Click here to switch to the map view.

The map label for this gene is norW [H]

Identifier: 29143102

GI number: 29143102

Start: 2825254

End: 2826387

Strand: Direct

Name: norW [H]

Synonym: t2743

Alternate gene names: 29143102

Gene position: 2825254-2826387 (Clockwise)

Preceding gene: 29143101

Following gene: 29143115

Centisome position: 58.96

GC content: 56.53

Gene sequence:

>1134_bases
ATGAGTCGGGGGATCATCATTATTGGGTCGGGCTTCGCCGCCCGCCAGCTCGTCAAAAATATCCGTAAACAAGATGCGCA
TGTGCCGTTAACTCTGATTGCGGCGGACAGCATGGATGAGTACAACAAGCCCGATCTCAGCCACGTTATCAGCCAGTCGC
AGCGCGCCGATGATCTCACCCGCCAGTTAGCGGGGGAATTTGCTGAACAGTTTAATCTACGACTGTTCCCGCATACCTGG
GTTACTGACATTGATGCCGATGCCCATGTGGTGAAAAGTCAGGATAAGCAGTGGCAGTACGACAAGCTGGTACTGACGAC
CGGGGCGACAGCCTTTGTGCCGCCGATTGCAGGACGTGAGTTAATGCTTACTTTGAATAGCCAGCAGGAGTACCGCGCCT
GTGAGACACCACTGCGCGACGCGCAGCGAGTGCTGATTGTCGGCGGCGGTCTCATTGGCAGTGAATTAGCAATGGATTTC
TGCCGCGCCGGGAAAACGGTAACGCTGATGGATAACGCCGCCAGCCTTCTCGCCTCACTGATGCCACCGGAAGTGAGCAG
TCGCTTACAGCATCACCTGACCGATATGGGGGTGCATCTGCTGCTGAAATCGCAGTTGCAAAAACTGGAGAAAACCGAAG
CCGGTATCCGCGCTACGCTGGTAAGCCAGCATAGTATTGAGGTCGATGCGGTGATTGCCGCCACCGGCTTACGCCCGGAG
ACCGCTCTGGCGCGCCGCGCCGGGGTAGCCGTCAACCGCGGCGTCTGCGTGGATAGCTATCTACAGACCAGTCACCCGGA
TATTTATGCGATCGGCGATTGCGCGGAAATCAATGGTCAGGTGCTGCCCTTCCTGCAACCGATCCAGTTAAGCGCGATGT
ACCTGGCGAAAAATCTGCTCGGCGGCAACGCGCCGCTGAAGCTACCGGCGATGCTGGTCAAAGTCAAAACGCCGGAACTG
CCGCTGCATCTGGCGGGAGAAACTCAGCGCCGCGATTTAAGCTGGCAGATTACCGCAGAATCTGACGGTATGATTGCCAA
AGGCATGAGTGGAGAAGGCCAGCTACGCGCCTTTGTGGTGAGTGAAGACCGCATGAAAGAGGCCTTTGCACTGCTGAAAA
CGTTGTCGGTATAA

Upstream 100 bases:

>100_bases
TCGCGCCGGGTACGCCGTGGAGCGACGTGCCGGATAACTTCCTGTGCCCGGAATGTTCATTAGGTAAAGACGTGTTCGAC
GTACTGGCGACGGAGGCAAA

Downstream 100 bases:

>100_bases
GCCTGTGATGCCGGATAGCGCCGCTTCGCGTCTTATCCGGCCTACGAGTGAGCATCTGTTTACACGCCGGATAAGGCGCA
GCCGCCATCCGGCGCCCTAC

Product: nitric oxide reductase

Products: NAD; reduced flavorubredoxin; H2O [C]

Alternate protein names: Flavorubredoxin reductase; FlRd-reductase; FlavoRb reductase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTW
VTDIDADAHVVKSQDKQWQYDKLVLTTGATAFVPPIAGRELMLTLNSQQEYRACETPLRDAQRVLIVGGGLIGSELAMDF
CRAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQHSIEVDAVIAATGLRPE
TALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPEL
PLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV

Sequences:

>Translated_377_residues
MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTW
VTDIDADAHVVKSQDKQWQYDKLVLTTGATAFVPPIAGRELMLTLNSQQEYRACETPLRDAQRVLIVGGGLIGSELAMDF
CRAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQHSIEVDAVIAATGLRPE
TALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPEL
PLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV
>Mature_376_residues
SRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTWV
TDIDADAHVVKSQDKQWQYDKLVLTTGATAFVPPIAGRELMLTLNSQQEYRACETPLRDAQRVLIVGGGLIGSELAMDFC
RAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQHSIEVDAVIAATGLRPET
ALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPELP
LHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV

Specific function: One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=321, Percent_Identity=21.4953271028037, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI226437568, Length=281, Percent_Identity=21.7081850533808, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI65787454, Length=321, Percent_Identity=21.4953271028037, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1789065, Length=375, Percent_Identity=85.3333333333333, Blast_Score=664, Evalue=0.0,
Organism=Escherichia coli, GI1789765, Length=321, Percent_Identity=26.4797507788162, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788892, Length=274, Percent_Identity=27.7372262773723, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787352, Length=251, Percent_Identity=27.8884462151394, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=317, Percent_Identity=22.0820189274448, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639257, Length=284, Percent_Identity=25, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281359715, Length=284, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281359713, Length=284, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639250, Length=284, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI18543267, Length=284, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639252, Length=284, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 41150; Mature: 41019

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLT
CCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
RQLAGEFAEQFNLRLFPHTWVTDIDADAHVVKSQDKQWQYDKLVLTTGATAFVPPIAGRE
HHHHHHHHHHCCCEECCCCCEECCCCCHHHHCCCCCCCCCCEEEEEECCCEECCCCCCCE
LMLTLNSQQEYRACETPLRDAQRVLIVGGGLIGSELAMDFCRAGKTVTLMDNAASLLASL
EEEEECCCHHHHHHCCCHHCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECHHHHHHHHH
MPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQHSIEVDAVIAATGLRPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCH
TALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLL
HHHHHHCCCEECCCCCHHHHHHCCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHH
GGNAPLKLPAMLVKVKTPELPLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVV
CCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEEEE
SEDRMKEAFALLKTLSV
CHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLT
CCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
RQLAGEFAEQFNLRLFPHTWVTDIDADAHVVKSQDKQWQYDKLVLTTGATAFVPPIAGRE
HHHHHHHHHHCCCEECCCCCEECCCCCHHHHCCCCCCCCCCEEEEEECCCEECCCCCCCE
LMLTLNSQQEYRACETPLRDAQRVLIVGGGLIGSELAMDFCRAGKTVTLMDNAASLLASL
EEEEECCCHHHHHHCCCHHCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECHHHHHHHHH
MPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQHSIEVDAVIAATGLRPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCH
TALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLL
HHHHHHCCCEECCCCCHHHHHHCCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHH
GGNAPLKLPAMLVKVKTPELPLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVV
CCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEEEE
SEDRMKEAFALLKTLSV
CHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; oxidized flavorubredoxin; O2 [C]

Specific reaction: NADH + oxidized flavorubredoxin + O2 = NAD + reduced flavorubredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA