length=324, Percent_Identity=25.6172839506173, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648416, Length=337, Percent_Identity=25.5192878338279, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356189, Length=337, Percent_Identity=25.5192878338279, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281361682, Length=286, Percent_Identity=24.4755244755245, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24580790, Length=296, Percent_Identity=24.6621621621622, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129235, Length=362, Percent_Identity=24.585635359116, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24653727, Length=402, Percent_Identity=23.134328358209, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130167, Length=386, Percent_Identity=22.7979274611399, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47815; Mature: 47815

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMTKLRWWIIGLVCVGTIVNYLSRSSLSVAAPAMMKELHFDEQQYSWVVSAFQLCYTIA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QPITGYLMDVIGLKIGFFIFALLWSLINMAHALAGGWISLAFLRGLMGLTEASAIPAGIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASAEWFPTKERGIAGGLFNIGTSIGAMLAPPLVVWAMLTFADSGIGTEMAFVITGGIGVL
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHH
FAITWFLIYNSPNKHPWITHKELRYIEDGQESYLQDDNKKPAVKEIVKKRNFWALAITRF
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHH
LADPAWGTLSFWMPLYLINVMHLPLKEIAMFAWLPFLAADFGCVAGGFLAKFFMEKMHMT
HCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TINARRCSFTIGAVLMISIGFVSITTNPYVAIALMSIGGFAHQTLSTVVITMSADLFKKN
HCCCHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCHHHHHHHHHHHHEEHHHHHCC
EVATVAGLAGSAAWMGQLSFNLFMGALVAIIGYGPFFIALSLFDIIGAIILWVLIKDPEK
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
HHPPMTEQPLASHR
CCCCCCCCCCCCCC
>Mature Secondary Structure
MKMTKLRWWIIGLVCVGTIVNYLSRSSLSVAAPAMMKELHFDEQQYSWVVSAFQLCYTIA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QPITGYLMDVIGLKIGFFIFALLWSLINMAHALAGGWISLAFLRGLMGLTEASAIPAGIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASAEWFPTKERGIAGGLFNIGTSIGAMLAPPLVVWAMLTFADSGIGTEMAFVITGGIGVL
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHH
FAITWFLIYNSPNKHPWITHKELRYIEDGQESYLQDDNKKPAVKEIVKKRNFWALAITRF
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHH
LADPAWGTLSFWMPLYLINVMHLPLKEIAMFAWLPFLAADFGCVAGGFLAKFFMEKMHMT
HCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TINARRCSFTIGAVLMISIGFVSITTNPYVAIALMSIGGFAHQTLSTVVITMSADLFKKN
HCCCHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCHHHHHHHHHHHHEEHHHHHCC
EVATVAGLAGSAAWMGQLSFNLFMGALVAIIGYGPFFIALSLFDIIGAIILWVLIKDPEK
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
HHPPMTEQPLASHR
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]