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The map label for this gene is argA [H]

Identifier: 29143252

GI number: 29143252

Start: 2984274

End: 2985605

Strand: Direct

Name: argA [H]

Synonym: t2900

Alternate gene names: 29143252

Gene position: 2984274-2985605 (Clockwise)

Preceding gene: 29143248

Following gene: 29143266

Centisome position: 62.28

GC content: 52.4

Gene sequence:

>1332_bases
ATGATAAAGGAACGTAAAACCGAACTGGTAGAAGGGTTTCGCCATTCAGTTCCCTATATCAATACCCATCGCGGAAAAAC
CTTTGTCATTATGCTCGGCGGCGAAGCCATTGAGCATGACAATTTTTCCAGCATCGTTAGCGATATCGGGCTACTGCATA
GCCTCGGTATTCGCCTTGTCGTGGTGTATGGCGCGCGACCGCAAATCGACGCCAATCTGGCCGCGCATCATCATGAACCG
ATTTACCACAAAAACACACGGGTGACGGACGCCAAAACACTGGAGCTGGTGAAACAGGCCGCCGGTTTACTCCAGCTTGA
TATTACCGCCCGTCTGTCGATGAGTCTGAACAATACGCCGTTGCAGGGCGCGCACATTAATGTCGTCAGCGGCAATTTCA
CCATTGCGCAGCCGCTGGGCGTTGATGATGGCGTGGACTACTGTCATAGCGGCCGTATCCGGCGCATTGATGAAGATGCG
ATCAACCGCCAGTTGGATAACGGCGCGATCGTTCTGATGGGGCCGGTCGCCGTCTCAGTGACCGGCGAAAGTTTTAATCT
GACCTCAGAAGAGATTGCCACTCAACTCGCCGTTAAACTGAAAGCGGAAAAAATGATCGGTTTCTGTTCTTCTCAGGGCG
TTACCAATAGCGAGGGCGGCATCATTTCTGAACTCTTCCCGAATGAAGCGCAGGCGCGGGTGGAAGAGTTGGAAGCGCAG
GGCGATTACAACTCCGGAACCGTACGTTTTTTGCGCGGCGCGGTAAAAGCCTGTCGTAGCGGCGTTCGTCGTTGCCATCT
GATCAGCTATCAGGAAGATGGCTCGCTATTACAGGAATTGTTCTCGCGTGATGGTATCGGTACGCAGATCGTCATGGAGA
GCGCCGAGCAGATCCGCCGCGCTACCATCAACGATATTGGCGGTATTCTGGAGCTTATCCGCCCACTGGAACAGCAGGGC
ATTCTGGTACGCCGTTCCCGTGAACAACTGGAGATGGAGATCGATAAATTTACCATTATTCAGCGCGATAATATGACTAT
CGCTTGCGCGGCGCTGTATCCTTTTGTGGAAGAGAAAATAGGCGAAATGGCCTGCGTAGCGGTACATCCGGATTATCGCA
GCTCATCGCGTGGAGAAGTGCTTCTGGAGCGGGTTGCCGCCCAGGCACGGCAAATGGGGCTGCGTAAATTGTTTGTGTTG
ACGACGCGCAGTATTCACTGGTTCCAGGAGCGCGGTTTTACGCCTGTCGATATTGAGTTACTGCCTGAGAGCAAGAAAAA
AATGTATAACTATCAGCGACGTTCAAAGGTGCTGATGGCAGATTTAGGATAA

Upstream 100 bases:

>100_bases
GAAAAGCGATCGGACCGCATAAAATTTACGCTTGCACAGAGGGCAAAAACAGAATAAAAATACACTAATTTCGAATAATA
ATTCACTAGTGGGGCGCGCA

Downstream 100 bases:

>100_bases
CAAGGGGGGCCTGATGGCGCTGCGCTTATCAGGCCTACGCTCGAAAGCATCATTTGGAGGCCGGATAAGACGCTACGCGT
CGCCATCCGGCGAGAACTCG

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MIKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHDNFSSIVSDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEP
IYHKNTRVTDAKTLELVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFTIAQPLGVDDGVDYCHSGRIRRIDEDA
INRQLDNGAIVLMGPVAVSVTGESFNLTSEEIATQLAVKLKAEKMIGFCSSQGVTNSEGGIISELFPNEAQARVEELEAQ
GDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGSLLQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQG
ILVRRSREQLEMEIDKFTIIQRDNMTIACAALYPFVEEKIGEMACVAVHPDYRSSSRGEVLLERVAAQARQMGLRKLFVL
TTRSIHWFQERGFTPVDIELLPESKKKMYNYQRRSKVLMADLG

Sequences:

>Translated_443_residues
MIKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHDNFSSIVSDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEP
IYHKNTRVTDAKTLELVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFTIAQPLGVDDGVDYCHSGRIRRIDEDA
INRQLDNGAIVLMGPVAVSVTGESFNLTSEEIATQLAVKLKAEKMIGFCSSQGVTNSEGGIISELFPNEAQARVEELEAQ
GDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGSLLQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQG
ILVRRSREQLEMEIDKFTIIQRDNMTIACAALYPFVEEKIGEMACVAVHPDYRSSSRGEVLLERVAAQARQMGLRKLFVL
TTRSIHWFQERGFTPVDIELLPESKKKMYNYQRRSKVLMADLG
>Mature_443_residues
MIKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHDNFSSIVSDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEP
IYHKNTRVTDAKTLELVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFTIAQPLGVDDGVDYCHSGRIRRIDEDA
INRQLDNGAIVLMGPVAVSVTGESFNLTSEEIATQLAVKLKAEKMIGFCSSQGVTNSEGGIISELFPNEAQARVEELEAQ
GDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGSLLQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQG
ILVRRSREQLEMEIDKFTIIQRDNMTIACAALYPFVEEKIGEMACVAVHPDYRSSSRGEVLLERVAAQARQMGLRKLFVL
TTRSIHWFQERGFTPVDIELLPESKKKMYNYQRRSKVLMADLG

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=443, Percent_Identity=93.4537246049661, Blast_Score=862, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320913, Length=345, Percent_Identity=24.6376811594203, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49309; Mature: 49309

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHDNFSSIVSDIGLLHSLGIRLV
CCCCHHHHHHHHHHHCCCEEEECCCCEEEEEECCCEECCCCHHHHHHHHHHHHHCCEEEE
VVYGARPQIDANLAAHHHEPIYHKNTRVTDAKTLELVKQAAGLLQLDITARLSMSLNNTP
EEECCCCCCCCCHHHCCCCCCEECCCCCCHHHHHHHHHHHCCEEEEEEEEEEEEECCCCC
LQGAHINVVSGNFTIAQPLGVDDGVDYCHSGRIRRIDEDAINRQLDNGAIVLMGPVAVSV
CCCCEEEEEECCEEEECCCCCCCCCHHHCCCCCEECCHHHHHCCCCCCEEEEEECEEEEE
TGESFNLTSEEIATQLAVKLKAEKMIGFCSSQGVTNSEGGIISELFPNEAQARVEELEAQ
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHC
GDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGSLLQELFSRDGIGTQIVMESAEQIRR
CCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
ATINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIQRDNMTIACAALYPFVEEKI
HHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHCEEEEEEECCCEEEHHHHHHHHHHHH
GEMACVAVHPDYRSSSRGEVLLERVAAQARQMGLRKLFVLTTRSIHWFQERGFTPVDIEL
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHCCCCEEEEEE
LPESKKKMYNYQRRSKVLMADLG
CCCHHHHHHHHHHHCEEEEECCC
>Mature Secondary Structure
MIKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHDNFSSIVSDIGLLHSLGIRLV
CCCCHHHHHHHHHHHCCCEEEECCCCEEEEEECCCEECCCCHHHHHHHHHHHHHCCEEEE
VVYGARPQIDANLAAHHHEPIYHKNTRVTDAKTLELVKQAAGLLQLDITARLSMSLNNTP
EEECCCCCCCCCHHHCCCCCCEECCCCCCHHHHHHHHHHHCCEEEEEEEEEEEEECCCCC
LQGAHINVVSGNFTIAQPLGVDDGVDYCHSGRIRRIDEDAINRQLDNGAIVLMGPVAVSV
CCCCEEEEEECCEEEECCCCCCCCCHHHCCCCCEECCHHHHHCCCCCCEEEEEECEEEEE
TGESFNLTSEEIATQLAVKLKAEKMIGFCSSQGVTNSEGGIISELFPNEAQARVEELEAQ
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHC
GDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGSLLQELFSRDGIGTQIVMESAEQIRR
CCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
ATINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIQRDNMTIACAALYPFVEEKI
HHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHCEEEEEEECCCEEEHHHHHHHHHHHH
GEMACVAVHPDYRSSSRGEVLLERVAAQARQMGLRKLFVLTTRSIHWFQERGFTPVDIEL
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHCCCCEEEEEE
LPESKKKMYNYQRRSKVLMADLG
CCCHHHHHHHHHHHCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]