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The map label for this gene is hypA

Identifier: 29143115

GI number: 29143115

Start: 2838545

End: 2838901

Strand: Direct

Name: hypA

Synonym: t2756

Alternate gene names: 29143115

Gene position: 2838545-2838901 (Clockwise)

Preceding gene: 29143102

Following gene: 29143116

Centisome position: 59.24

GC content: 48.18

Gene sequence:

>357_bases
ATGCACGAAATCACCCTCTGCCAACGGGCACTGGAATTGATTGAACAACAGGCTTCAGCATACGGTGCAAAACGTGTGAC
AGCCGTCTGGATCAAAATTGGCGCATTTTCTTGCGTGGAAACCAGCGCTCTTTCCTTTTGTTTTGATCTGGTATGCCGCG
GCACGATAGCAGAAGGTTGTAAACTGCACCTCGAAGAACAGGAAGCCGAATGCTGGTGTGAGCATTGTCAACAATATGTC
ACGTTGTTAACCCACCGTGTACGTCGTTGTCCGCAATGTCATAGCGATACGCTGCGAATTGTGGCCGATGACGGCTTACA
AATTCGGCGCATAGAGATTGATGAAACTGAAGATTAA

Upstream 100 bases:

>100_bases
TGACGACATGTCATTTCGTCATCGTCGACATTAACCTGCCAGGGGATACAAATATTGGCATAAATATTGCTTTACAGGGG
CAACCACTACGGGAGGCGAT

Downstream 100 bases:

>100_bases
TGCCGGATAAGACGCTCGCGTCGCCATCCGGCAGAAAGCCTGTAACAAGAAGAAGATCAGGAGTAAGCGATGTGTACGAC
TTGCGGTTGCGCTGAAGGCA

Product: hydrogenase nickel incorporation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MHEITLCQRALELIEQQASAYGAKRVTAVWIKIGAFSCVETSALSFCFDLVCRGTIAEGCKLHLEEQEAECWCEHCQQYV
TLLTHRVRRCPQCHSDTLRIVADDGLQIRRIEIDETED

Sequences:

>Translated_118_residues
MHEITLCQRALELIEQQASAYGAKRVTAVWIKIGAFSCVETSALSFCFDLVCRGTIAEGCKLHLEEQEAECWCEHCQQYV
TLLTHRVRRCPQCHSDTLRIVADDGLQIRRIEIDETED
>Mature_118_residues
MHEITLCQRALELIEQQASAYGAKRVTAVWIKIGAFSCVETSALSFCFDLVCRGTIAEGCKLHLEEQEAECWCEHCQQYV
TLLTHRVRRCPQCHSDTLRIVADDGLQIRRIEIDETED

Specific function: Not required for the formation of hydrogenases 1 and 2. Plays probably a regulatory role

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789081, Length=115, Percent_Identity=86.9565217391304, Blast_Score=210, Evalue=2e-56,
Organism=Escherichia coli, GI1789365, Length=114, Percent_Identity=48.2456140350877, Blast_Score=118, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_SALTI (P64420)

Other databases:

- EMBL:   AL627276
- EMBL:   AE014613
- RefSeq:   NP_457248.1
- RefSeq:   NP_806457.1
- GeneID:   1068943
- GeneID:   1249283
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2756
- KEGG:   sty:STY2976
- HOGENOM:   HBG688671
- OMA:   CFELVCR
- ProtClustDB:   PRK03681
- BioCyc:   SENT209261:T2756-MONOMER
- BioCyc:   SENT220341:STY2976-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 13486; Mature: 13486

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
8.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEITLCQRALELIEQQASAYGAKRVTAVWIKIGAFSCVETSALSFCFDLVCRGTIAEGC
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
KLHLEEQEAECWCEHCQQYVTLLTHRVRRCPQCHSDTLRIVADDGLQIRRIEIDETED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCCC
>Mature Secondary Structure
MHEITLCQRALELIEQQASAYGAKRVTAVWIKIGAFSCVETSALSFCFDLVCRGTIAEGC
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
KLHLEEQEAECWCEHCQQYVTLLTHRVRRCPQCHSDTLRIVADDGLQIRRIEIDETED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504