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The map label for this gene is ygfA [H]

Identifier: 29143329

GI number: 29143329

Start: 3070370

End: 3070918

Strand: Direct

Name: ygfA [H]

Synonym: t2979

Alternate gene names: 29143329

Gene position: 3070370-3070918 (Clockwise)

Preceding gene: 29143328

Following gene: 29143332

Centisome position: 64.07

GC content: 57.92

Gene sequence:

>549_bases
ATGATTCGGCAACGTCGCCGTGCGCTGACGCCAGAGCAGCAACGCCGCTTTGGTCAACAGGCCGCCGCCCGAATGCTCAG
CTTTCCTCCCGTCGTGATGGCGCACACTGTCGCCGTGTTTCTCTCCTTTGATGGCGAACTCGACACCCAGCCGCTGATAG
AACAGCTATGGCAAGCGGGCAAGCGCGTCTACCTTCCGGTTCTTCATCCCTTCAGCCCTGGCAACCTCCTGTTTCTGCAC
TATCATCCGCAGAGTGCGCTGGTGACCAACCGCTTAAATATCCGGGAGCCACGGCTTGATGTCCGCGACGTATTGCCGCT
GGCAAAGCTGGATGTGCTGGTAACGCCGTTAGTCGCGTTTGACGAAGGCGGGCAGCGTTTAGGCATGGGCGGCGGTTTTT
ATGACCGCACGCTACAAAACTGGCAGCAGCATAAGATCCTACCTGTGGGCTACGCGCATGATTGCCAGTTAGTAGAAAAA
CTGCCGGTTGAAGAGTGGGATATCCCGCTGCCTGCGGTGGTGACGCCGTCCAAAATTTGGGAGTGGTAG

Upstream 100 bases:

>100_bases
GTTACAGCCTGCGGCGGCATCTCGGAGATTCCCCTTCTGACTGGCGACAGCCATGACGCAACTTCCCGAACTCTCTTTAT
CACGACAAGAAATCCGCCGA

Downstream 100 bases:

>100_bases
CCGTGTTTTGTCGATTGACAGCGTCGCTTTTTTGACCTAAATTTCTCGGTGAAGGGTGAGGGAGGCGAACCTCCCTCCTG
CGTACTCACTGTTAATATGC

Product: ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWQAGKRVYLPVLHPFSPGNLLFLH
YHPQSALVTNRLNIREPRLDVRDVLPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEK
LPVEEWDIPLPAVVTPSKIWEW

Sequences:

>Translated_182_residues
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWQAGKRVYLPVLHPFSPGNLLFLH
YHPQSALVTNRLNIREPRLDVRDVLPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEK
LPVEEWDIPLPAVVTPSKIWEW
>Mature_182_residues
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWQAGKRVYLPVLHPFSPGNLLFLH
YHPQSALVTNRLNIREPRLDVRDVLPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEK
LPVEEWDIPLPAVVTPSKIWEW

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=181, Percent_Identity=28.1767955801105, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789278, Length=182, Percent_Identity=86.8131868131868, Blast_Score=332, Evalue=9e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 20877; Mature: 20877

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWQAG
CCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHCC
KRVYLPVLHPFSPGNLLFLHYHPQSALVTNRLNIREPRLDVRDVLPLAKLDVLVTPLVAF
CEEEEEEECCCCCCCEEEEEECCCCHHHCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHC
DEGGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKIW
CCCCCEECCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHCCCCCCCCCCCCEECHHHHC
EW
CC
>Mature Secondary Structure
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWQAG
CCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHCC
KRVYLPVLHPFSPGNLLFLHYHPQSALVTNRLNIREPRLDVRDVLPLAKLDVLVTPLVAF
CEEEEEEECCCCCCCEEEEEECCCCHHHCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHC
DEGGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKIW
CCCCCEECCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHCCCCCCCCCCCCEECHHHHC
EW
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]