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The map label for this gene is recD [H]

Identifier: 29143253

GI number: 29143253

Start: 2985708

End: 2987543

Strand: Reverse

Name: recD [H]

Synonym: t2901

Alternate gene names: 29143253

Gene position: 2987543-2985708 (Counterclockwise)

Preceding gene: 29143254

Following gene: 29143251

Centisome position: 62.34

GC content: 58.55

Gene sequence:

>1836_bases
ATGACAATCCAGAAGCGGTTGCTGGAGGCCGTTGAACAAAAACTCTTACGGCCCATTGATGCCCAGTTTGCTTTAACCGT
CGCCGGTAACGACGATCCCGCCGTGACGCTGGCGGCAGCGCTGCTTAGTCATGACGCAGGTGAAGGTCACGTGTGTCTGC
CGTTGTCGCGTTTAACGTTAACGGAGGAGGCGCATCCCTTACTGGTCGCCTGGATAAGCGAAACGGCTACGCCAATCGAC
TGGAAAAAGCGGTTACTGGCGTCTGCGGCGGTTAGCTGCGGCGATAGCCCCGCGCCGTTAATTCTGTGCGGCGATCGCCT
CTACCTGAATCGCATGTGGTGCAACGAGCGTACGGTTGCGCGCTTTTTTAACGAGGTTAACCAGGCCATCGCCGTAGATG
AAGATCAGTTATCCCGTATTCTGGACGCGCTATTCCCTCCGACAGACGAGGTGAACTGGCAAAAGGTGGCCGCCGCCGTA
GCGCTAACTCGCCGTATCTCCGTGATTTCAGGCGGTCCCGGCACCGGTAAAACCACCACCGTCGCGAAGCTGCTGGCGGC
ATTAATTCAAATGGCGGATGGCGAACGTTGCCGTATCCGGCTGGCGGCGCCAACCGGGAAAGCGGCCGCACGCCTGACGG
AGTCGCTCGGCGCGGCGTTGCGTCAGCTTCCTCTTACCGATGCGCAGAAAAAGCGTATACCGGAGGACGCCAGTACGCTG
CACCGACTGCTGGGCGCACAGCCCGGCAGCCAGCGATTACGCCATCATGCGGGCAACCCGCTGCATCTGGACGTGCTGGT
GGTCGATGAGGCATCAATGATTGATTTGCCGATGATGTCACGTTTGATTGACGCTCTGCCGCCGCACGGGCGGGTCATTT
TTCTTGGCGATCGCGATCAGTTGGCATCCGTTGAGGCGGGCGCTGTGTTGGGCGATATTTGCGCCTATGTCAACGCAGGG
TTTACGGCGGAACGCGCCCGACAGCTAAGTCGACTCACTGGTAGCGCCATTCCGGCGGGGGCCGGAACGCAAGCCGCGTC
TTTACGCGATAGCCTCTGTTTGTTGCAAAAGAGCTACCGTTTCGGCAGCGATTCTGGCATCGGCAAGCTGGCGGCGGCAA
TTAACTGTGGCGACAGGTCGGCAATCCAGGCTGTTTTTCAGCAGGGGTTTAGCGATATAGAGAAGCGTACATTGCAAAGC
AGCGACGATTATGCCGGGATGCTGGATGAAGCGCTGGCGGGCTATGGGCGCTACCTGCGGTTGCTGCATGAAAAAGCGGC
GCCGGAGGCAATCCTTCAGGCTTTCAATGAGTATCAACTGCTTTGTGCGCTGCGCGAAGGCCCATTTGGCGTGAGGGGAC
TGAATGACCGCATTGAGCAGGCGATGGTGCAGCAACGAAAAATTCAGCGGCATCCGCACTCTCGCTGGTATGAAGGGCGT
CCGGTAATGATTGCGCGCAACGATAGCGCGTTGGGGCTATTTAACGGCGATATTGGTATTGCGCTCGATCGCGGGCAGGG
GTTACGCGTCTGGTTTGTGATGCCGGACGGCACGATCAAGTCCGTTCAGCCCAGCCGTCTGCCGGAACATGATACAACCT
GGGCGATGACGGTACATAAATCACAGGGGTCTGAATTTGATCACGCCGCGCTGATTTTACCCAGCCAACGTTCGCCGGTC
GTGACGCGGGAGCTGGTGTATACCGCTGTTACGCGGGCGCGGCGGCGGTTATCGCTGTATGCCGATGAACGGATCCTGGC
AGGCGCGATTGTGACGCGAACGGAACGGCGCAGCGGGTTAGCCACCTTATTTGATGAAGTCAGTCGTATCGGATAA

Upstream 100 bases:

>100_bases
GCGAACGTCCGCAGCAGGGTATTTTTACCACTCGTCCTGCGGCGGCGTTAATTAACCAACTGGATGATATGTTTGCAGGT
GAAATGAGTGAGGAGGCGCA

Downstream 100 bases:

>100_bases
GACGAGTTCTCGCCGGATGGCGACGCGTAGCGTCTTATCCGGCCTCCAAATGATGCTTTCGAGCGTAGGCCTGATAAGCG
CAGCGCCATCAGGCCCCCCT

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MTIQKRLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTLTEEAHPLLVAWISETATPID
WKKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAV
ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAG
FTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQS
SDDYAGMLDEALAGYGRYLRLLHEKAAPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPV
VTRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGLATLFDEVSRIG

Sequences:

>Translated_611_residues
MTIQKRLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTLTEEAHPLLVAWISETATPID
WKKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAV
ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAG
FTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQS
SDDYAGMLDEALAGYGRYLRLLHEKAAPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPV
VTRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGLATLFDEVSRIG
>Mature_610_residues
TIQKRLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTLTEEAHPLLVAWISETATPIDW
KKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAVA
LTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTLH
RLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAGF
TAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQSS
DDYAGMLDEALAGYGRYLRLLHEKAAPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGRP
VMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPVV
TRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGLATLFDEVSRIG

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=604, Percent_Identity=84.7682119205298, Blast_Score=1024, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 66560; Mature: 66429

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQKRLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTL
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEHHHEE
TEEAHPLLVAWISETATPIDWKKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVA
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEHHHHCCHHHHH
RFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAVALTRRISVISGGPGTGKTTT
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHH
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHH
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQ
HHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCHH
LASVEAGAVLGDICAYVNAGFTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQSSDDYAGMLDEALAGYGRYLR
CCCCCCHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LLHEKAAPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
HHHHHCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHK
EEEEEECCCEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEC
SQGSEFDHAALILPSQRSPVVTRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHH
ATLFDEVSRIG
HHHHHHHHHCC
>Mature Secondary Structure 
TIQKRLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTL
CHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEHHHEE
TEEAHPLLVAWISETATPIDWKKRLLASAAVSCGDSPAPLILCGDRLYLNRMWCNERTVA
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEHHHHCCHHHHH
RFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAVALTRRISVISGGPGTGKTTT
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHH
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHH
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPPHGRVIFLGDRDQ
HHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCHH
LASVEAGAVLGDICAYVNAGFTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQSSDDYAGMLDEALAGYGRYLR
CCCCCCHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LLHEKAAPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
HHHHHCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHK
EEEEEECCCEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEC
SQGSEFDHAALILPSQRSPVVTRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHH
ATLFDEVSRIG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]