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The map label for this gene is sipD

Identifier: 29143144

GI number: 29143144

Start: 2864622

End: 2865644

Strand: Reverse

Name: sipD

Synonym: t2785

Alternate gene names: 29143144

Gene position: 2865644-2864622 (Counterclockwise)

Preceding gene: 29143145

Following gene: 29143143

Centisome position: 59.8

GC content: 46.92

Gene sequence:

>1023_bases
ATGCTTAATATTCAAAATTATTCCGCTTCTCCTCATCCGGGGATCGTTGCCGAACGGCCGCAGACTCCTTCGGCGAGCGA
GCACGCCGAGATTGCCGTGGTACCGTCTACCACAGAACATCGCGGCACAGATATCATTTCATTATCGCAGGCGGCTACTA
AAATCCAGCAGGCACAGCAGACGCTGCAGTCAACGCCACCGATTTCTGAAGAGAATAATGACGAGCGCACGCTGGCGCGC
CAACAGTTGACCAGCAGCCTGAATGCGCTGGCGAAGTCCGGCGTGTCATTATCCGCAGAACAAAATGAGAACCTGCGGAG
CACGTTTTCTGCGCCGACGTCGGCCTTATTTAGCGCTTCGCCTATGGCGCAGCCGAGAACAACCATTTCTGATGCTGAGA
TTTGGGATATGGTTTCCCAAAATATATCGGCGATAGGTGACAGCTACCTGGGCGTTTATGAAAACGTTGTCGCAGTCTAT
ACCGATTTTTATCAGGCCTTCAGTGATATTCTTTCCAAAATGGGAGGCTGGTTATCGCCTGGTAAGGATGGAAATACCAT
TAAGCTAAATGTTGACTCACTTAAAAGTGAAATAAGTAGTTTAATTAATAAATACACTCAAATAAATAAAAATACGATTT
TATTTCCCTCGCAAACTGGCAGCGGAATGACAACAGCAACGAAAGCGGAAGCTGAGCAGTGGATTAAAGAATTGAATTTA
CCGGACAGCTGTCTAAAGGCGTCTGGTTCTGGTTATGTCGTACTGGTGGATACGGGGCCACTGAGCAAAATGGTTAGCGA
TCTTAATGGAATAGGATCGGGTTCAGCCCTTGAACTGGATAACGCCAAATATCAAGCCTGGCAGTCGGGTTTTAAAGCAC
AGGAAGAAAATCTGAAAACCACATTACAGACGCTGACGCAAAAATATAGCAATGCCAATTCATTGTACGACAACCTGGTA
AAAGTGCTGAGCAGTACGATAAGTAGCAGCCTGGAAACCGCCAAAAGCTTCCTGCAAGGATAA

Upstream 100 bases:

>100_bases
CGCTGCTATCGCAGGCAATATTCGCGCTTAATCTGACAGATCAACTATACGCCATCAGGGGGGGATTTAATCGCCCTCCT
GATGGCGAACTGGGGATATT

Downstream 100 bases:

>100_bases
CAGAAGAGGATATTAATAATGGTTACAAGTGTAAGAACTCAGCCCCCCGTCATAATGCCAGGTATGCAGACCGAGATCAA
AACGCAGGCCACGAATCTTG

Product: pathogenicity island 1 effector protein

Products: NA

Alternate protein names: Salmonella invasion protein D

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTDIISLSQAATKIQQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSTFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGMTTATKAEAEQWIKELNL
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLV
KVLSSTISSSLETAKSFLQG

Sequences:

>Translated_340_residues
MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTDIISLSQAATKIQQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSTFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGMTTATKAEAEQWIKELNL
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLV
KVLSSTISSSLETAKSFLQG
>Mature_340_residues
MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTDIISLSQAATKIQQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSTFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGMTTATKAEAEQWIKELNL
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLV
KVLSSTISSSLETAKSFLQG

Specific function: Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of sipA, sipB, and sipC

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS). Localizes to the tip of the external secretion needle that is part of the TTSS apparatus (By similarity)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the invasin protein D family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SIPD_SALPA (Q5PEC2)

Other databases:

- EMBL:   CP000026
- RefSeq:   YP_151910.1
- ProteinModelPortal:   Q5PEC2
- SMR:   Q5PEC2
- GeneID:   3176862
- GenomeReviews:   CP000026_GR
- KEGG:   spt:SPA2741
- HOGENOM:   HBG671452
- OMA:   NYLGVYE
- ProtClustDB:   PRK15330
- BioCyc:   SENT295319:SPA2741-MONOMER
- GO:   GO:0009405
- InterPro:   IPR009483
- InterPro:   IPR013386
- TIGRFAMs:   TIGR02553

Pfam domain/function: PF06511 IpaD

EC number: NA

Molecular weight: Translated: 36549; Mature: 36549

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTDIISLSQAATKIQQAQQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
TLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQNENLRSTFSAPTSALFSAS
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHCCC
PMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVYTDFYQAFSDILSKMGGWLSP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGMTTATKAEAEQWIKELNL
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCC
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKT
CHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
TLQTLTQKYSNANSLYDNLVKVLSSTISSSLETAKSFLQG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTDIISLSQAATKIQQAQQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
TLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQNENLRSTFSAPTSALFSAS
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHCCC
PMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVYTDFYQAFSDILSKMGGWLSP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGMTTATKAEAEQWIKELNL
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCC
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKT
CHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
TLQTLTQKYSNANSLYDNLVKVLSSTISSSLETAKSFLQG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA